Team:LMU-Munich/Notebook/Timeline
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+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/0/02/LMU14_timeline_world.png" ></div> | ||
+ | <div class="date"><center>21. Oct<br>Heinrich-Wieland-Prize-Symposium</center></div> | ||
+ | <div class="text"><center>poster session at a fancy symposium</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_bacillus.png" ></div> | ||
+ | <div class="date"><center>17. Oct<br>First ''S. penumoniae'' sensing experiment </center></div> | ||
+ | <div class="text"><center>Pxyl-comDE PQS-lux was induced with xylose and CSP and the luminescence was measurred.</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><center><img src="https://2014.igem.org/File:LMU14_timeline_bacillus.png" ></div> | ||
+ | <div class="date"><center>16. Oct<br> ></div> | ||
+ | <div class="text"><center>Peptides indicate adhesion to ''S.pneumoniae''</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>17. Oct <br> Subtilin Modification BioBrick correctly sequenced</center></div> | ||
+ | <div class="text"><center> After struggling for a really long time, the Subtilin Modification BioBrick was correctly sequenced</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://2014.igem.org/File:LMU14_timeline_evaluation.png" ></div> | ||
+ | <div class="date"><center>14. Oct <br> Subtilin Immunity BioBrick works! </center></div> | ||
+ | <div class="text"><center> The Subtilin Immunity BioBrick was evaluated by spot-on-lawn assays</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/8/8b/LMU14_timeline_team.png" ></div> | ||
+ | <div class="date"><center>13. Oct<br>Groningen Collaboration Parts received</center></div> | ||
+ | <div class="text"><center>HALLO DU</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>08. Oct <br> BioBricks SHIPPED</center></div> | ||
+ | <div class="text"><center> Our BioBricks were shipped up to Boston</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>02. Oct<br>BBa_K1351028-BBa_K1351034</center></div> | ||
+ | <div class="text"><center>BBa_K1351028-BBa_K1351034 correctly sequenced and packed for submission</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/0/02/LMU14_timeline_world.png" ></div> | ||
+ | <div class="date"><center>30. Sept<br>iGEM talk at freshman week event</center></div> | ||
+ | <div class="text"><center>HALLO DU</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>29. Sept<br>BBa_K1351024 PcomC</center></div> | ||
+ | <div class="text"><center>QS-dependent promoter PcomC of ''S. pneumoniae'' was cloned succesefully in ''E. coli'' and sequenced!</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>29. Sept<br>BBa_K1351025 PcomAB</center></div> | ||
+ | <div class="text"><center>QS-dependent promoter PcomAB of ''S. pneumoniae'' was cloned succesefully in ''E. coli'' and sequenced!</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>24. Sept<br>Part sequenced</center></div> | ||
+ | <div class="text"><center>Part successfully sequenced: [http://parts.igem.org/wiki/index.php?title=Part:BBa_K1351023|BBa_K1351023]</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><img src="https://2014.igem.org/File:LMU14_timeline_evaluation.png" ></div> | ||
+ | <div class="date"><center>18. Sept <br> First luminescence-assays with synthetic AIP-II done</center></div> | ||
+ | <div class="text"><center>Expression of agrCA seems to work!</center></div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>17. Sept <br> Subtilin Immunity BioBrick correctly sequenced</center></div> | ||
+ | <div class="text"><center> The Subtilin Immunity BioBrick was correctly sequenced</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/8/8b/LMU14_timeline_team.png" ></div> | ||
+ | <div class="date"><center>13. Sept - 14. Sept<br>Aachen Meetup</center></div> | ||
+ | <div class="text"><center>HALLO DU</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>08. Sept <br> pBS2E-PxylA-agrC-IIA constructed</center></div> | ||
+ | <div class="text"><center>pBS2E-PxylA-agrC-IIA correctly sequenced</center></div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/8/8b/LMU14_timeline_team.png" ></div> | ||
+ | <div class="date"><center>03. Sept<br>MegaWikiDay</center></div> | ||
+ | <div class="text"><center>We got together for a whole day to discuss and decide on the Wiki's contents and layout</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>25. Aug - 04. Sept<br>LMU Summer School workshop</center></div> | ||
+ | <div class="text"><center>Robert and Patrick attended the LMU Summer School workshop on "How do innovative products enter the german health care system?" in order to learn more about the regulation of new medical products</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>29. Aug<br>BBa_K1351021</center></div> | ||
+ | <div class="text"><center>Bba_E1010 successfully improved by deleting a AgeI restriction site</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>07. Aug <br>SynBioDay</center></div> | ||
+ | <div class="text"><center>Presentation of our Project and eduactional work about SynBio at the Deutsches Museum</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>29. July<br>NEVA FORGET</center></div> | ||
+ | <div class="text"><center>ComDE mutagenesis to eliminate undesired BioBrick restriction sites started</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center> 24. Jul <br> Subtilin Peptide BioBricks finished </center></div> | ||
+ | <div class="text"><center> BioBricks for SpaS were correctly sequenced! :-) </center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>10. Jul<br>Open Door Day of the Faculty for Biology of the LMU</center></div> | ||
+ | <div class="text"><center>"We presented our project at the [http://www.lsm.bio.lmu.de/news/past-events1/openhouseday2014/index.html Open Doors Day] at the LMU Biology Center</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>09. Jul<br>PANEL DISCUSSION</center></div> | ||
