Team:Waterloo

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<h1>Staphylocide</h1>
<h1>Staphylocide</h1>
<h3 style="text-align: center">Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3>
<h3 style="text-align: center">Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3>
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<h2 class="centerUpper" style="background: #333; padding: 10px; color:#71CCE6;">Problem</h2>
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<h2 class="centerUpper blueOnGrey">Problem</h2>
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<p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p>
<p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p>
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<p>...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing <em>in vivo</em> and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.</p>
<p>...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing <em>in vivo</em> and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.</p>

Revision as of 22:13, 17 October 2014

Waterloo iGem 2014 Team

Staphylocide

Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation

Problem

MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...

Solution

...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing in vivo and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.

Project Cornerstones

Explore the three cornerstones of this year's project: delivering the silencing in vivo using conjugation, silencing mecA expression using CRISPRi and sRNA and translating from the lab to the patients.