Team:Waterloo

From 2014.igem.org

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<title>Waterloo iGem 2014 Team</title>
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<h1>Staphylocide</h1>
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<h3 style="text-align: center">Delivery of an Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation</h3>
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  <h2 class="centerUpper blueOnGrey">Problem</h2>
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  <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/c/cc/Waterloo_mrsa_face.png" />
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  <p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p>
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<div class="half-column floatRight">
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  <h2 class="centerUpper blueOnGrey">Solution</h2>
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  <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/9/94/Waterloo_staphylocide_face.png" />
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  <p>...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing <em>in vivo</em> and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.</p>
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<p>&nbsp;</p>
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<h2 class="centerUpper blueOnGrey" style="margin-left: 2%; margin-right: 2%; margin-top: 80;"">Project Cornerstones</h2>
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<a href="https://2014.igem.org/Team:Waterloo/Deliver"><img src="https://static.igem.org/mediawiki/2014/9/98/Waterloo_deliver_icon.png" class="icon" /></a>
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<a href="https://2014.igem.org/Team:Waterloo/Silence"><img src="https://static.igem.org/mediawiki/2014/9/9e/Waterloo_silence_icon.png" class="icon" /></a>
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<a href="https://2014.igem.org/Team:Waterloo/Translate"><img src="https://static.igem.org/mediawiki/2014/7/7e/Waterloo_translate_icon.png" class="icon" /></a>
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<div style="text-align: center; width: 90%; margin: auto;"><p>Explore the three cornerstones of this year's project: <a href="https://2014.igem.org/Team:Waterloo/Deliver">delivering</a> the silencing <em>in vivo</em> using conjugation, <a href="https://2014.igem.org/Team:Waterloo/Silence">silencing</a> <em>mecA</em> expression using CRISPRi and sRNA and <a href="https://2014.igem.org/Team:Waterloo/Translate">translating</a> from the lab to the patients.</p></div>
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<h1 >WELCOME TO iGEM 2014! </h1>
 
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<p>Your team has been approved and you are ready to start the iGEM season!
 
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
 
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:Waterloo&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
 
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<a href="https://2014.igem.org/Team:Waterloo"style="color:#000000">Home </a> </td>
 
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<a href="https://2014.igem.org/Team:Waterloo/Team"style="color:#000000"> Team </a> </td>
 
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<a href="https://igem.org/Team.cgi?year=2014&team_name=Waterloo"style="color:#000000"> Official Team Profile </a></td>
 
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<a href="https://2014.igem.org/Team:Waterloo/Project"style="color:#000000"> Project</a></td>
 
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<a href="https://2014.igem.org/Team:Waterloo/Modeling"style="color:#000000"> Modeling</a></td>
 
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<a href="https://2014.igem.org/Team:Waterloo/Attributions"style="color:#000000"> Attributions </a></td>
 
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<p> Please be sure to keep these links, your audience will want to find your: </p>
 
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<li><a href="https://2014.igem.org/Team:Waterloo">Home</a> </li>
 
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<li><a href="https://2014.igem.org/Team:Waterloo/Team">Team</a> </li>
 
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=Waterloo">Official Team Profile</a> </li>
 
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<li><a href="https://2014.igem.org/Team:Waterloo/Project">Project</a> </li>
 
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<li><a href="https://2014.igem.org/Team:Waterloo/Modeling">Modeling</a> </li>
 
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<li><a href="https://2014.igem.org/Team:Waterloo/Notebook">Notebook</a> </li>
 
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<li><a href="https://2014.igem.org/Team:Waterloo/Safety">Safety</a> </li>
 
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<p>There are a few wiki requirements teams must follow:</p>
 
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<li>All pages, images and files must be hosted on the <a href ="https://2014.igem.org/Special:Upload">  2014.igem.org server</a>. </li>
 
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<li>All pages must be created under the team’s name space.</li>
 
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<li>As part of your documentation, keep the links from the menu to the left. </li>
 
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<li>Do not use flash in wiki code. </li>
 
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<li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
 
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<p>Visit the <a href="https://2014.igem.org/Wiki_How-To"> Wiki How To page </a> for a complete list of requirements, tips and other useful information. </p>
 
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<tr><td colspan="3" > <h3> Tips  </h3></td></tr>
 
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<p>We are currently working on providing teams with some easy to use design templates.
 
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
 
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
 
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
 
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
 
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
 
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
 
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a>  lists. </p>
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Latest revision as of 02:33, 18 October 2014

Waterloo iGem 2014 Team

Staphylocide

Delivery of an Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation

Problem

MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...

Solution

...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing in vivo and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.

 

Project Cornerstones

Explore the three cornerstones of this year's project: delivering the silencing in vivo using conjugation, silencing mecA expression using CRISPRi and sRNA and translating from the lab to the patients.