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Team:CityU HK
From 2014.igem.org
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<html> | <html> | ||
<html lang="en"> | <html lang="en"> | ||
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| + | <link href='http://fonts.googleapis.com/css?family=Poiret+One' rel='stylesheet' type='text/css'> | ||
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| + | <style> | ||
| + | /*.carousel-inner { | ||
| + | -webkit-box-shadow: 0 8px 6px -6px black; | ||
| + | -moz-box-shadow: 0 8px 6px -6px black; | ||
| + | box-shadow: 0 8px 6px -6px black;*/ | ||
| + | } | ||
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| + | .carousel-inner .carousel-caption { | ||
| + | padding-top: 100px; | ||
| + | padding-bottom: 100px; | ||
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| + | } | ||
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| + | .btn-custom { | ||
| + | padding: 9px 30px 9px 30px; | ||
| + | font-family: 'Quattrocento Sans', sans-serif; | ||
| + | font-size: 20px; | ||
| + | border-bottom: 4px solid #36ae88; | ||
| + | color: #fff; | ||
| + | background: #4eecba; | ||
| + | font-weight: bold; | ||
| + | margin: 0 20px 40px 20px; | ||
| + | } | ||
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| + | .btn-custom:hover { | ||
| + | color: #fff; | ||
| + | background-color: orange; | ||
| + | border-bottom: 4px solid #EC8318; | ||
| + | } | ||
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| + | .btn-custom:visited { | ||
| + | color: #fff; | ||
| + | background-color: orange; | ||
| + | border-bottom: 4px solid #EC8318; | ||
| + | } | ||
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| + | #feature-icon img { | ||
| + | max-width: 100%; | ||
| + | max-height: 100%; | ||
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| + | #abstract { | ||
| + | background: #F0EEEA; | ||
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| + | #abstract h2{ | ||
| + | color: #676767; | ||
| + | text-align: center; | ||
| + | margin-bottom: 40px; | ||
| + | font-size: 4em; | ||
| + | font-family: "brandon-grotesque", sans-serif; | ||
| + | font-weight: 700; | ||
| + | text-shadow: 0px 2px 0px rgba(0, 0, 0, 0.2); | ||
| + | padding-top: 100px; | ||
| + | margin-top: 0px; | ||
| + | letter-spacing: 8px; | ||
| + | } | ||
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| + | #abstract p { | ||
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| + | font-family: 'Raleway', sans-serif; | ||
| + | line-height: 2em; | ||
| + | text-align: center; | ||
| + | padding-left: 200px; | ||
| + | padding-right:200px; | ||
| + | padding-top: 10px; | ||
| + | padding-bottom: 100px; | ||
| + | font-size: 18px; | ||
| + | color: #444; | ||
| + | } | ||
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| + | </style> | ||
<body> | <body> | ||
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<li data-target="#carousel-example-generic" data-slide-to="1"></li> | <li data-target="#carousel-example-generic" data-slide-to="1"></li> | ||
<li data-target="#carousel-example-generic" data-slide-to="2"></li> | <li data-target="#carousel-example-generic" data-slide-to="2"></li> | ||
| + | <li data-target="#carousel-example-generic" data-slide-to="3"></li> | ||
</ol> | </ol> | ||
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<div class="carousel-inner"> | <div class="carousel-inner"> | ||
<div class="item active"> | <div class="item active"> | ||
| - | <img src=" | + | <img src="https://static.igem.org/mediawiki/2014/d/d7/CityU_HK_slide1.png" width=100% / > |
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<div class="carousel-caption"> | <div class="carousel-caption"> | ||
| - | + | <a id="btn-custom" href="#Lower" id="#Lower class="anchorLink"><button class="btn btn-custom">ABSTRACT</button></a> | |
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</div> | </div> | ||
</div> | </div> | ||
<div class="item"> | <div class="item"> | ||
| - | <img src=" | + | <img src="https://static.igem.org/mediawiki/2014/4/4a/CityU_HK_slide2.png" /> |
| + | <div class="carousel-caption"> | ||
| + | <a href="https://2014.igem.org/Team:CityU_HK/project/module_fad"><button class="btn btn-custom">FadD & FadL</button></a> | ||
| + | <a href="https://2014.igem.org/Team:CityU_HK/project/module_tesA"><button class="btn btn-custom">'TesA</button></a> | ||
| + | <a href="https://2014.igem.org/Team:CityU_HK/project/module_desaturase"><button class="btn btn-custom">Desaturase</button></a> | ||
| + | </div> | ||
</div> | </div> | ||
<div class="item"> | <div class="item"> | ||
| - | <img src="https://static.igem.org/mediawiki/2014/ | + | <img src="https://static.igem.org/mediawiki/2014/9/98/CityU_HK_slide3.png"> |
<div class="carousel-caption"> | <div class="carousel-caption"> | ||
| - | < | + | <a href="https://2014.igem.org/Team:CityU_HK/HumanPractice"><button class="btn btn-custom">Learn More</button></a> |
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</div> | </div> | ||
</div> | </div> | ||
| + | <div class="item"> | ||
| + | <img src="https://static.igem.org/mediawiki/2014/f/f6/CityU_HK_hp_group.JPG" width=100% /> | ||
| + | <div class="carousel-caption"> | ||
| + | <a href="https://2014.igem.org/Team:CityU_HK/TeamMember"><button class="btn btn-custom">Meet the Team</button></a> | ||
| + | </div> | ||
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</div> | </div> | ||
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</div> | </div> | ||
