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Team:Oxford
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<a href="mailto:oxfordigem@bioch.ox.ac.uk" target="_blank" style="background-image: none;"><img src="https://static.igem.org/mediawiki/2014/3/35/OxigemIconmail.png" style="width:100%;" /></a> | <a href="mailto:oxfordigem@bioch.ox.ac.uk" target="_blank" style="background-image: none;"><img src="https://static.igem.org/mediawiki/2014/3/35/OxigemIconmail.png" style="width:100%;" /></a> | ||
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| - | + | <div id="abstract" style="position: absolute; width:0%; height:100%; top: 0%; left: 50%; background-color: #f5f5f5; z-index:10; border-radius:15px;"> | |
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<a href="#"><img id="x" src="https://static.igem.org/mediawiki/2014/7/7f/Oxigemx.png" onclick="hideabstract()" style="position:absolute;opacity:0.6;right:0.9%;top:1.5%;display:none;" /></a> | <a href="#"><img id="x" src="https://static.igem.org/mediawiki/2014/7/7f/Oxigemx.png" onclick="hideabstract()" style="position:absolute;opacity:0.6;right:0.9%;top:1.5%;display:none;" /></a> | ||
<div id="abstract2" style="position:absolute; display:none; colour:white; width:90%;height:92%;margin-left:5%;margin-right:5%;margin-top:2%;overflow-y:scroll;overflow-x:visible;"> | <div id="abstract2" style="position:absolute; display:none; colour:white; width:90%;height:92%;margin-left:5%;margin-right:5%;margin-top:2%;overflow-y:scroll;overflow-x:visible;"> | ||
| + | <div class="inner" style="width:100%;margin-left:auto;margin-right:auto;height:100%;position:absolute;"> | ||
| + | <img class="DCMationgif" style="margin-left:5%;" src="https://static.igem.org/mediawiki/2014/8/81/DCMation1.png" width="90%" align="middle" alt="" onclick='javascript:(this.src=="https://static.igem.org/mediawiki/2014/8/81/DCMation1.png"?this.src="https://static.igem.org/mediawiki/2014/e/e2/OxigemDCMationgif.gif":"")' /> | ||
| + | University of Oxford’s first iGEM team presents: DCMation, a novel bioremediation approach whose applications are limited only by the versatility of bacterial metabolism. OxiGEM are tackling environmental pollution by developing a user-friendly device for the detection & degradation of the hazardous yet indispensable solvent dichloromethane (DCM), to illustrate. | ||
| + | <br> | ||
| + | Inspired by the DCM degradation pathway of <font style="font-style: italic;">M. extorquens</font> DM4, our project is driven and refined by the dialogue between modelling simulations and experimental data. Bioremediation is optimised by expressing the DCM degrading system in host strains, along with microcompartments to accelerate the reaction and minimise toxic intermediates. Our biosensor is tuned to our characterisation and improvements of the catalytic efficiency of the system, while incorporation of the bacteria into novel diffusion-limiting biopolymeric beads ensures safe and rapid degradation. | ||
| + | <br> | ||
| + | This all-round modular design and scalability make DCMation ideal for extension to the disposal of many harmful substances. Explore our wiki for more! | ||
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| + | <img src="https://static.igem.org/mediawiki/2014/7/78/OxigemBiosensor1.png" style="position:absolute; width:106%;margin-left:-3%;margin-top:-10%;" /> | ||
