Team:SDU-Denmark/Tour53
From 2014.igem.org
Business plan - Nutrition Generator
Give a man some food, and you feed him for a day, give a man a Nutrition Generator and you feed him for a lifetime.
Edible coli is a fantastic bacteria that can be used for many purposes and benefit many people. However, it
can be difficult to understand the basic idea behind the innovative bacteria without explaining it with a final
product. Therefore, we have written a business plan, describing one of the many possible end products
Edible coli can be used for. This business plan explains the implementations of our idea by delineating the
amazing food tank: Nutrition Generator.
Please note that the GMO (Gene Modified Organism) legislation does not allow the production and
marketing of a Nutrition Generator, as it is not allowed to sell edible gene modified
bacteria.
Source:
Regulation (EC) No 1829/2003 of the European Parliament and of the Council of 22 September 2003 concerning the
traceability and labelling of genetically modified organisms and the traceability of food and feed products
produced from genetically modified organisms and amending Directive 2001/18/EC (Official Journal L 268,
18/10/2003 P. 0024 – 0028)
(Link)
The ethical issues about the GMO legislation are discussed here.
This business plan describes a fictional product idea and not a fully developed and legally tested product.
Nutrition Generator
Nutrition Generator is an innovative and revolutionary tank that converts biological material that is not
degradable by humans, to protein and fat rich food.
Every day people die as a consequence of undernourishment, mostly seen in Africa, South-East Asia
and Latin America.
bacteria.
Source:
Save the Children, 2014: Where do we work.
(Link)
In the early childhood chronic undernourishment can lead to underdevelopment of the brain, a weak immune system, and
death.
Source:
NHC, 2011: Symptoms of malnutrition.
(Link)
Malnourished people need proteins and fatty acids, which the available resources in low-income countries,
as for example Ghana, Congo and India, cannot cover for every single
inhabitant.
Source:
Central intelligence Agency, 2014: The World Factbook.
(Link)
Nutrition Generator can solve problems with undernourishment and in addition be used all over the world
as a supplement for malnourished, vegans and vegetarians by supplying the right amounts of essential and
nonessential amino acids, as well as essential ω3 and ω6 fatty acids.
The tank - The product idea
Nutrition Generator is build up by two tanks, one bacteria tank and one cellulose tank. The two tanks are
directly connected with a bacterial flow tube, and indirectly with a bacteria reflow tube, that also includes a
pump. The tubes are equipped with a safety closure system, so that bacteria only can be transferred when
needed, and contamination risk is minimized.
The bacteria tank contains Edible coli, a gene modified bacteria that expresses huge amounts of proteins
and fatty acids by using cellulose as carbon source. It is not possible to open the bacteria tank, which avoids
contamination by other bacteria or fungi. The tank is designed to contain Edible coli from the beginning,
which will reproduce, so that it is not required to change or add new bacteria at any time. Furthermore the
tank will contain and pH indicator and a thermometer, so that it is easy to keep an eye on and maintain the
optimal growth conditions of the bacteria.
The cellulose tank is much larger than the bacteria tank. It has a lid in the top, where cellulose containing
materials, as for example plant material, can be added, and through which the tank can be cleaned. In the
bottom of the tank there is a tap where the final product can be taken.
The cellulose tank functions as an autoclave when closed and heated. For this aim the tank has a valve, with
which the pressure can be regulated.
To start the expression of proteins and fatty acids by Edible coli, a small amount of the bacteria is
transferred from the bacteria tank to the cellulose tank. Then cellulose is added into the cellulose tank
through the lid. The bacteria will now begin to degrade cellulose and express ω3 and ω6 fatty-acid and
OneProt, a protein that contains all the essential amino acids in the right ratio, as well as all the
nonessential amino acids. After a while the bacteria is autoclaved, so that the end product does not contain
any living bacteria.
Before the final product can be tapped, a small amount must be pumped through the bacteria reflow tube
into the bacteria tank. The final product functions as media for the living bacteria in the bacteria tank.
Now the final product can be tapped and enjoyed.
Nutrition Generator is available as both electric and non-electric version, for which the non electric version
requires heat energy from e.g. a campfire. Specialized staff is only needed once, when the product is set up.
Afterwards the use of the product is very simple and even children can operate the tank. Wear and tear
that might appear after long term use can be fixed with simple handyman skills.