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<!--===================== Abstract =========================--> | <!--===================== Abstract =========================--> | ||
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<div class="anchor" id="Lower"></div> | <div class="anchor" id="Lower"></div> | ||
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<div class="col-sm-12 col-md-12"> | <div class="col-sm-12 col-md-12"> | ||
<h2>Abstract</h2> | <h2>Abstract</h2> | ||
| - | <p>Obesity has now reached epidemic proportions worldwide, which has serious consequences because obesity is associated with various chronic human diseases such as diabetes, hypertension and cardiovascular diseases. With the aim to protect oneself against obesity and debilitating diseases caused by a high-fat diet, we are using a synthetic biology approach to design an Escherichia coli strain (called Fit Coli) that has an enhanced ability to uptake and convert excess fatty acids from fatty foods into a-linolenic acid (ALA). The strategy is to engineer the fadL and fadD genes along with three desaturase genes to facilitate the uptake of long-chain fatty acids and their biotransformation to ALA by the “Fit Coli” strain. It is predicted that the ALA converted from excess fatty acids by Fit Coli is converted to docosahexaenoic acid (DHA), an omega-3-fatty acid, in the human gut, which is well known to have many positive health benefits.</p> | + | <p><b>Obesity</b> has now reached epidemic proportions worldwide, which has serious consequences because obesity is associated with various chronic human diseases such as diabetes, hypertension and cardiovascular diseases. With the aim to protect oneself against obesity and debilitating diseases caused by a high-fat diet, we are using a synthetic biology approach to design an <i>Escherichia coli</i> strain (called <b><font color=#3cc>Fit. Coli</font></b>) that has an enhanced ability to uptake and convert excess fatty acids from fatty foods into a-linolenic acid (ALA). The strategy is to engineer the <i>fadL</i> and <i>fadD</i> genes along with three desaturase genes to facilitate the uptake of long-chain fatty acids and their biotransformation to ALA by the “Fit. Coli” strain. It is predicted that the ALA converted from excess fatty acids by Fit. Coli is converted to docosahexaenoic acid (DHA), an omega-3-fatty acid, in the human gut, which is well known to have many positive health benefits.</p> |
</div> | </div> | ||
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<div id="footer" class="row"> | <div id="footer" class="row"> | ||
<div class="col-md-7"> | <div class="col-md-7"> | ||
| - | < | + | <h3>Sponsors</h3> |
| - | + | <a href="http://www.cityu.edu.hk/" target="_blank"><img src="https://static.igem.org/mediawiki/2014/9/9c/CityU_HK_citylogo.png" width="95"></a> | |
| - | + | <a href="http://www6.cityu.edu.hk/bhdbapp/deptweb/index.html" target="_blank"><img src="https://static.igem.org/mediawiki/2014/9/98/CityU_HK_bchlogo.png" width="80"></a> | |
| - | < | + | <img src="https://static.igem.org/mediawiki/2014/b/b1/CityU_HK_Invitrogen.png" width="100"> |
| - | <p>email: <a href=" | + | <img src="https://static.igem.org/mediawiki/2014/7/7a/CityU_HK_Neblogocol.png" width="135"> |
| - | <a href=" | + | <img src="https://static.igem.org/mediawiki/2014/d/dc/CityU_HK_IDT-Logo.png" width="125"> |
| - | <a href=" | + | </div> <!-- end of col-md-7--> |
| - | <a href=" | + | |
| - | + | <div class="col-md-5"> | |
| - | </div> <!-- end of | + | <h3>Stay connected!</h3> |
| + | <p>email: <a href="mailto:cityuhk.igem@gmail.com">cityuhk.igem@gmail.com</a></p> | ||
| + | <a href="http://www.facebook.com/igem.2014CityU"><img src="https://static.igem.org/mediawiki/2014/3/31/CityU_HK_fb_logo.png" width="50" height="48"></a> | ||
| + | <a href="http://twitter.com/CityUHK_iGEM"><img src="http://ibo2014.org/wordpress/wp-content/themes/ibo2014/img/navbar/twitter_icon.png" width="49" height="51"></a> | ||
| + | <a href="http://www.youtube.com/channel/UC0_bUWwafB4m0K6mFdXN7-w"><img src="https://static.igem.org/mediawiki/2014/1/12/CityU_HK_youtube_logo.png" width="52" height="50"></a> | ||
| + | </div> <!--end of col-md-5--> | ||
| + | </div> <!-- end of row--> | ||
| + | |||
| + | <div class="row"> | ||
| + | <div id="copyright" class="col-md-12"> | ||
| + | <p>Copyright © iGEM CityU HK 2014. All Rights Reserved</p> | ||
| + | </div> | ||
| + | </div> | ||
| + | <!--end of footer--> | ||
</body> | </body> | ||
</html> | </html> | ||
Latest revision as of 00:22, 18 October 2014
Abstract
Obesity has now reached epidemic proportions worldwide, which has serious consequences because obesity is associated with various chronic human diseases such as diabetes, hypertension and cardiovascular diseases. With the aim to protect oneself against obesity and debilitating diseases caused by a high-fat diet, we are using a synthetic biology approach to design an Escherichia coli strain (called Fit. Coli) that has an enhanced ability to uptake and convert excess fatty acids from fatty foods into a-linolenic acid (ALA). The strategy is to engineer the fadL and fadD genes along with three desaturase genes to facilitate the uptake of long-chain fatty acids and their biotransformation to ALA by the “Fit. Coli” strain. It is predicted that the ALA converted from excess fatty acids by Fit. Coli is converted to docosahexaenoic acid (DHA), an omega-3-fatty acid, in the human gut, which is well known to have many positive health benefits.
Sponsors
Copyright © iGEM CityU HK 2014. All Rights Reserved
