Team:Heidelberg/Modeling

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title=MODELING
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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:Heidelberg/Modeling&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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<a href="https://2014.igem.org/Team:Heidelberg"style="color:#000000">Home </a> </td>
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<a href="https://2014.igem.org/Team:Heidelberg/Team"style="color:#000000"> Team </a> </td>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=Heidelberg"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:Heidelberg/Project"style="color:#000000"> Project</a></td>
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<a href="https://2014.igem.org/Team:Heidelberg/Modeling"style="color:#000000"> Modeling</a></td>
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<a href="https://2014.igem.org/Team:Heidelberg/Attributions"style="color:#000000"> Attributions </a></td>
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<tr><td colspan="3"> <h3>Modeling</h3></td></tr>
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    <a href="/Team:Heidelberg/Modeling/Linker_Modeling" class="box" style="display:block; width:100%;">
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      <h2><span>LINKER MODELING</span></h2>
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      The design of linkers, which are essential for our intein-based circularization and assembly methods, is a complicated task. Here we employ structural modeling and statistical analyses to guide our linker experiments and their design.
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      <h2><span>ENZYME KINETICS MODELING</span></h2>
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      Based on over 1000 degradation curves of our circularized lysozyme variants, we tried to interpret the effect of linkers on protein thermostability. This was achieved by use of quantitative dynamical modeling.
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<p>If you choose to create a model during your project, please write about it here. Modeling is not an essential part of iGEM, but we encourage any and all teams to model some aspect of their project. See previous "Best Model" awards for more information.</p>
 
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Latest revision as of 03:04, 18 October 2014