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Team:Waterloo
From 2014.igem.org
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<h1>Staphylocide</h1> | <h1>Staphylocide</h1> | ||
| - | <h3 style="text-align: center"> | + | <h3 style="text-align: center">Delivery of an Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3> |
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<div class="anchor" id="view0" style="padding-top:0px;"> | <div class="anchor" id="view0" style="padding-top:0px;"> | ||
| - | <div style="padding-bottom:50px; min-height: 200px; margin-bottom: | + | <div style="padding-bottom:50px; min-height: 200px; margin-bottom: 40px;"> |
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<h2 class="centerUpper blueOnGrey">Problem</h2> | <h2 class="centerUpper blueOnGrey">Problem</h2> | ||
<img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/c/cc/Waterloo_mrsa_face.png" /> | <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/c/cc/Waterloo_mrsa_face.png" /> | ||
<p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p> | <p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p> | ||
</div> | </div> | ||
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<h2 class="centerUpper blueOnGrey">Solution</h2> | <h2 class="centerUpper blueOnGrey">Solution</h2> | ||
<img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/9/94/Waterloo_staphylocide_face.png" /> | <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/9/94/Waterloo_staphylocide_face.png" /> | ||
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| - | <h2 class="centerUpper blueOnGrey" style="margin: | + | <h2 class="centerUpper blueOnGrey" style="margin-left: 2%; margin-right: 2%; margin-top: 80;"">Project Cornerstones</h2> |
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<a href="https://2014.igem.org/Team:Waterloo/Deliver"><img src="https://static.igem.org/mediawiki/2014/9/98/Waterloo_deliver_icon.png" class="icon" /></a> | <a href="https://2014.igem.org/Team:Waterloo/Deliver"><img src="https://static.igem.org/mediawiki/2014/9/98/Waterloo_deliver_icon.png" class="icon" /></a> | ||
<a href="https://2014.igem.org/Team:Waterloo/Silence"><img src="https://static.igem.org/mediawiki/2014/9/9e/Waterloo_silence_icon.png" class="icon" /></a> | <a href="https://2014.igem.org/Team:Waterloo/Silence"><img src="https://static.igem.org/mediawiki/2014/9/9e/Waterloo_silence_icon.png" class="icon" /></a> | ||
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<div style="text-align: center; width: 90%; margin: auto;"><p>Explore the three cornerstones of this year's project: <a href="https://2014.igem.org/Team:Waterloo/Deliver">delivering</a> the silencing <em>in vivo</em> using conjugation, <a href="https://2014.igem.org/Team:Waterloo/Silence">silencing</a> <em>mecA</em> expression using CRISPRi and sRNA and <a href="https://2014.igem.org/Team:Waterloo/Translate">translating</a> from the lab to the patients.</p></div> | <div style="text-align: center; width: 90%; margin: auto;"><p>Explore the three cornerstones of this year's project: <a href="https://2014.igem.org/Team:Waterloo/Deliver">delivering</a> the silencing <em>in vivo</em> using conjugation, <a href="https://2014.igem.org/Team:Waterloo/Silence">silencing</a> <em>mecA</em> expression using CRISPRi and sRNA and <a href="https://2014.igem.org/Team:Waterloo/Translate">translating</a> from the lab to the patients.</p></div> | ||
| - | </div></div></div> | + | </div></div></div></div> |
Latest revision as of 02:33, 18 October 2014
Staphylocide
Delivery of an Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation
Problem
MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...
Solution
...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing in vivo and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.
Project Cornerstones
Explore the three cornerstones of this year's project: delivering the silencing in vivo using conjugation, silencing mecA expression using CRISPRi and sRNA and translating from the lab to the patients.
