Team:Edinburgh

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<table align="center" style="border-spacing: 5px;"><tr><td><a href="https://2014.igem.org/"><img src="https://static.igem.org/mediawiki/2014/archive/3/3f/20140702191450%21Igem.png" width="50px" height="45px"></a></td><td id="navlink"><a href="https://2014.igem.org/Team:Edinburgh">Home</a></td><td id="navlink"><a href="https://2014.igem.org/Team:Edinburgh/team/">Team</a></td><td id="navlink"><a href="https://igem.org/Team.cgi?id=1399">Profile</a></td><td id="navlink"><a href="https://2014.igem.org/Team:Edinburgh/logic/">Background</a></td><td id="navlink"><a href="https://2014.igem.org/Team:Edinburgh/project/">Project</a></td><td id="navlink"><a href="https://2014.igem.org/Team:Edinburgh/HP/">Policy and Practices</a></td><td id="navlink"><a href="https://2014.igem.org/Team:Edinburgh/modelling/">Modelling</td><td id="navlink"><a href="https://2014.igem.org/Team:Edinburgh/log">Daily log</a></td></table></div>
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<div id="criteria"><a href="https://2014.igem.org/Team:Edinburgh/medal">Medal criteria</a></div>
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<div id="tourright"><a href="https://2014.igem.org/Team:Edinburgh/team/">Start the tour!</a></div>
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   <a href="https://2014.igem.org/Team:Edinburgh"><img id="logo" src="https://static.igem.org/mediawiki/2014/8/8e/Ed14_logo.png" width="200" height="200"></a>
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   <h1>RewirED</h1>
   <h1>RewirED</h1>
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   <p>Smart bacteria could be the computers of the future – but first we have to wire them together. This year Edinburgh is excited to introduce metabolic wiring to iGEM, a novel way for connecting logic gates in different bacterial strains.</p>
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   <p>Better control of bacterial populations should allow more complex biological systems to be created. RewirED has worked to bring the first components of that future closer through iGEM, in order to allow greater access and sharing of scientific knowledge, and greater communication and responsiveness from bacteria.</p>
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<a href="https://2014.igem.org/Team:Edinburgh/logic/">
<a href="https://2014.igem.org/Team:Edinburgh/logic/">
<h2>Our aims</h2>
<h2>Our aims</h2>
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<p>In order to improve globally equality, both monetary and medically, the accessibility of new technologies is imperative. Our project designed a intercellular communication and control system that could be used to stabilise the composition of dynamic population of bacteria. This would simplify the use of complicated biological systems such as microbial consortia.</p>
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<h2>Our Project</h2>
<h2>Our Project</h2>
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<p>Metabolic wires are a new way of connecting logic gates in different cells – their orthogonality and extensibility means there is potentially no limit to how intelligent a population of bacteria can be.</p>
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<p>We focused on the definition of microbial consortia, namely, systems. This was done through three sub-projects; Metabolic wiring and the three wires we investigated, degron characterization to improve the responsiveness of systems, and population control to experiment with actual control mechanisms. Policy and Practices informed the considerations of our model system’s design and it in turn influenced the exploration of these same themes in iGEM teams.</p>
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<p>We set out to make three sets of metabolic wires, using trans-genic aromatic enzymes, cis-genic aromatic genes, and ‘sugar logic.’ We also set out to build a population regulation system to showcase these wires, and a new set of degrons to make the system more robust.</p>
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<h2>Our Sponsors</h2>
<h2>Our Sponsors</h2>
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<a href="2014.igem.org/Team:Edinburgh/acknowledgements"><table>
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Latest revision as of 03:43, 18 October 2014

Modelling

Why do an experiment when a computer can work out the result? Click here to learn about the models we used, the programs we created, and our collaboration with UCL.

 Human Practices

What can our smart bacterial friends tell us about the way human teams work? Are iGEM teams any smarter than a population of smart bacteria?

 Art and Outreach

Learn about some novel ways in which we tried to get the message out about our project.

Our Sponsors

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