Team:SDU-Denmark/Tour52

From 2014.igem.org

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<h3> The worlds opinion </h3>
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<h3>Ethics</h3>
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<h4>Outreach in Ghana</h4>
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<p>
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<span class="intro">By generating nutrition made</span> of bacteria our team pointed at contributing to the considerable task of
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providing accurate nutrient to third world countries. The contradiction between common opinion of how
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food is produced and of finding a solution on obtaining food in the future has been a key issue to our
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project. Furthermore, the ethical and social aspects to our project are decisive to include.<br><br>
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<span class="intro">This means that we</span> have considered what good research is. Good research includes the common opinion
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in society, and for this reason outreach in Ghana provided understanding of different standpoints to our
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project.<br><br>
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</p>
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<h4>Interview, Dr. Yaa Difie-Osei:</h4>
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<p>
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<span class="intro">Senior Lecturer in Biochemistry,</span> Dr. Yaa Difie-Osei (Dr. Yaa), agreed to meet with our team member, Anne,
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during her stay in the capital of Ghana Accra in August. The purpose was to talk about GMOs in relation
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to our Edible coli. The interview was held at the Department of Biochemistry, Cell and Molecular Biology
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at the University of Ghana, Legon. Dr. Yaa had previously worked at the university herself but was retired
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from her position as lecturer. Unlike most who retire due to many years of service, Dr. Yaa is still involved in
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the development of synthetic biology in Ghana as a member of the National Biosafety Committee of Ghana.
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The fact that Dr. Yaa has much experience regarding synthetic biology and at the same time is a member of
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the National Biosafety Committee means that her expertise relates brilliantly to our project.<br><br>
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<span class="intro">When Dr. Yaa heard</span> about our iGEM project she expressed great interest and there was a clear
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understanding or acknowledgement of the concepts of iGEM or both. Dr. Yaa spoke very passionately of
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GMOs and made it clear that GMOs would be an essential solution to malnutrition, which is a recurring
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motif in Ghana. As a member of the Safety Committee Dr. Yaa had recently contributed to the approval of
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four GMO projects in Ghana. The four GMO projects includes protein rich sweet potato and cotton with
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pesticides integrated into the genom (BT-cotton). The projects have got permits to do research but the research
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will be subject to strict rules concerning biosafety, management of risks in biochemistry and national
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<span class="sourceReference"> biosafety.</span>
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<span class="tooltip">
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  <span class="tooltipHeader">Source:</span>
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    A.A. Adenle et al.: Status of development, regulation and adoption of GM agriculture in Africa: Views and positions of stakeholder groups. Food Policy. 2013:43,159-166.
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<a href="http://www.sciencedirect.com/science/article/pii/S0306919213001346" target="_blank">(Link)</a></span><br><br>
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<span class="intro">Dr. Yaa Spoke of</span> GMO as an important step forward. The positive effects of GMOs relating to farmers as
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well as the general population of Ghana where among others as following:<br><br>
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Farmers:
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<ul>
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<li>Reduce of chemicals in farming</li>
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<li>Improvement of health</li>
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<li>Saving time for the farmers</li>
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<li>Saving tractor fuel, in relation to Green House Gasses.</li>
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</ul><br><br>
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General population:
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<ul>
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<li>Nutritional balance</li>
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<li>Prevention of children suffering from malnutrition</li>
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<li>Improvement of health</li>
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<li>Reduction of intolerance, as example lactose intolerance was given, where GMO could be
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accommodated by producing milk containing lactase, which is an enzyme one lacks when
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lactose
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<span class="sourceReference"> intolerance</span>
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<span class="tooltip">
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  <span class="tooltipHeader">Source:</span>
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    Swallow, D.M.: Genetics of Lactase Persistence and Lactoseintolerance.
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Annu.Rev.Genet,2003.37:197-219.
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<a href="http://www.annualreviews.org/doi/pdf/10.1146/annurev.genet.37.110801.143820" target="_blank">(Link)</a></span></li>
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</ul><br><br>
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<span class="intro">There is much focus</span> on the fact that child health has improved in Ghana due to the decrease in child
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mortality
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<span class="sourceReference"> rate,</span>
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<span class="tooltip">
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  <span class="tooltipHeader">Source:</span>
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    Child Mortality Estimates, 2014: Under-five mortality rate
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<a href="http://www.childmortality.org/index.php?r=site/graph&ID=GHA_Ghana" target="_blank">(Link)</a></span>
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although the nutritional status of children in Ghana still remains a
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<span class="sourceReference"> challenge.</span>
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<span class="tooltip">
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  <span class="tooltipHeader">Source:</span>
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    World Health Organization, 2014: Country Cooperation Strategy at a glance.
