|
|
| Line 8: |
Line 8: |
| | | | |
| | | | |
| - | <br>
| |
| - | Cockroach is one of the pests we often see in our house. Usually, we use a pesticide to kill them. However, commercially available pesticides contain harmful chemical compounds for environment and even for human. Therefore, we will produce safe and harmless chemical compounds to kill cockroach using E. coli.
| |
| - | <br>
| |
| - | In our projects, we produce 3,3 diketotrehalose, which is a trehalase inhibitor. Cockroaches produce energy to live from trehalose by producing glucose from trehalose. To produce glucose form trehalose, cockroaches utilize an enzyme named trehalase. Therefore, inhibition of trehalase activity will result in death of cockroaches.
| |
| - | <br>
| |
| - | Our E. coli producing trehalase inhibitor will kill cockroaches without doing harm environment or human!
| |
| | | | |
| - | <br>
| |
| | <br> | | <br> |
| | | | |
| Line 76: |
Line 69: |
| | <tr> <td colspan="3" height="5px"> </td></tr> | | <tr> <td colspan="3" height="5px"> </td></tr> |
| | | | |
| - |
| |
| - | <!--requirements section -->
| |
| - | <tr><td colspan="3"> <h3> Requirements </h3></td></tr>
| |
| | <tr> | | <tr> |
| - | <td width="45%" valign="top"> | + | <td><h1>Project Discription</h1></td> |
| - | | + | </tr> |
| - | <p> Please be sure to keep these links, your audience will want to find your: </p> | + | <tr> |
| - | | + | <td> |
| - | <!-- Links to other team pages --> | + | <br> |
| - | <ul>
| + | <h2><strong><i>Exterminator coli</i></strong>: an engineered <i>E. coli</i> to safely eradicate roaches </h2><br> |
| - | <li><a href="https://2014.igem.org/Team:Tokyo-NoKoGen">Home</a> </li>
| + | <p>Many pesticides use neurotoxins that show toxicity not only to insects but also towards other species, including mammals. We therefore set out to construct an <i>E. coli</i> that can safely eradicate cockroaches but not affect mammals.</p> |
| - | <li><a href="https://2014.igem.org/Team:Tokyo-NoKoGen/Team">Team</a> </li>
| + | <p>Cockroaches and many other insects store their energy in the form of trehalose and use the enzyme trehalase to convert it to glucose when needed. Our engineered <i>E. coli</i> will overexpress the enzymes OtsA and OtsB to produce trehalose, and glucose-3-dehydrogenase to convert trehalose to 3,3’-diketotrehalose, an inhibitor of trehalase that is not toxic for mammals. Our engineered <i>Exterminator coli</i> will help eradicate roaches from homes without harming humans or pets.</p> |
| - | <li><a href="https://igem.org/Team.cgi?year=2013&team_name=Tokyo-NoKoGen">Official Team Profile</a> </li> | + | |
| - | <li><a href="https://2014.igem.org/Team:Tokyo-NoKoGen/Project">Project</a> </li> | + | |
| - | <li><a href="https://2014.igem.org/Team:Tokyo-NoKoGen/Parts">Parts</a> </li> | + | |
| - | <li><a href="https://2014.igem.org/Team:Tokyo-NoKoGen/Modeling">Modeling</a> </li> | + | |
| - | <li><a href="https://2014.igem.org/Team:Tokyo-NoKoGen/Notebook">Notebook</a> </li> | + | |
| - | <li><a href="https://2014.igem.org/Team:Tokyo-NoKoGen/Safety">Safety</a> </li>
| + | |
| - | <li><a href="https://2014.igem.org/Team:Tokyo-NoKoGen/Attributions">Attributions</a> </li>
| + | |
| - | | + | |
| - | </ul> | + | |
| - | | + | |
| - | </td>
| + | |
| - | | + | |
| - | <td > </td>
| + | |
| - | <td width="45%">
| + | |
| - | | + | |
| - | <p>There are a few wiki requirements teams must follow:</p> | + | |
| - | <ul>
| + | |
| - | <li>All pages, images and files must be hosted on the <a href ="https://2014.igem.org/Special:Upload"> 2014.igem.org server</a>. </li>
| + | |
| - | <li>All pages must be created under the team’s name space.</li> | + | |
| - | <li>As part of your documentation, keep the links from the menu to the left. </li>
| + | |
| - | <li>Do not use flash in wiki code. </li>
| + | |
| - | <li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
| + | |
| - | </ul>
| + | |
| - | <p>Visit the <a href="https://2014.igem.org/Wiki_How-To"> Wiki How To page </a> for a complete list of requirements, tips and other useful information. </p>
| + | |
| | | | |
| | + | <br> |
| | </td> | | </td> |
| | </tr> | | </tr> |
| | | | |
| | | | |
| - | <tr> <td colspan="3" height="15px"> </td></tr>
| |
| - | <tr><td bgColor="#e7e7e7" colspan="3" height="1"> </tr>
| |
| | | | |
| | | | |
| - | <!--tips -->
| |
| - | <tr><td colspan="3" > <h3> Tips </h3></td></tr>
| |
| - |
| |
| - | <tr>
| |
| - | <td width="45%" valign="top">
| |
| - | <p>We are currently working on providing teams with some easy to use design templates.
| |
| - | <br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
| |
| - |
| |
| - | <ul>
| |
| - | <li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
| |
| - | <li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
| |
| - | <li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
| |
| - | <li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
| |
| - | <li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
| |
| - | </ul>
| |
| - |
| |
| - | <p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a> lists. </p>
| |
| - | </td>
| |
| - |
| |
| - | <td> </td>
| |
| - | <td width="45%">
| |
| - |
| |
| - | <p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
| |
| - |
| |
| - | <ul>
| |
| - | <li>State your accomplishments! Tell people what you have achieved from the start. </li>
| |
| - | <li>Be clear about what you are doing and what you plan to do.</li>
| |
| - | <li>You have a global audience! Consider the different backgrounds that your users come from.</li>
| |
| - | <li>Make sure information is easy to find; nothing should be more than 3 clicks away. </li>
| |
| - | <li>Avoid using very small fonts and low contrast colors; information should be easy to read. </li>
| |
| - | <li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="">iGEM 2013 calendar</a> </li>
| |
| - | <li>Have lots of fun! </li>
| |
| - | </ul>
| |
| - | </br>
| |
| - | </td>
| |
| | </tr> | | </tr> |
| | </table> | | </table> |
"
