Team:ITESM-Guadalajara

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for the iGEM competition of 2014">
 
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Profile</td>
 
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    <h1><b1><font size=20>Bio San</font></b></h1>
 
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    <p align=justify>
 
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    Chitosan is a polysaccharide found in abundance in shrimp
 
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shell. The current extraction methods involve the use of strong
 
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acids and alkalis, these substances are dangerous wastes that can
 
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compromise the integrity of soil and water where they are
 
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disposed.
 
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    <br><br>Due to its stability and biocompatibility, chitosan
 
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has been widely used in pharmaceutical, food, and cosmetic
 
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industries, among many others. The Chitosan global market has an
 
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estimated value of $20 billion USD. Particularly, the
 
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pharmaceutical industry represents on average 1.2% of total GDP
 
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in Mexico and has grown at a 10% rate since 2008.
 
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    <br><br>Therefore, it is imperative to develop a new and
 
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efficient extraction process, that is also eco-friendly. We’ve
 
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developed a new process that consists in the pretreatment of
 
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shrimp shells, followed by a fermentation in which it is
 
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demineralized and deproteinized by B. subtilis. Finally, it goes
 
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through a deacetylation process in a fermentation performed by
 
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our genetically modified E. coli strain. This modified bacterium
 
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contains 6 different enzymes that are found naturally in
 
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microorganisms that are capable of cutting and deacetylating
 
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chitin for the generation of chitosan. The action of these
 
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enzymes and a careful temperature treatment will allow us to
 
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generate chitosan with a 90% deacetylation degree. This
 
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deacetylation
 
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degree is the required one by the pharmaceutical industry, our
 
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target market.
 
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image:url('https://fbcdn-sphotos-f-a.akamaihd.net/hphotos-ak-
 
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xap1/v/t1.0-9/10590698_707932682595933_7087832657777301608_n.jpg?
 
-
 
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oh=f533b9d73439a56b107c0f3ec16122e7&oe=5468A3B7&__gda__=141610583
 
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5_ac3f7c4c68248971a4a538ede6c4d157')"></div>
 
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        <table class="team-member-footer">
 
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          <tr><td>Nombre</td></tr>
 
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        </table>
 
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      </div>
 
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      <div class="team-member-container row2"
 
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data="https://fbcdn-sphotos-e-a.akamaihd.net/hphotos-ak-
 
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xap1/v/t1.0-9/165694_10150142314796000_7339784_n.jpg?
 
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oh=c4599b843494e5e3e6ea043f4274c2b1&oe=545BAECC&__gda__=141589910
 
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8_2f1d374b729bee21393bdf1255ed6c9f" hover="https://fbcdn-
 
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sphotos-d-a.akamaihd.net/hphotos-ak-frc1/v/t1.0-
 
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9/2470_1096828574662_3159_n.jpg?
 
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oh=b1a3493fb69aa27197041f4bf73d2191&oe=546392E8&__gda__=141654299
 
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5_5148dea6508c832a52f86a4dbf92a38f">
 
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        <div class="team-member-photo" style="background-
 
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image:url('https://fbcdn-sphotos-e-a.akamaihd.net/hphotos-ak-
 
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xap1/v/t1.0-9/165694_10150142314796000_7339784_n.jpg?
 
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oh=c4599b843494e5e3e6ea043f4274c2b1&oe=545BAECC&__gda__=141589910
 
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8_2f1d374b729bee21393bdf1255ed6c9f')"></div>
 
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        <table class="team-member-footer">
 
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          <tr><td>Luis</td></tr>
 
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        </table>
 
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      </div>
 
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      <div class="team-member-container row2">
 
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        <div class="team-member-photo" style="background-
 
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image:url('https://fbcdn-sphotos-c-a.akamaihd.net/hphotos-ak-
 
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xfa1/v/t1.0-9/10665779_707932092595992_2156750832361780655_n.jpg?
 
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-
oh=1c5d1d6c1b2b3c4afc9f4039b025ab6d&oe=546E6D67&__gda__=141701665
 
-
 
-
7_9ddd60c7dab12c1483b649b5a8139f7a')"></div>
 
-
        <table class="team-member-footer">
 
-
          <tr><td>Nombre</td></tr>
 
-
        </table>
 
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      </div>
 
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      <div class="team-member-container row2">
 
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        <div class="team-member-photo" style="background-
 
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image:url('https://fbcdn-sphotos-c-a.akamaihd.net/hphotos-ak-
 
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xfa1/v/t1.0-9/10665779_707932092595992_2156750832361780655_n.jpg?
 
-
 
-
oh=1c5d1d6c1b2b3c4afc9f4039b025ab6d&oe=546E6D67&__gda__=141701665
 
-
 
-
7_9ddd60c7dab12c1483b649b5a8139f7a')"></div>
 
-
        <table class="team-member-footer">
 
-
          <tr><td>Nombre</td></tr>
 
-
        </table>
 
-
      </div>
 
-
 
-
      <div class="team-member-container row2">
 
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        <div class="team-member-photo" style="background-
 
-
 
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image:url('https://fbcdn-sphotos-c-a.akamaihd.net/hphotos-ak-
 
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xfa1/v/t1.0-9/10665779_707932092595992_2156750832361780655_n.jpg?
 
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-
oh=1c5d1d6c1b2b3c4afc9f4039b025ab6d&oe=546E6D67&__gda__=141701665
 
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-
7_9ddd60c7dab12c1483b649b5a8139f7a')"></div>
 
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        <table class="team-member-footer">
 
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          <tr><td>Nombre</td></tr>
 
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        </table>
 
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      </div>
 
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    </div>
 
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  </div>
 
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  <div id="teamprofile" class="container">
 
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    Team Profile section
 
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  </div>
 
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  <div id="project" class="container">
 
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    Project section
 
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  </div>
 
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  <div id="parts" class="container">
 
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    Parts section
 
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  </div>
 
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  <div id="modeling" class="container">
 
-
    Modeling section
 
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  </div>
 
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  <div id="notebook" class="container">
 
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    Notebook section
 
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  </div>
 
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  <div id="safety" class="container">
 
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    Safety section
 
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  </div>
 
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  <div id="attributions" class="container">
 
-
    Attributions section
 
-
  </div>
 
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<p style="color:#E7E7E7"> <a
 
-
 
-
href="https://2014.igem.org/wiki/index.php?title=Team:ITESM-
 
-
 
-
Guadalajara&action=edit"style="color:#190718"> Click here  to
 
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edit this page!</a> </p>
 
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</body>
 
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</html>
 

Revision as of 05:23, 5 September 2014