Team:Dundee

From 2014.igem.org

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<link href="https://2014.igem.org/Team:Dundee/css/homepage?action=raw&ctype=text/css" rel="stylesheet">     
<link href="https://2014.igem.org/Team:Dundee/css/homepage?action=raw&ctype=text/css" rel="stylesheet">     
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             <div class="modal-header">
             <div class="modal-header">
         <button type="button" class="close" data-dismiss="modal" aria-hidden="true" id="closeNote">&times;</button>
         <button type="button" class="close" data-dismiss="modal" aria-hidden="true" id="closeNote">&times;</button>
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         <h4 class="modal-title" id="myModalLabel">Welcome to Dundee's 2014 Wiki</h4>
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         <h4 class="modal-title" id="myModalLabel">Welcome to Dundee's 2014 Wiki (<b>Site Information</b>)</h4>
       </div>           
       </div>           
                  
                  
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   <div class="tab-pane active" id="ab">
   <div class="tab-pane active" id="ab">
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   Cystic Fibrosis is a genetic disease that results in the accumulation of thick mucus in the epithelial linings of the entire body, particularly the respiratory tract. Over the course of a patient’s life the mucus-lined lung epithelium becomes repeatedly infected with pathogenic bacteria that stimulate an immune response, leading to inflammation, tissue damage, and ultimately, respiratory failure.   
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   Cystic Fibrosis is a genetic disease that results in the accumulation of thick mucus in the epithelial linings of the entire body, particularly the respiratory tract. Over the course of a patient’s life, the mucus-lined lung epithelium becomes repeatedly infected with pathogenic bacteria that stimulate an immune response; leading to inflammation, tissue damage, and ultimately, respiratory failure.   
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The microflora of the Cystic Fibrosis lung changes over time. In childhood, the major coloniser is Staphylococcus aureus, but as the patient matures other bacterial pathogens infect. The later-dominating pathogens, Pseudomonas aeruginosa and Burkholderia cepacia, are very difficult to eradicate and are associated with chronic decline in lung function. Burkholderia is so infectious, that patients have to be isolated from one another, and can be denied lung transplants due to the difficulty of eradication this bacterium.  
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The microflora of the Cystic Fibrosis lung changes over time. In childhood, the major coloniser is <i>Staphylococcus aureus</i>, but as the patient matures other bacterial pathogens infect. The later-dominating pathogens, <i>Pseudomonas aeruginosa</i> and <i>Burkholderia cepacia</i>, are very difficult to eradicate and are associated with chronic decline in lung function. <i>Burkholderia</i> is so infectious that patients have to be isolated from one another, and can be denied lung transplants due to the persistence of this bacterium.  
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The Dundee 2014 iGEM project is focused on designing and testing a device that will rapidly and non-invasively identify the bacteria colonising a Cystic Fibrosis patient. Three biosensors will be developed that recognise external signal molecules produced by key bacteria, all of which are known to be in sputum samples of Cystic Fibrosis patients. A quinolone signal (PQS) is produced by Pseudomonas aeruginosa, a Diffusible Signal Factor (DSF) is produced by Stenotrophomonas maltophilia, an organism that is also associated with cystic fibrosis lung infection in adults, and BDSF is a related, but chemically distinct molecule that is produced by Burkholderia cepacia.  
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The Dundee 2014 iGEM project is focused on designing and testing a device that will rapidly and non-invasively identify the bacteria colonising a Cystic Fibrosis patient. Three biosensors will be developed that recognise external signal molecules produced by key bacteria, all of which are known to be in sputum samples of Cystic Fibrosis patients. A quinolone signal (PQS) is produced by <i>Pseudomonas aeruginosa</i>, a Diffusible Signal Factor (DSF) is produced by <i>Stenotrophomonas maltophilia</i>, an organism that is also associated with Cystic Fibrosis lung infection in adults, and BDSF is a related, but chemically distinct molecule that is produced by <i>Burkholderia cepacia</i>.  
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Read this again by clicking on the board!       
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Read this again by clicking on <b>Site Information</b> in the navigation bar!       
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       <br>
       <br>
       <a href="#" class="thumbnail">
       <a href="#" class="thumbnail">
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         <img src="https://static.igem.org/mediawiki/2014/5/5e/Board.png"  
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         <img src="https://static.igem.org/mediawiki/2014/c/c2/Weeboarddun.png"  
