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Team:Heidelberg/Modeling
From 2014.igem.org
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<a href="/Team:Heidelberg/Modeling/Linker_Modeling" class="box" style="display:block; width:100%;"> | <a href="/Team:Heidelberg/Modeling/Linker_Modeling" class="box" style="display:block; width:100%;"> | ||
<h2><span>LINKER MODELING</span></h2> | <h2><span>LINKER MODELING</span></h2> | ||
| - | + | The design of linkers, which are essential for our intein-based circularization and assembly methods, is a complicated task. Here we employ structural modeling and statistical analyses to guide our linker experiments and their design. | |
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<a href="/Team:Heidelberg/Modeling/Enzyme_Modeling" class="box" style="display:block; width:100%;"> | <a href="/Team:Heidelberg/Modeling/Enzyme_Modeling" class="box" style="display:block; width:100%;"> | ||
| - | <h2><span> | + | <h2><span>ENZYME KINETICS MODELING</span></h2> |
| - | + | Based on over 1000 degradation curves of our circularized lysozyme variants, we tried to interpret the effect of linkers on protein thermostability. This was achieved by use of quantitative dynamical modeling. | |
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Latest revision as of 03:04, 18 October 2014
MODELING
– Quantitative insights
