Team:UI-Indonesia/Team/IHVCB-UI

From 2014.igem.org

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<h2>Background</h2>
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<h2>Institute of Human Virology and Cancer Biology Universitas Indonesia</h2>
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<p>Biofilms are dense packaged microbial cells grow on surface or inert and sorround themselves with secreted polymers. Microbial infection estimated 60-80% of microbial infection in the body. According to National Instutute of Health, more than 65% of all microbial infection caused by biofilms<a href="#"><sup>[1]</sup></a>. National Institute of Allergy and Infectious Diseases estimates two million healthcare-associated infections (HAIs), most of which associated with biofilms, happened in the United States annually, approximately 100,000 death<a href="#"><sup>[2]</sup></a>.
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<p>Institute of Human Virology and Cancer Biology Universitas Indonesia (IHVCB) is one of the few laboratory equipped with biosafety level 3 equipment in Indonesia. Maintained as one of the best and one of the center for diagnostic study of Human Immunodeficiency Virus that has mutated and resistant from drugs (multiple drug or even extreme drug resistance) in Indonesia, has teached us a lot of things about biosafety and biosecurity.
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<br>The lab which located on the eight floor of IASTH building, Salemba 4, Central Jakarta, also focuses on education by accepting undergraduates, master, and even postgraduates students to study inside.</p>
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Bacteria inside the biofilm is equipped with high resistance towards antibiotics and host immune defenses. In fact, the biofilm is immune towards acid so that it can protect the bacteria from stomach acid. When ignored, the existence of this biofilm can cause severe illness and worsen diarrhea, thus we need specific and effective management.  High dose of antibiotic can be an alternative way but  higher dose of antibiotic has been given for case with broad resistant , it is not the right answer to fight biofilm. Excessive dose of antibiotic will increase the probability of resistant bacteria<a href="#"><sup>[3]</sup></a>.</p>
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Revision as of 22:26, 17 October 2014

Institute of Human Virology and Cancer Biology Universitas Indonesia

Institute of Human Virology and Cancer Biology Universitas Indonesia (IHVCB) is one of the few laboratory equipped with biosafety level 3 equipment in Indonesia. Maintained as one of the best and one of the center for diagnostic study of Human Immunodeficiency Virus that has mutated and resistant from drugs (multiple drug or even extreme drug resistance) in Indonesia, has teached us a lot of things about biosafety and biosecurity.

The lab which located on the eight floor of IASTH building, Salemba 4, Central Jakarta, also focuses on education by accepting undergraduates, master, and even postgraduates students to study inside.