Team:Oxford

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<h1>Welcome to Oxford University iGEM homepage</h1>
 
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<p>Welcome to the homepage of the Oxford University iGEM team. The team consists of 6 biochemists, 3 engineers, a biologist, a chemist, a lawyer. The team will spend eight weeks in the summer designing a waste disposal kit from biological components to detect and degrade DCM, a toxic solvent routinely used in the lab.
 
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Even before the project has begun, the team has been promoting Oxford's presence in the competition. It is bringing iGEM teams from across the UK and Europe together to encourage the exchange of ideas and working with the University's Synthetic Biology Society to ensure a legacy beyond the 2014 competition.</p>
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<h1>Recent news</h1>
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<h2>Team planning on attending Sheffield meet up</h2>
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<p>The Oxford iGEM team is planning on attending the meet up organised by the team at the University of Sheffield on Friday the 18th of July. The purpose of this visit will be to continue from the visit that the Oxford team ran.</p>
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<h2>Team members give talk at Royal Society</h2>
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University of Oxford’s first iGEM team presents: DCMation, a novel bioremediation approach whose applications are limited only by the versatility of bacterial metabolism. OxiGEM are tackling environmental pollution by developing a user-friendly device for the detection & degradation of the hazardous yet indispensable solvent dichloromethane (DCM), to illustrate.
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Inspired by the DCM degradation pathway of <font style="font-style: italic;">M. extorquens</font> DM4, our project is driven and refined by the dialogue between modelling simulations and experimental data. Bioremediation is optimised by expressing the DCM degrading system in host strains, along with microcompartments to accelerate the reaction and minimise toxic intermediates. Our biosensor is tuned to our characterisation and improvements of the catalytic efficiency of the system, while incorporation of the bacteria into novel diffusion-limiting biopolymeric beads ensures safe and rapid degradation.
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This all-round modular design and scalability make DCMation ideal for extension to the disposal of many harmful substances. Explore our wiki for more!
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Latest revision as of 19:15, 2 June 2015