Team:Glasgow

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Glasgow's 2014 iGEM project involves the creation of a new and hopefully very useful tool for synthetic biologists. With the aid of a genetic switch we will create a system that, in the presence of a given stimulus, will switch between one gene and another – a change that will persist in subsequent generations unless reversed. The switch is thus an integral part of the project. It is a site specific recombinase switch (φC31 integrase) isolated from the Streptomyces phage φC31. It flips a section of DNA, and a promoter, in order to turn off the expression of one gene section in favour of another.

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