Team:ETH Zurich/modeling/int

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The parameter fitting is based on Bonnet's paper<sup>[[Team:ETH_Zurich/project/references|[9]]]</sup>. Their experimental setup is different from ours. However, they experimentally retrieve a transfer function between aTc and Bxb1 switching rate. Here is the figure of interest in our case.
The parameter fitting is based on Bonnet's paper<sup>[[Team:ETH_Zurich/project/references|[9]]]</sup>. Their experimental setup is different from ours. However, they experimentally retrieve a transfer function between aTc and Bxb1 switching rate. Here is the figure of interest in our case.
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[[File:ETH Zurich Bonnet S4.jpg|center|800px|thumb|Transfer function from aTc to Bxb1. The experimental data corresponds to the points. They fitted this data with their own model. Supplementary figure S4 of Bonnet's paper ''Amplifying Genetic Logic Gates''<sup>[[Team:ETH_Zurich/project/references|[9]]]</sup>]]
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[[File:ETH Zurich Bonnet S4.jpg|center|600px|thumb|Transfer function from aTc to Bxb1. The experimental data corresponds to the points. They fitted this data with their own model. Supplementary figure S4 of Bonnet's paper ''Amplifying Genetic Logic Gates''<sup>[[Team:ETH_Zurich/project/references|[9]]]</sup>]]
We do the same modeling steps, as for the [https://2014.igem.org/Team:ETH_Zurich/modeling/int#Characterization:_KSABxb1 previous characterization].Thus, we obtain the following set of differential equations:$$\begin{align*}
We do the same modeling steps, as for the [https://2014.igem.org/Team:ETH_Zurich/modeling/int#Characterization:_KSABxb1 previous characterization].Thus, we obtain the following set of differential equations:$$\begin{align*}

Revision as of 09:08, 13 October 2014

iGEM ETH Zurich 2014