Team:Waterloo

From 2014.igem.org

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<h2 class="centerUpper blueOnGrey" style="margin: 40px 2%;">Project Cornerstones</h2>
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<a href="https://2014.igem.org/Team:Waterloo/Deliver"><img src="https://static.igem.org/mediawiki/2014/9/98/Waterloo_deliver_icon.png" class="icon" /></a>  
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Revision as of 23:44, 17 October 2014

Waterloo iGem 2014 Team

Staphylocide

Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation

Problem

MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...

Solution

...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing in vivo and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.

Project Cornerstones

Explore the three cornerstones of this year's project: delivering the silencing in vivo using conjugation, silencing mecA expression using CRISPRi and sRNA and translating from the lab to the patients.