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| | + | BIO-COMPASS<hr /> |
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| | + | The aim of our project is to build a brand new bio-navigational system that can be used by the ordinary people. The map information will be coded in DNA strand and do corresponding biochemical operations. The bio-navigational database will establish the relationship between biochemical operation instructions and traditional navigation instructions. In order to reduce workload in advance， BIO-COMPASS can also screen reaction conditions according to the road conditions. Furthermore, we try to update the system to adapt to the more complex path plans. For this, we design some special enzyme sites which differ from standard bio-bricks' as the function interfaces. For example, "Logic Gate" genetic device can be inserted in our system to help us solve the path plan which include a transfer station between the start and the destination. BIO-COMPASS will find the best solution by using a variety of detection methods such as electrophoresis and reporter gene. |
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| - | <td><p >Project descriptions </p>
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| - | <p >In contemporary, sufficient attention are being paid to navigation and road planning with technology and economy developing at a staggering rate.</p>
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| - | <p >Though the <a name="2125570-2-2" id="2125570-2-2" >modern </a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%94%B5%E5%AD%90%E8%AE%A1%E7%AE%97%E6%9C%BA%E6%8A%80%E6%9C%AF" >electronic</a> <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%94%B5%E5%AD%90%E8%AE%A1%E7%AE%97%E6%9C%BA%E6%8A%80%E6%9C%AF" >computer</a> technique and Global Positioning System have given individuals <a name="3592885-0-10" id="3592885-0-10" ></a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%B2%BE%E7%A1%AE%E7%9A%84%E4%BD%8D%E7%BD%AE%E4%BF%A1%E6%81%AF" >accurate</a> <a name="3592885-0-12" id="3592885-0-12" ></a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%B2%BE%E7%A1%AE%E7%9A%84%E4%BD%8D%E7%BD%AE%E4%BF%A1%E6%81%AF" >location</a> <a name="3592885-0-13" id="3592885-0-13" ></a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%B2%BE%E7%A1%AE%E7%9A%84%E4%BD%8D%E7%BD%AE%E4%BF%A1%E6%81%AF" >information</a></p>
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| - | <p > and <a name="11440362-0-4" id="11440362-0-4" ></a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E5%8F%8B%E5%A5%BD%E7%9A%84%E6%93%8D%E4%BD%9C%E7%95%8C%E9%9D%A2" >friendly</a> user <a name="11440362-0-7" id="11440362-0-7" ></a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E5%8F%8B%E5%A5%BD%E7%9A%84%E6%93%8D%E4%BD%9C%E7%95%8C%E9%9D%A2" >interface</a> in our navigator.A multitude of complex path planning tasks still made the <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%94%B5%E5%AD%90%E8%AE%A1%E7%AE%97%E6%9C%BA%E6%8A%80%E6%9C%AF" >electronic</a> <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%94%B5%E5%AD%90%E8%AE%A1%E7%AE%97%E6%9C%BA%E6%8A%80%E6%9C%AF" >computer</a> technique meet a</p>
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| - | <p > serious technical challenge in <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E5%A4%A7%E8%A7%84%E6%A8%A1%E8%AE%A1%E7%AE%97" >Large</a>-<a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E5%A4%A7%E8%A7%84%E6%A8%A1%E8%AE%A1%E7%AE%97" >scale</a>-<a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E5%A4%A7%E8%A7%84%E6%A8%A1%E8%AE%A1%E7%AE%97" >computations</a>.<a name="2010990-4-24" id="2010990-4-24" ></a>The <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E6%B5%B7%E9%87%8F%E8%AE%A1%E7%AE%97" >massive</a> <a name="2010990-4-25" id="2010990-4-25" ></a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E6%B5%B7%E9%87%8F%E8%AE%A1%E7%AE%97" >scale</a> <a name="2010990-4-26" id="2010990-4-26" ></a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E6%B5%B7%E9%87%8F%E8%AE%A1%E7%AE%97" >computing</a> about series of path problems will beyond <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%94%B5%E5%AD%90%E8%AE%A1%E7%AE%97%E6%9C%BA%E6%8A%80%E6%9C%AF" >electronic</a></p>
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| - | <p > <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%94%B5%E5%AD%90%E8%AE%A1%E7%AE%97%E6%9C%BA%E6%8A%80%E6%9C%AF" >computer</a>’s capability. </p>
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| - | <p >Using 4 kinds of <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%A2%B1%E5%9F%BA" >basic</a> groups for saving genetic information is one of the important features about DNA. Based on this, it is possible for us to code </p>
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| - | <p >information in DNA strand and do some corresponding chemical operations. Our plan is to build a standard data base for every possible nodes and</p>
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| - | <p > paths by using biobricks and save them as standard DNA coding.When each path planning tasks upload to our <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E4%BF%A1%E6%81%AF%E5%A4%84%E7%90%86%E4%B8%AD%E5%BF%83" >Information</a> <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E4%BF%A1%E6%81%AF%E5%A4%84%E7%90%86%E4%B8%AD%E5%BF%83" >Processing</a> <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E4%BF%A1%E6%81%AF%E5%A4%84%E7%90%86%E4%B8%AD%E5%BF%83" >Center</a>, first </p>
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| - | <p >we can screen out the suitable paths and nodes by comparing with real-time traffic flow information. In <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E5%8F%8D%E5%BA%94%E5%99%A8" >reaction</a> <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E5%8F%8D%E5%BA%94%E5%99%A8" >vessel</a>, these suitable paths and </p>
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| - | <p >nodes will be mixed and create random pathways by using the ligase.Then we can use the starting point and <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%BB%88%E7%82%B9" >terminal</a> <a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E7%BB%88%E7%82%B9" >point</a>’s DNA coding as the </p>
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| - | <p >primer to screen random pathways. After using bead labeled or sequencing to confirm the details of the node path, we can get specific route plan finally. </p>
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| - | <p > Using DNA molecules as processors, one can compute millions of routes simultaneously, <a name="OLE_LINK4" id="OLE_LINK4" >reducing the time required through this massively parallel</a></p>
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| - | <p ><a name="OLE_LINK4" > approach</a>. Additionally, this kind of BIO-COMPUTING system <a name="6513585-0-10" id="6513585-0-10" >will have much </a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E6%9B%B4%E4%BD%8E%E7%9A%84%E8%83%BD%E8%80%97" >lower</a> power <a name="6513585-0-12" id="6513585-0-12" ></a><a href="http://cn.bing.com/dict/clientsearch?mkt=zh-CN&setLang=zh&form=BDVEHC&ClientVer=BDDTV3.4.0.4311&q=%E6%9B%B4%E4%BD%8E%E7%9A%84%E8%83%BD%E8%80%97" >consumption</a> and less storage space compared with </p>
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| - | <p >traditional computer system. </p>
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