Team:Calgary/Project/BsDetector/TargetDiseases

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<h1>Target Diseases</h1>
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<p>Our pathogen detection system consists of two collections of interconnected genes (operons) placed inside various regions (loci) of the <Bacillus Subtilis> chromosome. The first operon is designated the "reporter" and consists of a constitutive promoter (<i>Pveg</i>), a ribosome binding site, a repressible operator(<i>C2P22</i>), and a chromophore (<i>LacZ</i>). Our "reporter" operon works in conjunction with our "repressor" operon, which consists of the same promoter ribomsome binding site, and a repressor gene designed to negate the function of aforementioned operator (<i>C2P22</i>). In addition, the repressor gene will be flanked by sequences homologous to a target sequence within our intended pathogen(s). </p>
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Revision as of 22:35, 27 September 2014

Target Diseases

Our pathogen detection system consists of two collections of interconnected genes (operons) placed inside various regions (loci) of the chromosome. The first operon is designated the "reporter" and consists of a constitutive promoter (Pveg), a ribosome binding site, a repressible operator(C2P22), and a chromophore (LacZ). Our "reporter" operon works in conjunction with our "repressor" operon, which consists of the same promoter ribomsome binding site, and a repressor gene designed to negate the function of aforementioned operator (C2P22). In addition, the repressor gene will be flanked by sequences homologous to a target sequence within our intended pathogen(s).