Team:SDU-Denmark/Tour27

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<h3> 1.1.1.3 - homoserine dehydrogenase</h3>
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<h3>1.1.1.3 - homoserine dehydrogenase</h3>
<h4>L-aspartate-4-semialdehyde + NAD(P)H+H<sup>+</sup> <font size="5">&#8652;</font> homoserine + NAD(P)<sup>+</sup> </h4><br>
<h4>L-aspartate-4-semialdehyde + NAD(P)H+H<sup>+</sup> <font size="5">&#8652;</font> homoserine + NAD(P)<sup>+</sup> </h4><br>
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<h5> Model submitted by SDU-Denmark 2014 </h5> <br>
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<h5>Model submitted by SDU-Denmark 2014 </h5> <br>
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<b> Notes/Assumption: </b> <br>
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<span class = intro>Notes/Assumption: </span> <br>
We do not include NAD(P)H+H<sup>+</sup> and NAD(P)<sup>+</sup> in the model. <br> <br>
We do not include NAD(P)H+H<sup>+</sup> and NAD(P)<sup>+</sup> in the model. <br> <br>
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<b> The reaction is on the form: </b> A <font size="5">&#8652;</font> B <br>
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<span class = intro>The reaction is on the form: </span> A <font size="5">&#8652;</font> B <br>
<b> A: </b> L-aspartate-4-semialdehyde <br>
<b> A: </b> L-aspartate-4-semialdehyde <br>
<b> B: </b> Homoserine <br> <br>
<b> B: </b> Homoserine <br> <br>
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<b> Rate function:</b>  <br>
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<span class = intro>Rate function:</span<br><br>
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<a href="https://2014.igem.org/Team:SDU-Denmark/Tour28"><img src="https://static.igem.org/mediawiki/2014/3/3c/SDU20141_1_1_3_example.PNG" width="265" height="54"></a> (click picture for copyable formula with constants inserted.)<br>
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<a href="https://2014.igem.org/Team:SDU-Denmark/Tour28"><img src="https://static.igem.org/mediawiki/2014/3/3c/SDU20141_1_1_3_example.PNG" width="265" height="54"></a> &nbsp; &nbsp;(<b>click picture</b> for copyable formula with constants inserted)<br><br>
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Back to Enzymes page: <a href="https://2014.igem.org/Team:SDU-Denmark/Tour25">Enzymes</a> <br>
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<span class = intro>Back to Enzymes page:</span> <a href="https://2014.igem.org/Team:SDU-Denmark/Tour25">Enzymes</a> <br>
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Back to modelling page: <a href="https://2014.igem.org/Team:SDU-Denmark/Tour24">Modelling</a>
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<span class = intro>Back to modelling page:</span> <a href="https://2014.igem.org/Team:SDU-Denmark/Tour24">Modelling</a>
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Latest revision as of 23:16, 17 October 2014

1.1.1.3 - homoserine dehydrogenase

L-aspartate-4-semialdehyde + NAD(P)H+H+ homoserine + NAD(P)+


Model submitted by SDU-Denmark 2014

Notes/Assumption:
We do not include NAD(P)H+H+ and NAD(P)+ in the model.

The reaction is on the form: A B
A: L-aspartate-4-semialdehyde
B: Homoserine

Rate function:

   (click picture for copyable formula with constants inserted)


Constant Value Comment Reference
Vmax,forward 2.8 Value obtained from Glycine Max Brenda
Vmax,reverse 0.24 Value obtained from Glycine Max Brenda
Km,A 0.17 Value obtained from E. coli Brenda
Km,B 0.013 Value obtained from E. coli Brenda


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