Team:ITESM-Guadalajara

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   <meta name="description" content="Team ITESM - Guadalajara Wiki for the iGEM competition of 2014">
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   <meta name="author" content="Gerardo Martín del Campo">
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   <meta name="author" content="Irving Fernando Alvarez Vazquez, Oswaldo Avalos">
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    <h1><b1><font size=20>Bio San</font></b></h1>
 
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<div class="row center-block"><div class="col-md-3 col-md-offset-3"><img src="https://static.igem.org/mediawiki/2014/4/45/BioPhrame_logo.png"></div> <div class="col-md-3"><h1 class="text-success">iGEM Wiki</h1></div>
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    Chitosan is a polysaccharide found in abundance in shrimp shell. The current extraction methods involve the use of strong acids and alkalis, these substances are dangerous wastes that can compromise the integrity of soil and water where they are disposed.
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    <br><br>Due to its stability and biocompatibility, chitosan has been widely used in pharmaceutical, food, and cosmetic industries, among many others. The Chitosan global market has an estimated value of $20 billion USD. Particularly, the pharmaceutical industry represents on average 1.2% of total GDP in Mexico and has grown at a 10% rate since 2008.
 
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    <br><br>Therefore, it is imperative to develop a new and efficient extraction process, that is also eco-friendly. We’ve developed a new process that consists in the pretreatment of shrimp shells, followed by a fermentation in which it is demineralized and deproteinized by B. subtilis. Finally, it goes through a deacetylation process in a fermentation performed by our genetically modified E. coli strain. This modified bacterium contains 6 different enzymes that are found naturally in microorganisms that are capable of cutting and deacetylating chitin for the generation of chitosan. The action of these enzymes and a careful temperature treatment will allow us to generate chitosan with a 90% deacetylation degree. This deacetylation degree is the required one by the pharmaceutical industry, our target market.
 
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    Team Profile section
 
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Biophrame Technologies focuses in innovating, developing and improving technologies based on synthetic biology to create optimized and sustainable industrial processes which can guarantee quality products for our customers.</p>
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    Parts section
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We believe the biotechnology we develop can help us not only to optimize time and resources, but to take care of the environment and improve the lives in our community, both regional and global. That is why raw material used in our processes is waste from other industrial process of other companies.</p>
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<video width="100%" height="500px" controls> <source type="video/mp4" src="https://static.igem.org/mediawiki/2014/b/b7/BIOPHRAMEGDLpitch.mp4"></video>
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    Modeling section
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    Notebook section
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<h2>OUR PRODUCT</h2>
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<center><img src="https://static.igem.org/mediawiki/2014/4/44/BIOPHRAMEbiokProducts.jpg" width="50%"></center>
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Our main product is 'BioK' chitosan. Chitosan is a natural fiber product with multiple applications in pharmaceuticals, agrochemicals, water treatment, textile finishing, food, cosmetics, pulp and paper, photography and tissue engineering. BioK is the result of a biological production process based on genetically modified organisms which is productive, cost effective and waste reductive. In our process, chitin extracted from shrimp shells waste undergoes a process of demineralization, deproteinization and deacetilatyion by the action of two bacteria. The behavior of these bacteria is controlled by induced temperature changes, guaranteeing no chemical use in the process.</p>
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<video width="100%" height="500px" controls> <source type="video/mp4" src="https://static.igem.org/mediawiki/2014/f/f2/BIOPHRAMEGDLchitosanProcess.mp4"></video>
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We are strategically located in Guadalajara, the second most populated city in Mexico and responsible of 7% of national gross domestic product. Our goal in the long term is to fulfil the Mexican demand of medium and high purity chitosan and to become the first Mexican exporter of high purity chitosan. We want to create dream jobs for young Mexican engineers and export our biotechnology worldwide.</p>
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</div></br>
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<div class="col-md-2 col-md-offset-3"><a href="http://www.itesm.mx/wps/wcm/connect/Campus/GDA/Guadalajara/" ><img src="https://static.igem.org/mediawiki/2014/9/93/BIOPHRAMEGDLLogo_tecnologicoDeMonterrey-300x168.jpg"  data-toggle="tooltip"  title="ITESM Guadalajara"></a></div>
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<div class="col-md-2"><a href="http://sergionc.com/web/"><img src="https://static.igem.org/mediawiki/2014/3/33/BIOPHRAMEGDLLogo_sergionc-300x168.jpg" data-toggle="tooltip"  title="Sergionc Video Mapping"></a></div>
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<?php
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<div class="col-md-12 faceBot"></br><div class="col-md-2 col-md-offset-3"><img src="https://static.igem.org/mediawiki/2014/e/ef/Biophrame_logo_footer_500x150.png" class="img-responsive"><small style="color:white">Biophrame Technologies is a biotech company and manufacturer specialized in the production of Chitosan.</small></div>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:ITESM-Guadalajara&action=edit"style="color:#190718"> Click here  to edit this page!</a> </p>
 
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Latest revision as of 03:21, 18 October 2014

iGEM Wiki

Biophrame Technologies focuses in innovating, developing and improving technologies based on synthetic biology to create optimized and sustainable industrial processes which can guarantee quality products for our customers.

We believe the biotechnology we develop can help us not only to optimize time and resources, but to take care of the environment and improve the lives in our community, both regional and global. That is why raw material used in our processes is waste from other industrial process of other companies.

OUR PRODUCT

Our main product is 'BioK' chitosan. Chitosan is a natural fiber product with multiple applications in pharmaceuticals, agrochemicals, water treatment, textile finishing, food, cosmetics, pulp and paper, photography and tissue engineering. BioK is the result of a biological production process based on genetically modified organisms which is productive, cost effective and waste reductive. In our process, chitin extracted from shrimp shells waste undergoes a process of demineralization, deproteinization and deacetilatyion by the action of two bacteria. The behavior of these bacteria is controlled by induced temperature changes, guaranteeing no chemical use in the process.

We are strategically located in Guadalajara, the second most populated city in Mexico and responsible of 7% of national gross domestic product. Our goal in the long term is to fulfil the Mexican demand of medium and high purity chitosan and to become the first Mexican exporter of high purity chitosan. We want to create dream jobs for young Mexican engineers and export our biotechnology worldwide.



Biophrame Technologies is a biotech company and manufacturer specialized in the production of Chitosan.

Retrieved from "http://2014.igem.org/Team:ITESM-Guadalajara"