| + | <a href="#"><img id="next1" src="https://static.igem.org/mediawiki/2014/7/73/OxigemNext.png" style="position:absolute;width:3%;margin-left:101.5%;margin-top:27%;" /></a> | ||
| - | + | <a href="https://2014.igem.org/Team:Oxford/biosensor"><img class="zero" src="https://static.igem.org/mediawiki/2014/a/af/Oxigem1.0.jpg" style="width:90%;margin-left:5%;margin-top:28%;" /></a> | |
| - | < | + | <a href="https://2014.igem.org/Team:Oxford/biosensor_characterisation"><img class="one" src="https://static.igem.org/mediawiki/2014/f/f8/Oxigem1.1.jpg" style="width:90%;margin-left:5%;margin-top:0.2%;" /></a> |
| - | + | <a href="https://2014.igem.org/Team:Oxford/biosensor_construction"><img class="two" src="https://static.igem.org/mediawiki/2014/8/84/Oxigem1.2.jpg" style="width:90%;margin-left:5%;margin-top:0.2%;" /></a> | |
| - | < | + | <a href="https://2014.igem.org/Team:Oxford/biosensor_optimisation"><img class="three" src="https://static.igem.org/mediawiki/2014/d/df/Oxigem1.3.jpg" style="width:90%;margin-left:5%;margin-top:0.2%;" /></a> |
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| + | <img src="https://static.igem.org/mediawiki/2014/e/e8/OxigemBioremediation1.png" style="position:absolute; width:106%;margin-left:-3%;margin-top:-10%;" /> | ||
| + | <a href="#"><img id="next2" src="https://static.igem.org/mediawiki/2014/7/73/OxigemNext.png" style="position:absolute;width:3%;margin-left:101.5%;margin-top:27%;" /></a> | ||
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| + | <a href="https://2014.igem.org/Team:Oxford/bioremediation"><img class="one" src="https://static.igem.org/mediawiki/2014/d/d3/Oxigem2.0.jpg" style="width:90%;margin-left:5%;margin-top:28%;" /></a> | ||
| + | <a href="https://2014.igem.org/Team:Oxford/how_much_can_we_degrade?"><img class="two" src="https://static.igem.org/mediawiki/2014/2/21/Oxigem2.1.jpg" style="width:90%;margin-left:5%;margin-top:0.2%;" /></a> | ||
| + | <a href="https://2014.igem.org/Team:Oxford/what_are_microcompartments?"><img class="two" src="https://static.igem.org/mediawiki/2014/b/bb/Oxigem2.2.jpg" style="width:90%;margin-left:5%;margin-top:0.2%;" /></a> | ||
</div> | </div> | ||
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| + | <img src="https://static.igem.org/mediawiki/2014/1/1b/OxigemRealisation1.png" style="position:absolute; width:106%;margin-left:-3%;margin-top:-10%;" /> | ||
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| + | <a href="https://2014.igem.org/Team:Oxford/biosensor_realisation"><img class="one" src="https://static.igem.org/mediawiki/2014/f/f6/Oxigem3.1.jpg" style="width:90%;margin-left:5%;margin-top:28%;" /></a> | ||
| + | <a href="https://2014.igem.org/Team:Oxford/realisation_bioremediation"><img class="two" src="https://static.igem.org/mediawiki/2014/1/1b/Oxigem3.2.jpg" style="width:90%;margin-left:5%;margin-top:0.2%;" /></a> | ||
| + | <a href="https://2014.igem.org/Team:Oxford/biopolymer_containment"><img class="three" src="https://static.igem.org/mediawiki/2014/9/91/Oxigem3.3.jpg" style="width:90%;margin-left:5%;margin-top:0.2%;" /></a> | ||
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<img id="down" src="https://static.igem.org/mediawiki/2014/1/1c/OxigemDown.png" style="position: absolute; width:65%; top: 0; left: 17%;"> | <img id="down" src="https://static.igem.org/mediawiki/2014/1/1c/OxigemDown.png" style="position: absolute; width:65%; top: 0; left: 17%;"> | ||
