Team:NYMU-Taipei/project/2c

From 2014.igem.org

(Difference between revisions)
Line 11: Line 11:
<h2> Purpose </h2>
<h2> Purpose </h2>
 +
<p> Due to the idea of phage threshold control of the number of ''Streptococcus mutans'' in prevention of the second-dominant strain in the oral cavity, we envision a possibility to trigger another killing system to reach synergistic effect on diminishing ''S.mutans.''
 +
If the threshold terminators were passed, the downstream signaling pathway would be switched on and contact with the engineered ''E.coli.''

Revision as of 02:26, 16 August 2014

X
Next ⇒
⇐ Prev
...

communication

The third "C" product, "Communication."

The two main organisms we adapted in our project are Escherichia coli and M102bacteriophage, respectively. Our team comes up with an interesting thought that we want to let these two entirely different organisms collaborate,thus we decided to use one of the most commonly seen quorum sensing chemicals, AHL, N-Acyl homoserine lactone, as our indicator between phage and E.coli.

Purpose

Due to the idea of phage threshold control of the number of Streptococcus mutans in prevention of the second-dominant strain in the oral cavity, we envision a possibility to trigger another killing system to reach synergistic effect on diminishing S.mutans. If the threshold terminators were passed, the downstream signaling pathway would be switched on and contact with the engineered E.coli.