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Team:Hong Kong HKUST/pneumosensor
From 2014.igem.org
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is unaffordable. To provide an affordable solution to combat pneumococcal diseases, we are engineering an <i>E. coli</i> "Pneumosensor", that will | is unaffordable. To provide an affordable solution to combat pneumococcal diseases, we are engineering an <i>E. coli</i> "Pneumosensor", that will | ||
work inside as an in vitro diagnostic device. Through this cheaper and easier diagnosis method, people can prepare themselves better against the | work inside as an in vitro diagnostic device. Through this cheaper and easier diagnosis method, people can prepare themselves better against the | ||
| - | transmission and adversity of <i>S. pneumoniae</i>.< | + | transmission and adversity of <i>S. pneumoniae</i>.<br><br> |
| - | < | + | Pneumosensor has a rewired comCDE signal transduction pathway native to <i>S. pneumoniae</i> that detects |
autoinducer molecules released specifically by <i>S. pneumoniae</i>. It is also equipped with a new promoter for the specific and tight regulation of | autoinducer molecules released specifically by <i>S. pneumoniae</i>. It is also equipped with a new promoter for the specific and tight regulation of | ||
target gene expression in <i>E. coli</i>. </p> | target gene expression in <i>E. coli</i>. </p> | ||
Revision as of 11:17, 13 October 2014
Pneumosensor Project Abstract
Figure 1. Pneumosensor Overview Diagram |
Streptococcus pneumoniae is responsible for approximately 1.6 million deaths every year mostly in developing countries where vaccination
is unaffordable. To provide an affordable solution to combat pneumococcal diseases, we are engineering an E. coli "Pneumosensor", that will
work inside as an in vitro diagnostic device. Through this cheaper and easier diagnosis method, people can prepare themselves better against the
transmission and adversity of S. pneumoniae. |
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