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<p>Sie sind hier:&nbsp; <a href="index.php?id=23" >wiki</a> &rsaquo;&nbsp;<a href="index.php?id=28" >Project</a> &rsaquo;&nbsp;<span class="current"><a href="index.php?id=40" >Overview</a></span></p>

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<ul class="menu"><li class="first"><a href="index.php?id=160" >Home</a></li><li class="active"><a href="index.php?id=28" >Project</a><ul class="menu2"><li class="active first"><a href="index.php?id=40" >Overview</a></li><li><a href="index.php?id=41" >Anthocyanins</a></li><li><a href="index.php?id=42" >Grätzel cell / DSC</a></li><li><a href="index.php?id=129" >Pathway</a></li><li><a href="index.php?id=128" >Scaffold</a></li><li class="last"><a href="index.php?id=69" >Safety</a></li></ul></li><li><a href="index.php?id=29" >Results</a></li><li><a href="index.php?id=30" >Policy & Practices</a></li><li><a href="index.php?id=31" >Achievements</a></li><li><a href="index.php?id=32" >Notebook</a></li><li><a href="index.php?id=33" >Team</a></li><li class="last"><a href="index.php?id=34" >Gallery</a></li></ul>

<!--TYPO3SEARCH_begin--><div id="c24" class="csc-default"><div class="csc-header csc-header-n1"><h1 class="csc-firstHeader">Overview</h1></div><div class="csc-textpic csc-textpic-left csc-textpic-above"><div class="csc-textpic-imagewrap" data-csc-images="1" data-csc-cols="2"><figure class="csc-textpic-image csc-textpic-last"><img src="https://static.igem.org/mediawiki/parts/9/9d/Flowchart.png" width="600" height="451" alt=""><figcaption class="csc-textpic-caption">Figure 1: Flowchart of our project</figcaption></figure></div><div class="csc-textpic-text"><p><span lang="EN-US">Access to electricity is especially in rural areas in Africa a major issue. Even a few additional hours of electrical power and lighting have massive positive effects on commerce, health, education and household net income. Two of the eight <a href="http://www.un.org/millenniumgoals/" title="Opens external link in new window" target="_blank" class="external-link-new-window">UN millennium goals</a> (eradicating extreme poverty and hunger, achieving universal primary education) are therefore directly linked to the electrification of poor regions and many other millennium goals can be reached indirectly.</span>

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<p><span lang="EN-US">Our off-the-grid approach will contribute to the fight against poverty by producing electricity with <a href="index.php?id=42" title="Opens internal link in current window" class="internal-link">dye-sensitized solar cells</a> (DSC or Grätzel cells) and bringing cheap renewable energy to rural areas.</span>

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<p><span lang="EN-US">We produced the main component of our Grätzel cell, the red dye <a href="index.php?id=41" title="Opens internal link in current window" class="internal-link">pelagornidin</a>, efficiently in <i>E. coli </i>by applying different means of metabolic engineering. We provided the iGEM registry with an improved version of a <a href="index.php?id=128" title="Opens internal link in current window" class="internal-link">protein scaffold</a> so every team can easily improve their metabolic channeling of their own biosynthetic pathway. Furthermore we <a href="index.php?id=45" title="Opens internal link in current window" class="internal-link">modelled</a> and cloned a mutated version of the anthocyanidin synthase, a central enzyme for flavonoid production, to have a more accessible substrate pocket.</span>

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<p><span lang="EN-US">During the course of our project we developed several open hardware devices for our Grätzel cells and a cheap agarose gel chamber. We made the 3D-printer files and detailed instructions for the construction of our devices publicly available on our Wiki.</span>

<p><span lang="EN-US">Last, but not least we collaborated with the <a href="index.php?id=47" title="Opens internal link in current window" class="internal-link">Synenergene</a> project to take our Policy &amp; Practices project to the next level. We developed an <a href="index.php?id=48" title="Opens internal link in current window" class="internal-link">application scenario</a> as realistic as possible and examined possible unwanted effects of our project in a <a href="index.php?id=49" title="Opens internal link in current window" class="internal-link">techno-morale vignette</a>. Based on our findings we even adopted our biosynthetic pathway.</span></p></div></div></div><div id="c217" class="csc-default"><div class="csc-textpic csc-textpic-left csc-textpic-above"><div class="csc-textpic-imagewrap" data-csc-images="1" data-csc-cols="2"><figure class="csc-textpic-image csc-textpic-last"><img src="https://static.igem.org/mediawiki/parts/c/cb/Blume_runterskaliert.png" width="600" height="401" alt=""><figcaption class="csc-textpic-caption">Figure 2: Plants produce anthocyanins</figcaption></figure></div></div></div><!--TYPO3SEARCH_end-->