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<div class="Heading" style="top: 17%; left: 27%; width:40%;" onmouseover="Partsbig(this)" onmouseout= | <div class="Heading" style="top: 17%; left: 27%; width:40%;" onmouseover="Partsbig(this)" onmouseout= | ||
"Partsnormal(this)" border="0"> | "Partsnormal(this)" border="0"> | ||
| Line 180: | Line 176: | ||
"https://static.igem.org/mediawiki/2014/f/fa/OxigemParts.png" style="width: 100%;"></a> | "https://static.igem.org/mediawiki/2014/f/fa/OxigemParts.png" style="width: 100%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="top: 45%; left: 14%; width:33.5%;" onmouseover="Medalsbig(this)" onmouseout= | <div class="Heading" style="top: 45%; left: 14%; width:33.5%;" onmouseover="Medalsbig(this)" onmouseout= | ||
"Medalsnormal(this)" border="0"> | "Medalsnormal(this)" border="0"> | ||
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</div> | </div> | ||
| - | + | <div id="Interlabwrap" onClick="InterlabHide()" | |
style="background-color: rgba(0,0,0,0.1); position: fixed; top:0; left: 0; right: 0; bottom: 0; display:none"> | style="background-color: rgba(0,0,0,0.1); position: fixed; top:0; left: 0; right: 0; bottom: 0; display:none"> | ||
<div class="Heading" id="Interlabpopup" style= | <div class="Heading" id="Interlabpopup" style= | ||
"left:72%; width:0%; position:absolute; margin-top:19%;"> | "left:72%; width:0%; position:absolute; margin-top:19%;"> | ||
<img src="https://static.igem.org/mediawiki/2014/d/df/OxigemInterlabbg.png" style="width: 100%;"> | <img src="https://static.igem.org/mediawiki/2014/d/df/OxigemInterlabbg.png" style="width: 100%;"> | ||
| - | |||
<div class="Heading" style="top: 63.5%; left: 39%; width:38%;" onmouseover="Subheadingbig(this)" onmouseout= | <div class="Heading" style="top: 63.5%; left: 39%; width:38%;" onmouseover="Subheadingbig(this)" onmouseout= | ||
"Subheadingnormal(this)" border="0"> | "Subheadingnormal(this)" border="0"> | ||
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"https://static.igem.org/mediawiki/2014/1/11/OxigemIDevices.png" style="width: 100%;"></a> | "https://static.igem.org/mediawiki/2014/1/11/OxigemIDevices.png" style="width: 100%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="top: 22.5%; left: 17.3%; width:20.5%;" onmouseover="IMeasurementbig(this)" onmouseout= | <div class="Heading" style="top: 22.5%; left: 17.3%; width:20.5%;" onmouseover="IMeasurementbig(this)" onmouseout= | ||
"IMeasurementnormal(this)" border="0"> | "IMeasurementnormal(this)" border="0"> | ||
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"https://static.igem.org/mediawiki/2014/6/6d/OxigemIMeasurement.png" style="width: 100%;"></a> | "https://static.igem.org/mediawiki/2014/6/6d/OxigemIMeasurement.png" style="width: 100%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="top: 17%; left: 49.5%; width:34%;" onmouseover="IResultsbig(this)" onmouseout= | <div class="Heading" style="top: 17%; left: 49.5%; width:34%;" onmouseover="IResultsbig(this)" onmouseout= | ||
"IResultsnormal(this)" border="0"> | "IResultsnormal(this)" border="0"> | ||
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</div> | </div> | ||
</div> | </div> | ||
| - | + | </div> | |
| - | + | <div id="iGEMcommwrap" onClick="iGEMcommHide()" | |
style="background-color: rgba(0,0,0,0.1); position: fixed; top:0; left: 0; right: 0; bottom: 0; display:none"> | style="background-color: rgba(0,0,0,0.1); position: fixed; top:0; left: 0; right: 0; bottom: 0; display:none"> | ||
<div class="Heading" id="iGEMcommpopup" style= | <div class="Heading" id="iGEMcommpopup" style= | ||