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<a href="http://www.who.int/countryfocus/cooperation_strategy/ccsbrief_gha_en.pdf?ua=1" target="_blank">(Link)</a></span><br><br>
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<span class="intro">By introducing GMOs this</span> issue could potentially be reduced. However, the ethical aspects of introducing
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GMOs as relief-aid for hunger or malnutrition or both must be subject to consideration, according to Dr.
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Yaa. Personally, Dr. Yaa did not think of GMO as ethically incorrect if the purpose was relief of hunger or
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malnutrition or both. However, it would be necessary to educate any population so they would have a basis
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of decision regarding the use of GMOs as a nutrition source.<br><br>
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<span class="intro">Dr. Yaa mentioned the</span> importance of considering indications for an idea of any genetically modified
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organism. The hypothetical GMO should have relevance in a way that promises improvement of lifestyle or
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brings good quality to something or both.<br><br>
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<span class="intro">Furthermore, it would be</span> necessary to demonstrate the safety of the GMO. This would include risk
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assessments such as inspection of the organism when separated from its natural surroundings. It would
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furthermore be crucial that the commercial releases were informative so that the consumers would receive
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the essential information.<br><br>
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Professor George Armah (Prof. Armah) was head of the Electron Microscopy & Histopathology department
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at the Nuguchi Memorial Institute for Medical Research, University of Ghana, Legon. Currently Prof. Armah
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is the Master of Commonwealth Hall, University of Ghana, Legon.<br><br>
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Prof. Armah has much expert knowledge about the health profile of the Ghanaians as well as the condition
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of life in Ghana. Therefore, Prof. Armah was an interesting scientist to interview in connection with
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applications of Edible coli in malnourished countries.<br><br>
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<span class="intro">Prof. Armah believed that</span> the Edible coli could have potential in Ghana. The main issue would be to
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introduce the product as a new source of nutrition. According to Prof. Armah it would be decisive whether
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the Edible coli could be included in the Ghanaian gastronomy. Prof. Armah proposed that a genetically
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modified nutrition source in combination with an already existing nutrition source would make the most
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sense. His argument was that it seemed unlikely to change the way people live. Therefore, GMOs should be
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incorporated into food such as sweet potato, rice etc.<br><br>
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Prof. Armah spoke of two important aspects of malnutrition in Ghana:
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<ol>
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<li>The spoilage of food was mentioned an issue in Ghana. Lack of food is not a problem in Ghana
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compared to the proportion of nutrient. Depending on the geographical location, the people eat
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differently. In the southern part of Ghana the population primarily eat fish and fufu. Fufu is a
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staple food made from the cassava plant and this is rich on carbohydrates. The population in the
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northern part of Ghana have lots of vegetables and chicken, and therefore they do not get the
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recommended ratio of omega fattyacids.</li>
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<li>The second issue Prof. Armah spoke of was tradition and cultural practices of Ghana. As mentioned,
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food available is different according to regions in Ghana. In addition to this, the different regions
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have different ingredients that they use for their traditional dishes. Furthermore, people act have
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different priority or tradition of daily diet or both.</li>
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</ol><br><br>
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<span class="intro">Prof. Armah clarified the</span> two aspects by giving examples from the northern part of Ghana. Traditionally
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children cannot eat eggs, which is a contradiction to the fact that children need good nutrition for proper development and
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<span class="sourceReference"> growth.</span>
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<span class="tooltip">
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  <span class="tooltipHeader">Source:</span>
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    The MAL-ED Network Investigators: The MAL-ED Study: A Multinational and Multidisciplinary Approach to
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Understand the Relationship Between Enteric Pathogens, Malnutrition, Gut Physiology, Physical Growth,
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Cognitive Development, and Immune Responses in Infants and Children Up to 2 Years of Age in Resource-
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Poor Environments. Clin Infect Dis,2014:59(4),193-206.
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<a href="http://cid.oxfordjournals.org/content/59/suppl_4/S193.long#sec-28" target="_blank">(Link)</a></span><br><br>
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The reason for this was that children become impertinent if they eat eggs.<br>
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Another example from the northern part of Ghana was that most men would rather sell a chicken instead
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of eating it. Instead, the men would choose to buy alcohol.<br><br>
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<span class="intro">Prof. Armah told about</span> the problems considering malnutrition as localized. Cultural and educational
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practices where mentioned as issues in relation to the application of GMOs. According to Prof. Armah the
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rural areas of Ghana did not take interest in synthetic biology due to the lack of education.<br><br>
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Objections to the use of synthetic biology did not have anything to do with religion or culture according
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to Prof. Armah. The culture and tradition in society would have the greatest influence on the population.
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Thereby GMOs might not be rejected based on a religious or social point of view or both. The resentment
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against synthetic biology would rather be on the basis on the fact that the population might not embrace a
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foreign initiative.
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</p>
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Revision as of 14:33, 14 October 2014