Team:Dundee

From 2014.igem.org

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The microflora of the Cystic Fibrosis lung changes over time. In childhood, the major coloniser is <i>Staphylococcus aureus</i>, but as the patient matures other bacterial pathogens infect. The later-dominating pathogens, <i>Pseudomonas aeruginosa</i> and <i>Burkholderia cepacia</i>, are very difficult to eradicate and are associated with chronic decline in lung function. <i>Burkholderia</i> is so infectious, that patients have to be isolated from one another, and can be denied lung transplants due to the persistance of this bacterium.  
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The microflora of the Cystic Fibrosis lung changes over time. In childhood, the major coloniser is <i>Staphylococcus aureus</i>, but as the patient matures other bacterial pathogens infect. The later-dominating pathogens, <i>Pseudomonas aeruginosa</i> and <i>Burkholderia cepacia</i>, are very difficult to eradicate and are associated with chronic decline in lung function. <i>Burkholderia</i> is so infectious, that patients have to be isolated from one another, and can be denied lung transplants due to the persistence of this bacterium.  
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Revision as of 10:20, 12 October 2014

Dundee 2014