Team:Hong Kong HKUST/pneumosensor
From 2014.igem.org
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<h6><b>Figure 1. Pneumosensor Overview Diagram</h6></b><br> | <h6><b>Figure 1. Pneumosensor Overview Diagram</h6></b><br> | ||
<h7> Quorem-sensing peptide CSP produced by <i>S. pneumoniae</i> is detected by the Detection Module; the response regulator ComE links the Detection Module to the σ<sup>x</sup> Promoters Module which ultimately drives the expression of GFP. </h7> | <h7> Quorem-sensing peptide CSP produced by <i>S. pneumoniae</i> is detected by the Detection Module; the response regulator ComE links the Detection Module to the σ<sup>x</sup> Promoters Module which ultimately drives the expression of GFP. </h7> | ||
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Latest revision as of 19:39, 17 October 2014
Project Pneumosensor Abstract
Figure 1. Pneumosensor Overview Diagram |
Streptococcus pneumoniae is responsible for approximately 1.6 million deaths every year mostly in developing countries where vaccination
is unaffordable (World Health Organization, 2014). Current methods used for diagnosis of pneumococcal diseases include X-ray imaging of chest, PCR assay using blood and Gram stain using sputum (Muench, D. F., 2014). They require sophisticated equipments, help from physicians or laboratory settings, all of which are limited to people in third world countries. To provide an affordable solution to combat pneumococcal diseases, we are engineering an E. coli "Pneumosensor", that will
work inside as an in vitro diagnostic device. Such a device should provide diagnosis result in absence of laboratories, medical equipments or doctors, making it more accessible for the people. Through this cheaper and easier diagnosis method, people can prepare themselves better against the
transmission and adversity of S. pneumoniae. |
References
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