"left:25%; width:0%; position:absolute; margin-top:19%;"> | "left:25%; width:0%; position:absolute; margin-top:19%;"> | ||
<img src="https://static.igem.org/mediawiki/2014/e/e9/OxigemiGEMcommbg.png" style="width: 100%;"> | <img src="https://static.igem.org/mediawiki/2014/e/e9/OxigemiGEMcommbg.png" style="width: 100%;"> | ||
| - | + | <div class="Heading" style="top: 61.1%; left: 34.3%; width:43%;" onmouseover="Collabbig(this)" onmouseout= | |
| - | <div class="Heading" style="top: | + | |
"Collabnormal(this)" border="0"> | "Collabnormal(this)" border="0"> | ||
| - | <a href="https://2014.igem.org/Team:Oxford/ | + | <a href="https://2014.igem.org/Team:Oxford/alternatives_to_microcompartments"><img src= |
"https://static.igem.org/mediawiki/2014/0/0c/OxigemCollaboration.png" style="width: 100%;"></a> | "https://static.igem.org/mediawiki/2014/0/0c/OxigemCollaboration.png" style="width: 100%;"></a> | ||
</div> | </div> | ||
| - | + | <div class="Heading" style="top: 17.5%; left: 54.5%; width:29.5%;" onmouseover="Eventsbig(this)" onmouseout= | |
| - | <div class="Heading" style="top: | + | |
"Eventsnormal(this)" border="0"> | "Eventsnormal(this)" border="0"> | ||
<a href="https://2014.igem.org/Team:Oxford/Events"><img src= | <a href="https://2014.igem.org/Team:Oxford/Events"><img src= | ||
"https://static.igem.org/mediawiki/2014/a/af/OxigemEvents.png" style="width: 100%;"></a> | "https://static.igem.org/mediawiki/2014/a/af/OxigemEvents.png" style="width: 100%;"></a> | ||
</div> | </div> | ||
| - | + | <div class="Heading" style="top: 24.5%; left: 16.5%; width:17%;" onmouseover="iGEMEuropebig(this)" onmouseout= | |
| - | <div class="Heading" style="top: | + | |
"iGEMEuropenormal(this)" border="0"> | "iGEMEuropenormal(this)" border="0"> | ||
| - | <a href="https://2014.igem.org/Team:Oxford/ | + | <a href="https://2014.igem.org/Team:Oxford/P&P_igem_europe"><img src= |
"https://static.igem.org/mediawiki/2014/4/49/OxigemiGEMEurope.png" style="width: 100%;"></a> | "https://static.igem.org/mediawiki/2014/4/49/OxigemiGEMEurope.png" style="width: 100%;"></a> | ||
</div> | </div> | ||
</div> | </div> | ||
| - | + | </div> | |
| - | + | ||
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| + | <div style="position:fixed;bottom:2%;left:5%;width:90%;height:7%;background-color:#f5f5f5;border-radius:25px;opacity:0.6;"> | ||
<div class="Heading" style="position:fixed;bottom:3.8%; left: 7%; width:7%;max-height:6%;"> | <div class="Heading" style="position:fixed;bottom:3.8%; left: 7%; width:7%;max-height:6%;"> | ||
| - | <a href="http://www.bbsrc.ac.uk/home/home.aspx"><img src="https://static.igem.org/mediawiki/2014/3/3e/BBSRC.png" | + | <a href="http://www.bbsrc.ac.uk/home/home.aspx" target="_blank"><img src="https://static.igem.org/mediawiki/2014/3/3e/BBSRC.png" |
style="width: 110%;"></a> | style="width: 110%;"></a> | ||
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| - | |||
<div class="Heading" style="position:fixed;bottom:3.8%; left: 16.5%; width:10%;max-height:6%;"> | <div class="Heading" style="position:fixed;bottom:3.8%; left: 16.5%; width:10%;max-height:6%;"> | ||
| - | <a href="http://www.biochemistry.org"><img src="https://static.igem.org/mediawiki/2014/7/75/BS.png" | + | <a href="http://www.biochemistry.org" target="_blank"><img src="https://static.igem.org/mediawiki/2014/7/75/BS.png" |
