Team:SDU-Denmark/Tour27

From 2014.igem.org

1.1.1.3 - homoserine dehydrogenase

L-aspartate-4-semialdehyde + NAD(P)H+H+ homoserine + NAD(P)+


Model submitted by SDU-Denmark 2014

Notes/Assumption:
We do not include NAD(P)H+H+ and NAD(P)+ in the model.

The reaction is on the form: A B
A: L-aspartate-4-semialdehyde
B: Homoserine

Rate function:

   (click picture for copyable formula with constants inserted)


Constant Value Comment Reference
Vmax,forward 2.8 Value obtained from Glycine Max Brenda
Vmax,reverse 0.24 Value obtained from Glycine Max Brenda
Km,A 0.17 Value obtained from E. coli Brenda
Km,B 0.013 Value obtained from E. coli Brenda


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