Team:LMU-Munich/Team/Financing

From 2014.igem.org

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Revision as of 00:20, 17 October 2014

Financing

From the very beginning, we knew that an undertaking like the participation in the iGEM competition would be expensive. Not only lab supplies like chemicals and plasticware or the purchase of enzymes and oligonucleotides cost plenty of money, also registration fees for the competition and the Giant Jamboree as well as travel and accommodation costs come at a price. For us students that are normally not concerned by these costs, it was very interesting to see behind the curtains of how much it costs as a 19-person team to participate in such a competition (see pie charts). We like to thank all our generous sponsors for their kind support and also thank all the supporters within the faculty of Biology of the LMU that were always helpful and made our participation in iGEM and our trip to the Giant Jamboree in Boston possible in the first place.

We are deeply grateful for your endorsement!

Hi there!

Welcome to our Wiki! I'm BaKillus, the pathogen-hunting microbe, and I'll guide you on this tour through our project. If you want to learn more about a specific step, you can simply close the tour and come back to it anytime you like. So let's start!

What's the problem?

First of all, what am I doing here? The problem is, pathogenic bacteria all around the world are becoming more and more resistant against antimicrobial drugs. One major reason for the trend is the inappropriate use of drugs. With my BaKillus super powers, I want to reduce this misuse and thus do my part to save global health.

Sensing of pathogens

To combat the pathogenic bacteria, I simply eavesdrop on their communication. Bacteria talk with each other via quorum sensing systems, which I use to detect them and trigger my responses.

Adhesion

The more specific and effective I can use my powers, the lower the danger is of provoking new resistance development. So I catch pathogens whenever I get hold of them and stick to them until my work is done.

Killing

Talking about my work - killing pathogens is finally what I am made for. In response to quorum sensing molecules of the pathogens, I export a range of antimicrobial substances leading to dissipation of biofilms and the killing of the targeted bacteria.

Suicide switch

When the job is done and all the bad guys are finished, you don't need a super hero anymore. So after fulfilling my work I say goodbye to the world by activating my suicide switch.

Application

Of course I'm not only a fictional hero, but a very real one. In two different prototypes, I could be used for diagnosis or treatment of pathogen-caused diseases. However, there is still a whole lot of regulational and economical questions that have to be answered before.

See you!

So now you know my short story - and it is time for me to return to my fight for a safer world. Feel free to take a closer look on my super powers, the process of my development or the plans for a medical application.

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