Team:HZAU-China/Circuit

After describing the biological processes and choosing a set of empirical parameters, we want to simulate our designed processing modules. Before the simulation, we characterized some promoters to estimate the promoter strength, which will sometimes influence the cell's state directly. To take the intrinsic noise into consideration, we simulate the stochastic time course trajectories of the state of a chemical reaction network using Gillespie algorithm (Gillespie, 2001). We will analysis our two designs respectively.

Figure 7: Deterministic simulation of design 1. The state versus time is simulated by scanning the moment of rewiring from 100 min to 900 min. The interval of the transient state we set is 20 min

Figure 8: Stochastic simulation of design 1. The parameter we used is the same as the deterministic model. The simulation is achieved by standard stochastic simulation algorithm (Direct method).