+ | <div class="text"><center>We invited Experts on SynBio to the LMU's BioCentre. Discussion BLABLA</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>02. Jul - 03. Jul<br>Kongress Nuremberg</center></div> | ||
+ | <div class="text"><center>HALLO DU</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>25. Jun<br>iGEM@School</center></div> | ||
+ | <div class="text"><center>The highschool students of the Gymnasium in Neubiberg visited us and had a exciting day at the lab!</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>17. June<br>Succesfull amplification of ''comDE'' of R6 ''S. pneumoniae''</center></div> | ||
+ | <div class="text"><center>Now we can start to transferre the quorums sensing system of ''S. pneumoniae first into ''E. coli'' and then into'' to ''B. subtilis''!</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://2014.igem.org/File:LMU14_timeline_bacillus.png" ></div> | ||
+ | <div class="date"><center>04. June <br> ''S. pneumoniae'' strain arrived! </center></div> | ||
+ | <div class="text"><center> The R6 arrived in our lab today </center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><center><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>26. May<br>THE MEETUP ATTENDS CAS</center></div> | ||
+ | <div class="text"><center>German iGEM Teams attended the Center for Advanced studies</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/8/8b/LMU14_timeline_team.png" ></div> | ||
+ | <div class="date"><center>24. May - 26. May<br>MEETUP OF GERMAN IGEM TEAMS</center></div> | ||
+ | <div class="text"><center>The German iGEM Teams came to Munich, and presented their Projects to each other</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-left biobrick"> | ||
+ | <div class="icon"><center><img src="https://2014.igem.org/File:LMU14_timeline_bacillus.png" ></div> | ||
+ | <div class="date"><center>May<br>LABWORK STARTED</center></div> | ||
+ | <div class="text"><center>We sent our first Labbies to work</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>04. Apr<br>ANALYTICA</center></div> | ||
+ | <div class="text"><center>We visited the Analytica in Munich and approached corporations in search of potential sponsors</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | <div class="bg-color-2 timeline-item-right biobrick"> | ||
+ | <div class="icon"><img src="https://static.igem.org/mediawiki/2014/c/cb/LMU14_timeline_icon_1.png" ></div> | ||
+ | <div class="date"><center>22. Mar - 23. Mar<br>iGEM Weekend</center></div> | ||
+ | <div class="text"><center>All the Team Members met for a whole weekend to plan our project</center></div> | ||
+ | </div> | ||
+ | <br> | ||
+ | |||
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+ | |||
+ | </div> | ||
+ | |||
+ | </div> | ||
+ | </html> | ||
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Latest revision as of 03:59, 18 October 2014
Timeline
Heinrich-Wieland-Prize-Symposium
First ''S. penumoniae'' sensing experiment
>
Subtilin Modification BioBrick correctly sequenced
Subtilin Immunity BioBrick works!
Groningen Collaboration Parts received
BioBricks SHIPPED
BBa_K1351028-BBa_K1351034
iGEM talk at freshman week event
BBa_K1351024 PcomC
BBa_K1351025 PcomAB
Part sequenced
First luminescence-assays with synthetic AIP-II done
Subtilin Immunity BioBrick correctly sequenced
Aachen Meetup
pBS2E-PxylA-agrC-IIA constructed
MegaWikiDay
LMU Summer School workshop
BBa_K1351021
SynBioDay
NEVA FORGET
Subtilin Peptide BioBricks finished
Open Door Day of the Faculty for Biology of the LMU
PANEL DISCUSSION
Kongress Nuremberg
iGEM@School
Succesfull amplification of ''comDE'' of R6 ''S. pneumoniae''
''S. pneumoniae'' strain arrived!
THE MEETUP ATTENDS CAS
MEETUP OF GERMAN IGEM TEAMS
LABWORK STARTED
ANALYTICA
iGEM Weekend
Hi there!
Welcome to our Wiki! I'm BaKillus, the pathogen-hunting microbe, and I'll guide you on this tour through our project. If you want to learn more about a specific step, you can simply close the tour and come back to it anytime you like. So let's start!
What's the problem?
First of all, what am I doing here? The problem is, pathogenic bacteria all around the world are becoming more and more resistant against antimicrobial drugs. One major reason for the trend is the inappropriate use of drugs. With my BaKillus super powers, I want to reduce this misuse and thus do my part to save global health.
Sensing of pathogens
To combat the pathogenic bacteria, I simply eavesdrop on their communication. Bacteria talk with each other via quorum sensing systems, which I use to detect them and trigger my responses.
Adhesion
The more specific and effective I can use my powers, the lower the danger is of provoking new resistance development. So I catch pathogens whenever I get hold of them and stick to them until my work is done.
Killing
Talking about my work - killing pathogens is finally what I am made for. In response to quorum sensing molecules of the pathogens, I export a range of antimicrobial substances leading to dissipation of biofilms and the killing of the targeted bacteria.
Suicide switch
When the job is done and all the bad guys are finished, you don't need a super hero anymore. So after fulfilling my work I say goodbye to the world by activating my suicide switch.
Application
Of course I'm not only a fictional hero, but a very real one. In two different prototypes, I could be used for diagnosis or treatment of pathogen-caused diseases. However, there is still a whole lot of regulational and economical questions that have to be answered before.
See you!
So now you know my short story - and it is time for me to return to my fight for a safer world. Feel free to take a closer look on my super powers, the process of my development or the plans for a medical application.