Team:Glasgow/Modeling
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- | < | + | <strong> Section 1: Modelling of Bacteria Random Walk </strong><br> |
+ | Firstly, we created a very basic 2D model of a flagella propelled bacterium. This was heavily based on the “random walk” model we mentioned previously, only we introduced a small degree of order, based on a more extensive and all-encompassing model created by Dillon, Fauci and Gaver in 1995.(link to paper?)DOI: 10.1006/jtbi.1995.0251 <br> | ||
+ | <br> | ||
+ | In order to simplify the model, we made a number of assumptions. These are:<br> | ||
+ | <ul> | ||
+ | <li>Tumbling is instantaneous</li> | ||
+ | <li>Chemotaxic gradient is not a factor</li> | ||
+ | <li>An E.coil cell can be represented as a sphere</li> | ||
+ | <li>Speed is constant (20ms<sup>-1</sup>) | ||
+ | </ul> | ||
+ | <br> | ||
+ | |||
+ | The movement of a bacteria through a medium is described thus:<br> | ||
+ | 1. The bacteria is moving at a random angle at a certain speed.<br> | ||
+ | 2. After a certain time (the “run” time), the bacteria reorientates itself (the “tumble”), and sets off at a different angle. This run time can be influenced by the chemotaxic gradient, if present | ||
+ | <br> | ||
+ | <img class="modelimage" src="https://static.igem.org/mediawiki/2014/4/49/GU_run_and_tumble.PNG"/> | ||
</div> | </div> |
Revision as of 14:33, 6 August 2014
Section 1: Modelling of Bacteria Random Walk
Firstly, we created a very basic 2D model of a flagella propelled bacterium. This was heavily based on the “random walk” model we mentioned previously, only we introduced a small degree of order, based on a more extensive and all-encompassing model created by Dillon, Fauci and Gaver in 1995.(link to paper?)DOI: 10.1006/jtbi.1995.0251
In order to simplify the model, we made a number of assumptions. These are:
The movement of a bacteria through a medium is described thus:
1. The bacteria is moving at a random angle at a certain speed.
2. After a certain time (the “run” time), the bacteria reorientates itself (the “tumble”), and sets off at a different angle. This run time can be influenced by the chemotaxic gradient, if present
Firstly, we created a very basic 2D model of a flagella propelled bacterium. This was heavily based on the “random walk” model we mentioned previously, only we introduced a small degree of order, based on a more extensive and all-encompassing model created by Dillon, Fauci and Gaver in 1995.(link to paper?)DOI: 10.1006/jtbi.1995.0251
In order to simplify the model, we made a number of assumptions. These are:
- Tumbling is instantaneous
- Chemotaxic gradient is not a factor
- An E.coil cell can be represented as a sphere
- Speed is constant (20ms-1)
The movement of a bacteria through a medium is described thus:
1. The bacteria is moving at a random angle at a certain speed.
2. After a certain time (the “run” time), the bacteria reorientates itself (the “tumble”), and sets off at a different angle. This run time can be influenced by the chemotaxic gradient, if present