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Team:Caltech/Notebook
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<b><a href='Notebook'>Overview</a></b><br><br> | <b><a href='Notebook'>Overview</a></b><br><br> | ||
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| - | <h1>Project Overview</h1> | + | <h1> Project Overview </h1> |
<p>Our project was split into 3 subprojects: AgrBDCA signal reception, FsrABC signal reception, and Ligand export systems.</p> | <p>Our project was split into 3 subprojects: AgrBDCA signal reception, FsrABC signal reception, and Ligand export systems.</p> | ||
| - | < | + | <h4>AgrBDCA Signal Reception</h4> |
AgrBDCA is a quorum sensing system found to regulate virulence factors in Staphylococcus Aurea. (sp?) In this system, agrC and agrA function as a histidine kinase receptor and a response regulator respectively. | AgrBDCA is a quorum sensing system found to regulate virulence factors in Staphylococcus Aurea. (sp?) In this system, agrC and agrA function as a histidine kinase receptor and a response regulator respectively. | ||
| - | < | + | <h4>FsrABC Signal Reception</h54> |
FsrABC is another quorum sensing system found to regulate virulence factors in Entereococcus Faecialis (sp?). In this system, FsrC and FsrA function as histidine kinase receptor and response regulator respectively. FsrB is a membrane protein that is processed to form a cyclic 11-amino-acid polypeptide <!-- add a tag here that brings you down to Ligand export systems section -->(see Ligand Export Systems). | FsrABC is another quorum sensing system found to regulate virulence factors in Entereococcus Faecialis (sp?). In this system, FsrC and FsrA function as histidine kinase receptor and response regulator respectively. FsrB is a membrane protein that is processed to form a cyclic 11-amino-acid polypeptide <!-- add a tag here that brings you down to Ligand export systems section -->(see Ligand Export Systems). | ||
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With the AgrBDCA system, it is believed that agrB is a membrane protein that exports and modifies a short polypeptide sequence into a polypeptide ligand to be bound by agrC, the histidine kinase receptor. | With the AgrBDCA system, it is believed that agrB is a membrane protein that exports and modifies a short polypeptide sequence into a polypeptide ligand to be bound by agrC, the histidine kinase receptor. | ||
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Revision as of 18:42, 3 July 2014
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