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Team:Waterloo
From 2014.igem.org
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<h2 class="centerUpper blueOnGrey">Problem</h2> | <h2 class="centerUpper blueOnGrey">Problem</h2> | ||
<img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/c/cc/Waterloo_mrsa_face.png" /> | <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/c/cc/Waterloo_mrsa_face.png" /> | ||
<p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p> | <p>MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...</p> | ||
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<h2 class="centerUpper blueOnGrey">Solution</h2> | <h2 class="centerUpper blueOnGrey">Solution</h2> | ||
<img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/9/94/Waterloo_staphylocide_face.png" /> | <img class="smallIcon floatRight" src="https://static.igem.org/mediawiki/2014/9/94/Waterloo_staphylocide_face.png" /> | ||
Revision as of 22:40, 17 October 2014
Staphylocide
Delivering Antibiotic Resistance Gene Silencing Mechanism to a MRSA Population using Bacterial Conjugation
Problem
MRSA is sweeping the nation, an antibiotic-resistant scourge migrating from hospitals into communities. We need a hero to fight it and Waterloo iGEM has designed a synthetic bacterium that just might do the trick...
Solution
...Staphylocide! Staphylocide delivers antibiotic resistance gene silencing in vivo and could one day be incorporated into a treatment that would help doctors defeat MRSA once and for all.
Project Cornerstones
Explore the three cornerstones of this year's project: delivering the silencing in vivo using conjugation, silencing mecA expression using CRISPRi and sRNA and translating from the lab to the patients.
