Team:UI-Indonesia

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{{:Team:UI-Indonesia/Templates/Header}}
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<!-- Scripts --> <!--- Thank you to TU-Munich 2013 IGEM Team!! :) -->
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<script src="https://2013.igem.org/Team:TU-Munich/TUM13_jquery-1.10.2.js?action=raw&ctype=text/javascript" type="text/javascript"></script>
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<script src="https://2013.igem.org/Team:TU-Munich/TUM13_bxslider.js?action=raw&ctype=text/javascript" type="text/javascript"></script>
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<script src="https://2014.igem.org/Team:UI-Indonesia/script?action=raw&ctype=text/javascript" type="text/javascript"></script>
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<link href="https://2014.igem.org/Team:UI-Indonesia/bxslider.css?action=raw&ctype=text/css" type="text/css" rel="stylesheet">
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<style>
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#top-section { /*-- styling for default menu bar (edit, page, history, etc.) --*/
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<link rel="stylesheet" href="https://2014.igem.org/Team:UI-Indonesia/css/main?action=raw&ctype=text/css" type="text/css" />
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<body>
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<ul class="bxslider">
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<li><img src="https://static.igem.org/mediawiki/2014/a/af/UI-Indonesia_Image_MI-Header.png" /></li>
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<li><img src="https://static.igem.org/mediawiki/2014/9/9c/UI-Indonesia_Image_SlideLab.jpg" /></li>
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        <li><img src="https://static.igem.org/mediawiki/2014/1/15/UI-Indonesia_Image_SliderHP.jpg" /></li>
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        <li><img src="https://static.igem.org/mediawiki/2014/7/7f/UI-Indonesia_Image_SliderTeam.jpg" /></li>
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<h2>About Our Project</h2>
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<p>Biofilm is a matrix extracellular polymeric substances (EPS) that surrounds microbial colonies and causes more than 65% microbial infections. Most of the pathogenic bacteria could make biofilm that increases their antibiotic resistance and increase its pathogenecity. Our <i>Escherichia coli</i> can degrade biofilm from various bacteria after it seeks them by detecting their quorum sensing signal molecule. Our team focuses in <i>Vibrio cholerae</i> because it causes cholera, one of the deadly tropical country disease. We present our <i>E. coli</i> that can degrade biofilm of <i>V. cholerae</i> after it detects quorum sensing signal molecule from <i>V. cholerae</i>, CAI-1, by CqsS receptor. Then our <i>E. coli</i> will activate motility gene, CheZ, to hunt <i>V. cholerae</i>. When it arrives, our bacteria will degrade the biofilm by secreting enzymes, such as α-amylase, nuclease, and substilisin to break down the matrix and finally secretes peptide 1018 that will kill <i>V. cholerae</i>.
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Our project can be applied in broad application. Not only fighting the <i>Vibrio cholerae</i> but also the other bacteria such as: <i>Pseudomonas aerugoinosa</i>, <i>Bacillus substillis</i>, <i>Klebsiella pneumonia</i>, <i>Staphylococcus aureus</i>, and <i>E. coli</i> Top 10.</p>
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style="color:#000000">Home </a> </td>
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style="color:#000000"> Modeling</a></td>
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style=" color:#000000"> Safety </a></td>
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style="color:#000000"> Attributions </a></td>
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<!-- this is the iGEM logo! it will take to igem.org -->
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<td align ="center"> <a href="https://igem.org/Main_Page"> <img src="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png" width="55px"></a> </td>
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<h3>Welcome ! </h3>
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This is a basic template you may use to customize your wiki, you can take it apart and modify it as much as you want. The links and tabs provided here are basic suggestions, feel free to adapt it for your team and your project. </p>
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If you are looking for general  wiki guidelines, restrictions, design tips and more, visit the <br><a href="https://2014.igem.org/Wiki_How-To"> Wiki How-To Page</a></p>
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<h4> Results</h4>
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<h4>Human Practice</h4>
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<h4>Follow us on Twitter/Facebook!</h4>
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{{:Team:UI-Indonesia/Templates/Footer}}

Latest revision as of 01:54, 18 October 2014

About Our Project

Biofilm is a matrix extracellular polymeric substances (EPS) that surrounds microbial colonies and causes more than 65% microbial infections. Most of the pathogenic bacteria could make biofilm that increases their antibiotic resistance and increase its pathogenecity. Our Escherichia coli can degrade biofilm from various bacteria after it seeks them by detecting their quorum sensing signal molecule. Our team focuses in Vibrio cholerae because it causes cholera, one of the deadly tropical country disease. We present our E. coli that can degrade biofilm of V. cholerae after it detects quorum sensing signal molecule from V. cholerae, CAI-1, by CqsS receptor. Then our E. coli will activate motility gene, CheZ, to hunt V. cholerae. When it arrives, our bacteria will degrade the biofilm by secreting enzymes, such as α-amylase, nuclease, and substilisin to break down the matrix and finally secretes peptide 1018 that will kill V. cholerae.

Our project can be applied in broad application. Not only fighting the Vibrio cholerae but also the other bacteria such as: Pseudomonas aerugoinosa, Bacillus substillis, Klebsiella pneumonia, Staphylococcus aureus, and E. coli Top 10.

Retrieved from "http://2014.igem.org/Team:UI-Indonesia"