Team:Heidelberg
From 2014.igem.org
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<h2 class="align-right" style="font-size: 40px;">come DISCOVER the MECHANISM of SPLIT INTEINS</h2><br><br> | <h2 class="align-right" style="font-size: 40px;">come DISCOVER the MECHANISM of SPLIT INTEINS</h2><br><br> | ||
- | <div class="col-lg-6"> | + | <div class="col-lg-6 normal-medium-text"> |
- | <p>Inteins excise themselves out of proteins and in doing so the remaining flanking parts are irreversibly joined</p> | + | <p class=""><span class="larger">Inteins excise themselves out of proteins and in doing so the remaining flanking parts are irreversibly joined</span></p> |
- | <p>– an effective mechanism to circularize proteins.</p> | + | <p><span class="larger">– an effective mechanism to circularize proteins.</span></p> |
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<p class="normal-medium-text align-right">But messing with protein structure can be disastrous,<br><span class="medium-text">you can only win with good MODELING.</span></p><br><br> | <p class="normal-medium-text align-right">But messing with protein structure can be disastrous,<br><span class="medium-text">you can only win with good MODELING.</span></p><br><br> | ||
<p class="normal-medium-text"><span>Find out the <span class="bold">EXCITING THEORY</span><br>behind <span class="bold">RIGID LINKERS</span> and their <span class="bold">ANGLES</span></span></p> | <p class="normal-medium-text"><span>Find out the <span class="bold">EXCITING THEORY</span><br>behind <span class="bold">RIGID LINKERS</span> and their <span class="bold">ANGLES</span></span></p> | ||
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<div class="col-md-4 col-md-push-8 col-md-offset-0 col-xs-offset-3 col-xs-6" style="z-index:5;"> | <div class="col-md-4 col-md-push-8 col-md-offset-0 col-xs-offset-3 col-xs-6" style="z-index:5;"> | ||
- | <img class="img-responsive" src="/wiki/images/a/a6/Heidelberg_Project_Dnmt1.png" | + | <img class="img-responsive" src="/wiki/images/a/a6/Heidelberg_Project_Dnmt1.png"> |
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<div class="col-md-8 col-md-pull-4 col-xs-12"> | <div class="col-md-8 col-md-pull-4 col-xs-12"> | ||
- | <h1 class=" | + | <h1 class="large-text">Our Application:</h1> |
- | <h1 class="dark-grey-text large-text" style="text-align: right;">circular <span class="red-text">heat-stable</span><br>DNA-methyltransferase</h1> | + | <h1 class="dark-grey-text large-text" style="text-align: right;"><span class="medium-large-text">circular <span class="red-text">heat-stable</span></span><br>DNA-methyltransferase</h1> |
- | <p class=" | + | <br><br><p><span class="larger">Wouldn´t it be great to amplify DNA preserving the encoded epigenetic information?</span></p> |
- | <p class=" | + | <p><span class="larger">See here an ENTIRELY NEW way of performing PCR with a <span class="red-text">heat stable</span> methyltransferase!</span></p> |
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- | <h2 class="medium-text align- | + | <h2 class="normal-medium-text align-right">One more thing.<br>Inteins are capable of mush more!</h2> |
- | <h1 class=" | + | <h1 class="medium-large-text align-right bold">We show you the world of</h1> |
- | <h1 class=" | + | <h1 class="medium-text align-right red-text bold" style=" |
- | <p class="align-right | + | font-size: 41px; |
- | <p class="align-right | + | ">post-translational MODIFICATIONS</h1><br><br> |
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+ | <p class="align-right "><span class="larger">We created an INTEIN TOOLBOX so you can easily modify your protein in a standardized way.</span></p> | ||
+ | <p class="align-right"><span class="larger">Take a look at our <a href="/Team:Heidelberg/Parts/RFC">RFC</a></span></p> | ||
+ | <p class="align-right"><span class="larger">Explore all our tools!</span></p> | ||
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Revision as of 16:14, 15 October 2014