Team:Waterloo

From 2014.igem.org

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<h1>Staphylocide</h1>
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<h3 style="text-align: center">Delivery of an Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3>
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<h1>Staphylocide</h1><br><br>
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  <h2 class="centerUpper blueOnGrey">Problem</h2>
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<h2 class="centerUpper">Solution</h2>
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  <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/c/cc/Waterloo_mrsa_face.png" />
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...and here enters Suzie ...YAY!<br>
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  <p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p>
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<h2 class="centerUpper">Problem</h2>
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  <h2 class="centerUpper blueOnGrey">Solution</h2>
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So here's what happened ...lalala ...and then he did this and that and the bacteria just went BAM! and nobody knew what to do and yeaaaa... <br>
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  <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/9/94/Waterloo_staphylocide_face.png" />
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  <p>...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing <em>in vivo</em> and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.</p>
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<p>&nbsp;</p>
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<h2 style="text-align: center">Project Cornerstones</h2>
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<h2 class="centerUpper blueOnGrey" style="margin-left: 2%; margin-right: 2%; margin-top: 80;"">Project Cornerstones</h2>
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<a href="https://2014.igem.org/Team:Waterloo/Deliver"><img src="https://static.igem.org/mediawiki/2014/9/98/Waterloo_deliver_icon.png" class="icon" /></a>  
<a href="https://2014.igem.org/Team:Waterloo/Deliver"><img src="https://static.igem.org/mediawiki/2014/9/98/Waterloo_deliver_icon.png" class="icon" /></a>  
<a href="https://2014.igem.org/Team:Waterloo/Silence"><img src="https://static.igem.org/mediawiki/2014/9/9e/Waterloo_silence_icon.png" class="icon" /></a>
<a href="https://2014.igem.org/Team:Waterloo/Silence"><img src="https://static.igem.org/mediawiki/2014/9/9e/Waterloo_silence_icon.png" class="icon" /></a>
<a href="https://2014.igem.org/Team:Waterloo/Translate"><img src="https://static.igem.org/mediawiki/2014/7/7e/Waterloo_translate_icon.png" class="icon" /></a>
<a href="https://2014.igem.org/Team:Waterloo/Translate"><img src="https://static.igem.org/mediawiki/2014/7/7e/Waterloo_translate_icon.png" class="icon" /></a>
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<div style="text-align: center; width: 90%; margin: auto;"><p>Explore the three cornerstones of this year's project: <a href="https://2014.igem.org/Team:Waterloo/Deliver">delivering</a> the silencing <em>in vivo</em> using conjugation, <a href="https://2014.igem.org/Team:Waterloo/Silence">silencing</a> <em>mecA</em> expression using CRISPRi and sRNA and <a href="https://2014.igem.org/Team:Waterloo/Translate">translating</a> from the lab to the patients.</p></div>
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Latest revision as of 02:33, 18 October 2014

Waterloo iGem 2014 Team

Staphylocide

Delivery of an Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation

Problem

MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...

Solution

...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing in vivo and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.

 

Project Cornerstones

Explore the three cornerstones of this year's project: delivering the silencing in vivo using conjugation, silencing mecA expression using CRISPRi and sRNA and translating from the lab to the patients.

Retrieved from "http://2014.igem.org/Team:Waterloo"