Team:Aachen/TestBench

From 2014.igem.org

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Our biological approach
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In order to detect the pathogens fast, specifically and inexpensively we are building sensor cells to detect these pathogens. These sensor cells can identify pathogens in very low concentration by responsing to specific extracellular molecules either secreted by or displayed on the pathogens. These molecules trigger a fast fluorescence response which will be measured by our device.
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Aou can follow our molecular approach in more detail by checking out our
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<a href="https://2014.igem.org/Team:Aachen/Labbook">Biological Part/Labbook</a>
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The device
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The devices
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Revision as of 13:12, 13 May 2014

Welcome to the Teamwiki of the iGEM Aachen in 2014!

Cellock Holmes - a case of identity

Pathogens on solid surfaces in places where good hygiene is crucial pose a serious threat, since – even after cleaning – these can still be present in dangerous amounts. This is demonstrated by the high number of 3.2 million patients each year that have to be treated due to in the health sector acquired infections. And 37000 of those infections end deadly. The EU estimates that at least 20-30% of those cases would be preventable with an intensive hygiene program. However, for a more effective control these respective pathogens have to be identified.

We are developing a system that makes this possible. We are constructing a device with which pathogens can be detected easily, efficiently, effectively and less expensively by utilising genetically modified cells. We focus on a fast response time coupled with an automated analysis.

Our project is not only applicable to the detection of pathogens but we are looking to develop it further into a platform for a general 2D detection of nearly any cell or substance.




Our biological approach

In order to detect the pathogens fast, specifically and inexpensively we are building sensor cells to detect these pathogens. These sensor cells can identify pathogens in very low concentration by responsing to specific extracellular molecules either secreted by or displayed on the pathogens. These molecules trigger a fast fluorescence response which will be measured by our device.

Aou can follow our molecular approach in more detail by checking out our Biological Part/Labbook

The device

The devices

Our