style="width: 110%;"></a> | style="width: 110%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="position:fixed;bottom:3.4%; left: 29%; width:9%;max-height:6%;"> | <div class="Heading" style="position:fixed;bottom:3.4%; left: 29%; width:9%;max-height:6%;"> | ||
| - | <a href="http://www.sgm.ac.uk"><img src="https://static.igem.org/mediawiki/2014/2/20/SGM.png" | + | <a href="http://www.sgm.ac.uk" target="_blank"><img src="https://static.igem.org/mediawiki/2014/2/20/SGM.png" |
style="width: 110%;"></a> | style="width: 110%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="position:fixed;bottom:4.4%; left: 40.4%; width:10%;max-height:6%;"> | <div class="Heading" style="position:fixed;bottom:4.4%; left: 40.4%; width:10%;max-height:6%;"> | ||
| - | <a href="http://www.wellcome.ac.uk"><img src="https://static.igem.org/mediawiki/2014/4/4c/WT.png" | + | <a href="http://www.wellcome.ac.uk" target="_blank"><img src="https://static.igem.org/mediawiki/2014/4/4c/WT.png" |
style="width: 110%;"></a> | style="width: 110%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="position:fixed;bottom:2.7%; left: 53.5%; width:6.5%;max-height:6%;"> | <div class="Heading" style="position:fixed;bottom:2.7%; left: 53.5%; width:6.5%;max-height:6%;"> | ||
| - | <a href="http://www.deskgen.com/"><img src="https://static.igem.org/mediawiki/2014/6/65/Oxfordigem_deskgen.png" | + | <a href="http://www.deskgen.com/" target="_blank"><img src="https://static.igem.org/mediawiki/2014/6/65/Oxfordigem_deskgen.png" |
style="width: 110%;"></a> | style="width: 110%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="position:fixed;bottom:2.5%; left: 62.7%; width:9.5%;max-height:6%;"> | <div class="Heading" style="position:fixed;bottom:2.5%; left: 62.7%; width:9.5%;max-height:6%;"> | ||
| - | <a href="http://www.bioch.ox.ac.uk/"><img src="https://static.igem.org/mediawiki/2014/2/20/Oxfordigem_dept.png" | + | <a href="http://www.bioch.ox.ac.uk/" target="_blank"><img src="https://static.igem.org/mediawiki/2014/2/20/Oxfordigem_dept.png" |
style="width: 110%;"></a> | style="width: 110%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="position:fixed;bottom:3%; left: 75%; width:7%;max-height:6%;"> | <div class="Heading" style="position:fixed;bottom:3%; left: 75%; width:7%;max-height:6%;"> | ||
| - | <a href="http://www.neb.com/"><img src="https://static.igem.org/mediawiki/2014/ | + | <a href="http://www.neb.com/" target="_blank"><img src="https://static.igem.org/mediawiki/2014/b/b1/OxigemNeb_logo.png" |
style="width: 110%;"></a> | style="width: 110%;"></a> | ||
</div> | </div> | ||
| - | |||
<div class="Heading" style="position:fixed;bottom:3%; left: 84%; width:8%;max-height:6%;"> | <div class="Heading" style="position:fixed;bottom:3%; left: 84%; width:8%;max-height:6%;"> | ||
| - | <a href="http://www.snapgene.com/"><img src="https://static.igem.org/mediawiki/2014/f/ff/Oxfordigem_snapgene.png" | + | <a href="http://www.snapgene.com/" target="_blank"><img src="https://static.igem.org/mediawiki/2014/f/ff/Oxfordigem_snapgene.png" |
style="width: 110%;"></a> | style="width: 110%;"></a> | ||
</div> | </div> | ||
| - | </div> | + | </div> |
</div> | </div> | ||
Latest revision as of 19:15, 2 June 2015
University of Oxford’s first iGEM team presents: DCMation, a novel bioremediation approach whose applications are limited only by the versatility of bacterial metabolism. OxiGEM are tackling environmental pollution by developing a user-friendly device for the detection & degradation of the hazardous yet indispensable solvent dichloromethane (DCM), to illustrate.
