Team:UCL/Humans/Collab

Universidade Nova de Lisboa - Martins Lab (to also include photo of their lab holding up Goodbye AzoDye logo)

The Microbial & Enzyme Technology Lab led by Dr Lígia O. Martins at the Universidade Nova de Lisboa is one of the world leaders in bioremediation with microorganisms and enzymes. Their paper titled 'Synergistic action of azoreductase and laccase leads to maximal decolourization and detoxification of model dye-containing wastewaters' [1] was the fundamental inspiration for our Goodbye AzoDye project. We are truly grateful for their initial support and guidance, and for sending us the following plasmids for our experiments:

pAzoR containing the FMN-dependent NADH-azoreductase 1 gene. [2]
pCotA containing the Spore Coat Protein Laccase gene. [3]
p1B6 containing the mutant FMN-dependent NADH-azoreductase 1 gene [4]
pBsDyp containing the Dye Decolourising Peroxidase BSU38260 gene. [4]
pPpDyp containing the Dye Decolourising Peroxidase PP_3248 gene.[4]

UCL Igem Bioprocess Team visits Godfrey Kyazze, a Lecturer in Bioprocess Technology at University of Westminster

Considering the complex and novel nature of scientific practices in synthetic biology there is a need to look at adapted forms of governance that deal with processes of innovation in a reflexive manner. This is seen as necessary in order to devise policies that can accommodate a sustainable development of the emerging technology within society. Considering the environmental risks to which they are ascribed, policy frameworks ought to engender effective governance that seeks to foster good science, not to hamper it. It also recognises that good science goes hand in hand with open, clear, transparent regulation to ensure both trust and accountability. Another prominent feature of synthetic biology is its ‘cross-borderness’, in addition to the embedded scientific uncertainty. It simultaneously crosses the borders of scientific disciplines, industrial sectors, and geopolitical areas. Considering the transboundary and uncertain nature of this emerging technology it might be interesting to look at how policies are being developed within the framework of transnational governance. Some views support the idea that synthetic biology policies should not only be regulated from a top down perspective through governments, but that non-governmental stakeholders and organisations should be able to engage in self-regulation. The transboundary – and transnational nature of synthetic biology practices makes it pertinent to examine biosecurity and sustainable innovation discourses at the level of transnational governance structures such as iGEM. The latter holds a series of promising characteristics with regard to innovative regulatory frameworks.