Team:UI-Indonesia/Human Practice/SynBio Shout Out

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<h2>Imagination comes without the restriction of time</h2>
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<p>Jules Verne (1828-1905) is a famous French writer, poet, and playright. He is very famous for his "ahead-of-time" books or commonly known as "science-fiction" books.
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A few books worthy to be mentioned are "Around the World in Eighty Days" and "Twenty Thousand Leagues Under the Sea."
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<h2>In the book he wrote</h2>
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<h2>About Our Project</h2>
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<img width="110" height="147" data-file-width="800" align="left" style="margin-right:20px;margin-bottom:20px" src="https://static.igem.org/mediawiki/2014/b/bc/Ui-indonesia_image_hp_robur.jpg"></img>
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<p>Biofilm is a matrix extracellular polymeric substances (EPS) that is surrounding microbial collonies. It causes more than 65% of all microbial infections. Most of pathogenic bacteria could make biofilm that can cause antibiotic resistance issue and increase its pathogenecity. Our <i>Escherichia coli</i> can degrade biofilm from various bacteria after it seeks them by detecting their quorum sensing molecule. Our team will focus in <i>Vibrio cholerae</i> because it is a cause of cholera as a deadly tropical countries disease. We present our <i>E. coli</i> agent that can degrade biofilm of <i>V. cholerae</i> after it can detect quorum sensing molecule from <i>V. cholerae</i>, CAI-1, by CqsS receptor. Then our <i>E. coli</i> agent will activate motility gene, CheZ, to hunt <i>V. cholerae</i>. When it arrives, our bacteria will degrade the biofilm by secreting enzymes, such as α-amylase, nuclease, and substilisin to break down the matrix and peptide 1018 that will kill <i>V. cholerae</i>.
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<p>In one of his book, Robur the Conqueror, he mentioned an imaginative flying machine ahead of his time.
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</p>
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<h2>And soon to be realized</h2>
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<img align="left" style="margin-right:20px;margin-bottom:20px" src="https://static.igem.org/mediawiki/2014/thumb/e/ef/Ui-indonesia_image_hp_glider.jpg/120px-Ui-indonesia_image_hp_glider.jpg"></img>
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<p>Wright Brother developed the "flying machine" which soon evolved into the first practical fixed-wing aircraft.</p>
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<h2>Hence our team are wondering</h2>
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<p>What we could achieve, if we are free to realize our imagination?
<br>
<br>
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<br>What will you make, if you could engineer a bacteria to do anything?
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<br>
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Our project can be applied in broad spectrum bacteria. Not only <i>Vibrio cholerae</i> but also other bacteria such as: <i>Pseudomonas aerugoinosa</i>, <i>Bacillus substillis</i>, <i>Klebsiella pneumonia</i>, <i>Staphylococcus aureus</i>, and <i>E. coli</i> Top 10.</p>
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<br> In example of making a love perfume from bacteria or even a bacteria that could sing! As we mentioned before, do not afraid to imagine something, flying was an imagination; but now, people flies.
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<h2>And these are what we do!</h2>
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<img width="70%"  align="center" src="https://static.igem.org/mediawiki/2014/e/ec/Ui-indonesia_image_hp_brosur.jpg">
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<h2>So, these are a few of the replies we received...</h2>
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<p>“My imagination is to take a gene from chameleon that encodes color changing trait and put it in a bacteria. I hope that, as this trait is used by chameleon to  detect nearby predator, I want my bacteria adhered in my wall or the trees near my house so  I know if some predators visiting my house.”
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<div align="right">- Ali</div>
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<br>“My bacteria-want-to-make list: a fast wound healing bacteria, a memory enhancer bacteria, and a bacteria that can substitute a lamp and creates a never-die-lamp."
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<div align="right">- Nurul</div>
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<br>“Nothing more interesting than making a bacteria that can distinguish bad and good people. So, all corruptors die in a mass bacterial injection.”
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<div align="right">- Saiful</div>
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<br>“I want to create bacteria that can show our nerve impulse, and determine people thought/mind.”
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<div align="right">- Nia</div>
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<br>“Stain removal bacteria”. I have some spotted clothes which were not able to remove stain by detergents.I want bacteria which degrade pigments and remove stains from clothes."
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<div align="right">- M.N</div>
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</p>
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<h2>And a question directed back to us (?)</h2>
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<p>“Is there any bacteria that can make us invisible?”
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<div align="right">- Jali</div>
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</p>
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<h2>Or even a very cute answer!</h2>
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<p>“Bacteria with hands and legs. It’s enough.”
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<div align="right">- Vina</div>
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</p>
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<h2>CONCLUSION</h2>
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<p>Together, we have seen the wishes and hope, the imagination of the "next generation" of scientists. Well, we could not stop our anxiety on how they will start to move toward, realizing their dreams, in the future.</p>
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Latest revision as of 03:56, 18 October 2014

Imagination comes without the restriction of time

Jules Verne (1828-1905) is a famous French writer, poet, and playright. He is very famous for his "ahead-of-time" books or commonly known as "science-fiction" books.

A few books worthy to be mentioned are "Around the World in Eighty Days" and "Twenty Thousand Leagues Under the Sea."

In the book he wrote

In one of his book, Robur the Conqueror, he mentioned an imaginative flying machine ahead of his time.

And soon to be realized

Wright Brother developed the "flying machine" which soon evolved into the first practical fixed-wing aircraft.

Hence our team are wondering

What we could achieve, if we are free to realize our imagination?

What will you make, if you could engineer a bacteria to do anything?

In example of making a love perfume from bacteria or even a bacteria that could sing! As we mentioned before, do not afraid to imagine something, flying was an imagination; but now, people flies.

And these are what we do!

So, these are a few of the replies we received...

“My imagination is to take a gene from chameleon that encodes color changing trait and put it in a bacteria. I hope that, as this trait is used by chameleon to detect nearby predator, I want my bacteria adhered in my wall or the trees near my house so I know if some predators visiting my house.”

- Ali

“My bacteria-want-to-make list: a fast wound healing bacteria, a memory enhancer bacteria, and a bacteria that can substitute a lamp and creates a never-die-lamp."
- Nurul

“Nothing more interesting than making a bacteria that can distinguish bad and good people. So, all corruptors die in a mass bacterial injection.”
- Saiful

“I want to create bacteria that can show our nerve impulse, and determine people thought/mind.”
- Nia

“Stain removal bacteria”. I have some spotted clothes which were not able to remove stain by detergents.I want bacteria which degrade pigments and remove stains from clothes."
- M.N

And a question directed back to us (?)

“Is there any bacteria that can make us invisible?”

- Jali

Or even a very cute answer!

“Bacteria with hands and legs. It’s enough.”

- Vina

CONCLUSION

Together, we have seen the wishes and hope, the imagination of the "next generation" of scientists. Well, we could not stop our anxiety on how they will start to move toward, realizing their dreams, in the future.