Edible coli - The core product
Edible coli is a non pathogenic Escherichia coli bacteria that is genetically modified. The bacteria is designed with a plasmid, containing the genes for OneProt and ω3 and ω6 fatty acid biosynthesis. The promoters are activated in the presence of cellulose. OneProt is a protein that includes all the essential and non essential amino acids in the right ratio recommended by WHO (World Health Organization). For those wanting Edible coli with taste, the bacteria is also available with a high expressed lemon flavor gene.
Safety
Nutrition Generator is a safe and closed system and without any risk of bacterial infection. When Edible coli is transferred from the bacteria tank into the cellulose tank, the lid and tap are closed. Furthermore, before the end product is tapped from the tank, the entire contents of the cellulose tank is autoclaved, a process that kill bacteria and other micro-organisms. In that way, no living bacteria will ever escape out of the tank.
Customer - who is supposed to buy the product
Charitable organizations are the main customers of Nutrition Generator. They buy it for poor
undernourished people, who aren’t able to pay it themselves, as the organizations beforehand have
contact and connection to areas of need.
To get the product sold to charitable organizations, it is important to draw attention to the many benefits
of the product and especially to the fact, that Nutrition Generator can save many lives with a single
investigation.
Nutrition Generator is, however, not only useful for undernourished poor people; all people in the world
can benefit from the protein and fat rich product of the tank, and therefore also private consumer, public
institutions and many more can be customers.
Key partners - with whom do we work with
Our main key partners will be charity organizations, as these have a close connection to trouble spots in developing countries, as well as a good contact to supplier and social helpers. In addition, we will work together with engineers, who can help us design and develop the product. At least, specialized councils can help us solving ethical issues that might emerge.
Consumer - who is supposed to use the product
All people in the entire world are possible consumers of Nutrition Generator, but as long as people have access to other food sources, we don’t expect that they will consume GMO produced food. The target group is undernourished people in developing countries, who don’t have the money and access to protein and fat rich food. But also vegans and vegetarians can benefit from this product, as it is a very good alternative protein and fat source, for those who do not eat animal products.
Demography - where shall our product be used
The target place is where people suffer from undernourishment. As mentioned above Africa, South-East Asia and Latin America are examples of those areas, where many inhabitants are poor and undernourished. Nutrition Generator may advantageously also be used in crisis areas, as for example war zones or areas affected by natural disasters. Furthermore, the product is also a great food source for private homes in high-income countries, where people can use the food product as a supplement to the diet.
Transport - how will our product get to the consumer
To meet the main objective of Nutrition Generator, to provide a food source for poor and undernourished people in low-income countries, we need the help of charitable organizations that deliver and set up our product. Charities often send food and other items to developing countries, and as they know how to do so, they are our perfect partners in that term. Along with the product, there must also be a facilitator present, who can set up the product, and instruct consumers to the use and application of the product.
Funding - who will pay production and costs
The production of the first Nutrition Generators needs funding by donation, as the target consumers are not able to pay for the product. We expect that the product will be a great success, so that, after a while, also well-nourished people, who have access to many different food sources, will buy the product and thus contribute to the production costs.
Competitors - similar product availeble on the market
Nutrition Generator is the first product of its kind and there are no similar products, only product within
the same product category. The international marked offers a wide variety of protein powders that support
the consumer with many nutritional proteins. It is a great product, but we don’t see any potential for this to
be a food source for undernourished poor people. Protein powders are produced synthetically and must be
available in big amounts to cover the daily needs of the inhabitants of an entire village and a new storage
must be delivered very often. It is impossible to deliver protein powder to all undernourished people
in the world, as there a too many (805 millions in
2012-2014
Source:
(Food and Agriculture Organization of the United Nations, 2014: Hunger Statistics.
(Link)
), and it would be very expensive.
Furthermore, protein powder needs to be dissolved in a liquid media, which is often insufficient for poor
people.
Our OneProt protein, which is produced in the Nutrition Generator, is produced by bacteria that can
reproduce themselves. A Nutrition Generator only needs to be delivered once, and will afterwards produce
protein and fat rich food, under consumption of cheap and easy accessible materials.
Marketing - our promises to the costumer
Nutrition Generator can supply the consumer with proteins and fats, food sources that all people in the
world need. Everyone can be a consumer of the product, and it is usable with and without electricity, which
gives the product multiple applications.
We promise our customers a sustainable product that has very low cost of operation by the use of
materials that are not degradable by humans and available all over the world.
Furthermore the use is safe, as no living bacteria will ever escape from the tank, and as the media is sterile
autoclaved before the product is eaten.
We see a great potential for Nutrition Generator, an easy usable and cheap product that can save many
lives.