"
Team:Glasgow/Modeling
From 2014.igem.org
(Difference between revisions)
Lowlight42 (Talk | contribs) |
Lowlight42 (Talk | contribs) |
||
| Line 16: | Line 16: | ||
#nochemo {position:absolute; | #nochemo {position:absolute; | ||
| - | top: | + | top:470px; |
left:25px; | left:25px; | ||
width:500px;} | width:500px;} | ||
#chemo {position:absolute; | #chemo {position:absolute; | ||
| - | top: | + | top:470px; |
right:25px; | right:25px; | ||
width:600px} | width:600px} | ||
Revision as of 15:02, 6 August 2014
 |
 |
 |
 |
|
Section 1: Modelling of Bacteria Random Walk
Firstly, we created a very basic 2D model of a flagella propelled bacterium. This was heavily based on the “random walk” model we mentioned previously, only we introduced a small degree of order, based on a more extensive and all-encompassing model created by Dillon, Fauci and Gaver in 1995.(link to paper?)DOI: 10.1006/jtbi.1995.0251
In order to simplify the model, we made a number of assumptions. These are:
The movement of a bacteria through a medium is described thus:
1. The bacteria is moving at a random angle at a certain speed.
2. After a certain time (the “run” time), the bacteria reorientates itself (the “tumble”),
and sets off at a different angle. This run time can be influenced by the chemotaxic gradient,
if present.
The images below describe how the run times are influenced: if the bacteria is on a path towards the "food", it is unlikely to change direction.
Firstly, we created a very basic 2D model of a flagella propelled bacterium. This was heavily based on the “random walk” model we mentioned previously, only we introduced a small degree of order, based on a more extensive and all-encompassing model created by Dillon, Fauci and Gaver in 1995.(link to paper?)DOI: 10.1006/jtbi.1995.0251
In order to simplify the model, we made a number of assumptions. These are:
- Tumbling is instantaneous
- Chemotaxic gradient is not a factor
- An E.coil cell can be represented as a sphere
- Speed is constant (20ms-1)
The movement of a bacteria through a medium is described thus:
1. The bacteria is moving at a random angle at a certain speed.
2. After a certain time (the “run” time), the bacteria reorientates itself (the “tumble”),
and sets off at a different angle. This run time can be influenced by the chemotaxic gradient,
if present.
The images below describe how the run times are influenced: if the bacteria is on a path towards the "food", it is unlikely to change direction.
