Team:UI-Indonesia/Project

From 2014.igem.org

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<h2>Background</h2>
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<p>Biofilms are dense packaged microbial cells grow on surface or inert and sorround themselves with secreted polymers. Microbial infection estimated 60-80% of microbial infection in the body. According to National Instutute of Health, more than 65% of all microbial infection caused by biofilms<a href="#"><sup>1</sup></a>. National Institute of Allergy and Infectious Diseases estimates two million healthcare-associated infections (HAIs), most of which associated with biofilms, happened in the United States annually, approximately 100,000 death (NIAID, 2010).<br>
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Bacteria inside the biofilm is equipped with high resistance towards antibiotics and host immune defenses. In fact, the biofilm is immune towards acid so that it can protect the bacteria from stomach acid. When ignored, the existence of this biofilm can cause severe illness and worsen diarrhea, thus we need specific and effective management.  High dose of antibiotic can be an alternative way but higher dose of antibiotic has been given for case with broad resistant , it is not the right answer to fight biofilm. Excessive dose of antibiotic will increase the probability of resistant bacteria (Hall-Stoodley L, Costerton J, & Stoodley P, 2004).
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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:UI-Indonesia/Project&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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<a href="https://2014.igem.org/Team:UI-Indonesia"style="color:#000000">Home </a> </td>
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<a href="https://2014.igem.org/Team:UI-Indonesia/Team"style="color:#000000"> Team </a> </td>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=UI-Indonesia"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:UI-Indonesia/Project"style="color:#000000"> Project</a></td>
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<a href="https://2014.igem.org/Team:UI-Indonesia/Modeling"style="color:#000000"> Modeling</a></td>
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<a href="https://2014.igem.org/Team:UI-Indonesia/Attributions"style="color:#000000"> Attributions </a></td>
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<tr><td > <h3> Project Description </h3></td>
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<p>Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs) </p>
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<h3>References </h3>
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iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you though about your project and what works inspired you. </p>
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<p> You can use these subtopics to further explain your project</p>
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<li>Overall project summary</li>
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<li>Project Details</li>
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<li>Materials and Methods</li>
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It's important for teams to describe all the creativity that goes into an iGEM project, along with all the great ideas your team will come up with over the course of your work.  
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It's also important to clearly describe your achievements so that judges will know what you tried to do and where you succeeded. Please write your project page such that what you achieved is easy to distinguish from what you attempted.
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Revision as of 15:34, 17 October 2014

Background

Biofilms are dense packaged microbial cells grow on surface or inert and sorround themselves with secreted polymers. Microbial infection estimated 60-80% of microbial infection in the body. According to National Instutute of Health, more than 65% of all microbial infection caused by biofilms1. National Institute of Allergy and Infectious Diseases estimates two million healthcare-associated infections (HAIs), most of which associated with biofilms, happened in the United States annually, approximately 100,000 death (NIAID, 2010).
Bacteria inside the biofilm is equipped with high resistance towards antibiotics and host immune defenses. In fact, the biofilm is immune towards acid so that it can protect the bacteria from stomach acid. When ignored, the existence of this biofilm can cause severe illness and worsen diarrhea, thus we need specific and effective management. High dose of antibiotic can be an alternative way but higher dose of antibiotic has been given for case with broad resistant , it is not the right answer to fight biofilm. Excessive dose of antibiotic will increase the probability of resistant bacteria (Hall-Stoodley L, Costerton J, & Stoodley P, 2004).

Retrieved from "http://2014.igem.org/Team:UI-Indonesia/Project"