         alt="Generic placeholder thumbnail">
         alt="Generic placeholder thumbnail">
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           <div class="col-sm-9 col-md-9">
           <div class="col-sm-9 col-md-9">
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     <h3>School</h3>  
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     <h3>Bulletin Board (Policy & Practice)</h3>  
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        Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nulla ullamcorper eu eros ultricies rutrum. Quisque varius, mi et commodo ullamcorper, lorem lorem feugiat mauris, quis bibendum libero arcu sit amet odio. Quisque in sodales felis. Nam sagittis augue dui, sed interdum elit eleifend quis. Vivamus luctus mauris quis ligula tempus, a pretium diam pulvinar. Nullam consectetur, purus sit amet porttitor porttitor, velit diam commodo quam, eget eleifend lorem est vitae nunc. Sed ac tortor ut velit vulputate cursus in et dolor.
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    Come look at the poster explaining how we involved the local and national Cystic Fibrosis community in our project, how we listened to people on the front line of the disease and how they affected our project.
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       </div>
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           <div class="col-sm-9 col-md-9">
           <div class="col-sm-9 col-md-9">
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     <h3>School</h3>  
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     <h3>School (Project)</h3>  
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         Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nulla ullamcorper eu eros ultricies rutrum. Quisque varius, mi et commodo ullamcorper, lorem lorem feugiat mauris, quis bibendum libero arcu sit amet odio. Quisque in sodales felis. Nam sagittis augue dui, sed interdum elit eleifend quis. Vivamus luctus mauris quis ligula tempus, a pretium diam pulvinar. Nullam consectetur, purus sit amet porttitor porttitor, velit diam commodo quam, eget eleifend lorem est vitae nunc. Sed ac tortor ut velit vulputate cursus in et dolor.
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      Come in and learn about all the parts that make The Lung Ranger. The lab work that we carried out over the   
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         summer is explained here in detail, along with the modelling and implementation.  
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<div class="col-sm-9 col-md-9">     
<div class="col-sm-9 col-md-9">     
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<h3>Library</h3>  
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<h3>Library (Log Book)</h3>  
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         Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nulla ullamcorper eu eros ultricies rutrum. Quisque varius, mi et commodo ullamcorper, lorem lorem feugiat mauris, quis bibendum libero arcu sit amet odio. Quisque in sodales felis. Nam sagittis augue dui, sed interdum elit eleifend quis. Vivamus luctus mauris quis ligula tempus, a pretium diam pulvinar. Nullam consectetur, purus sit amet porttitor porttitor, velit diam commodo quam, eget eleifend lorem est vitae nunc. Sed ac tortor ut velit vulputate cursus in et dolor.
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         Read about the experience the team has had over the summer. A week by week description of our work, how we carried out that work and some photos of our time together.
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<div class="col-sm-9 col-md-9">
<div class="col-sm-9 col-md-9">
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  <h3>Saloon</h3>  
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  <h3>Saloon (iGEM community)</h3>  
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        Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nulla ullamcorper eu eros ultricies rutrum. Quisque varius, mi et commodo ullamcorper, lorem lorem feugiat mauris, quis bibendum libero arcu sit amet odio. Quisque in sodales felis. Nam sagittis augue dui, sed interdum elit eleifend quis. Vivamus luctus mauris quis ligula tempus, a pretium diam pulvinar. Nullam consectetur, purus sit amet porttitor porttitor, velit diam commodo quam, eget eleifend lorem est vitae nunc. Sed ac tortor ut velit vulputate cursus in et dolor.
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Come on in, take a seat and learn how we have interacted with the larger iGEM community. Who the team are, who helped them and how we helped others.
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</div>
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      <a href="#" class="center">
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        <img  class="img-responsive"  src="https://static.igem.org/mediawiki/2014/e/ea/DunEastbio.png" />                             
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    </a>
