Team:Hong Kong HKUST/riboregulator
From 2014.igem.org
Project Riboregulator Abstract
Regulatory RNAs are RNAs that regulate biological processes on genetic and metabolic levels, and their importance has been established through the discoveries including those of RNA interference (RNAi) and long noncoding RNAs (lncRNA). The elucidation of their mechanism has enabled their reverse engineering, transforming them into versatile tools in synthetic biology.
Given its size, "Project Riboregulator" is expected to take more than just a summer to complete. Thus at the moment of wiki freeze, information available here is bound to be limited. However, the project will continue on well after the Giant Jamboree. Information will be continuously and regularly updated, and because of its nature, "Project Riboregulator" is not part of our work for competing awards of any kind or in any year, but rather, a tribute to the Part Registry and iGEM community alone. |
CR and TA riboregulator system
Artificial cis-repressing and trans-activating riboregulator system was introduced to the iGEM community by Isaacs in 2005. The riboregulator system as a whole acts to regulate translation at the RNA level. One component of the system, crRNA, which contains a cis-repressing sequence at the 5' of the RBS, the RBS, and the gene of interest. |