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EASTBIO - the BBSRC East of Scotland Bioscience Doctoral Training Partnership - is a partnership between the Universities of Aberdeen, Dundee, Edinburgh and St Andrews; the Scottish Universities Life Sciences Alliance; and the Scottish Universities Physics Alliance. The DTP scheme will provide students with excellent cross-disciplinary research training in line with the current BBSRC strategy for research support and training.
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             if(id == "school")
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             if(id == "board")
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                $("#boardSpk").css({"opacity":"1"});
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            else if(id == "school")
             {
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                 $("#schoolSpk").css({"opacity":"1"});  
                 $("#schoolSpk").css({"opacity":"1"});  
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var board = paper.image("https://static.igem.org/mediawiki/2014/5/5e/Board.png", -271, 560, 150, 140);     
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var board = paper.image("https://static.igem.org/mediawiki/2014/c/c2/Weeboarddun.png", -271, 560, 150, 140);     
board.node.setAttribute("class","detail");  
board.node.setAttribute("class","detail");  
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board.node.addEventListener("click", function(){$("#welcomeNote").modal(); }, false);  
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board.node.setAttribute("id","board");
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board.node.addEventListener("click", function(){location.assign("https://2014.igem.org/Team:Dundee/inside/board")}, false);
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var boardSpk = paper.image("https://static.igem.org/mediawiki/2014/d/da/Bboardblurb.png",-310,290,230,288);  
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boardSpk.node.setAttribute("class","speech");   
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boardSpk.node.setAttribute("id","boardSpk");
var school = paper.image("https://static.igem.org/mediawiki/2014/a/ac/School.png",30,230,300,500);         
var school = paper.image("https://static.igem.org/mediawiki/2014/a/ac/School.png",30,230,300,500);         
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school.node.addEventListener("click", function(){location.assign("https://2014.igem.org/Team:Dundee/inside/school")}, false);   
school.node.addEventListener("click", function(){location.assign("https://2014.igem.org/Team:Dundee/inside/school")}, false);   
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var schoolSpk = paper.image("https://static.igem.org/mediawiki/2014/0/00/Speach.png",250,200,300,150);   
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var schoolSpk = paper.image("https://static.igem.org/mediawiki/2014/f/ff/Schoolblurb.png",-50,10,230,288);   
schoolSpk.node.setAttribute("class","speech");  
schoolSpk.node.setAttribute("class","speech");  
schoolSpk.node.setAttribute("id","schoolSpk");   
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library.node.addEventListener("click", function(){location.assign("https://2014.igem.org/Team:Dundee/inside/library")}, false);
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var librarySpk = paper.image("https://static.igem.org/mediawiki/2014/0/00/Speach.png",600,200,300,150);  
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var librarySpk = paper.image("https://static.igem.org/mediawiki/2014/e/e6/Libraryblurb.png",370,70,230,288);  
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librarySpk.node.setAttribute("class","speech");     
librarySpk.node.setAttribute("id","librarySpk");     
librarySpk.node.setAttribute("id","librarySpk");     
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saloon.node.setAttribute("class","detail");  
saloon.node.setAttribute("class","detail");  
saloon.node.setAttribute("id","saloon");  
saloon.node.setAttribute("id","saloon");  
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saloon.node.addEventListener("click", function(){location.assign("https://2014.igem.org/Team:Dundee/inside/saloon")}, false);
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var saloonSpk = paper.image("https://static.igem.org/mediawiki/2014/0/00/Speach.png",950,200,300,150);  
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var saloonSpk = paper.image("https://static.igem.org/mediawiki/2014/6/62/Saloonblurb.png",750,60,230,288);  
saloonSpk.node.setAttribute("class","speech");     
saloonSpk.node.setAttribute("class","speech");     
saloonSpk.node.setAttribute("id","saloonSpk");       
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var t =paper.text(180, 150, "School"); 
 
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var t =paper.text(480, 150, "Library"); 
 
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var t =paper.text(840, 150, "Saloon"); 
 
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}
}
   
   
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$( "#info" ).click( function() {
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  $("#welcomeNote").modal();
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});
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var outL = [     
var outL = [     
      
      

Latest revision as of 22:47, 17 October 2014

Dundee 2014