Team:UCL/FAQ/iGEM

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Latest revision as of 14:46, 16 October 2014

Goodbye Azodye UCL iGEM 2014

The International Genetically Engineered Machine (iGEM) Competition

iGEM is a synthetic biology competition where teams from around the world aim to design and build a biological system out of standardised, interchangeable parts.

The iGEM foundation aids this by creating the Registry of Standard Biological Parts, a library of characterised genetic sequences which perform desired functions. These standardised components (BioBricks) are formatted in a way which enables them to be easily put together so users can mix and match genes to create an organism displaying a unique set of functions. Teams re-use existing BioBricks, as well as designing new ones, in order to create genetically engineered machines.

These engineered systems can potentially be used for a range of applications: from medical uses such as the tailored release of insulin for the treatment of diabetes to resolving global environmental issues by mass production of biofuels from renewable sources.

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This year, the UCL iGEM tackles an environmental problem: the pollution of waterways by industrial azo-dye disposal. This addresses the pressing need to clean up industrial effluents of these carcinogenic derivatives before being released into the environment, and thus keeping our water systems clean.

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UCL has been involved in iGEM since 2009

Previous UCL iGEM teams include Spotless Mind (Gold), Darwin Toolbox, Plastic Republic (Gold), E. coili (Bronze), Hypoxon (Gold), and Stress Busters (Silver).

As a result of competing in iGEM for over 5 years, UCL has developed a community of synthetic biologists. Our team this year has been lucky to benefit from the advice and experience of past iGEM teams, as well as enjoy the summer working alongside students from all disciplines.

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-<div class="textTitle"><h4>An introduction to iGEM</h4></div>
+<div class="textTitle"><h4>The International Genetically Engineered Machine (iGEM) Competition</h4></div>
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+<table style="width:100%" cellpadding="15" data-step="1" data-position='top' data-intro="Many people have asked us what iGEM is all about, and what we've been doing all summer."><col width="60%"><col width="40%">
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-<p>The International Genetically Engineered Machine (iGEM) is a <a href="https://2014.igem.org/Team:UCL/FAQ/Synbio">synthetic biology</a> competition where <a href="https://igem.org/Team_List?year=2014">teams</a> from around the <a1 data-tip="true" class="top large" data-tip-content="This year, 245 teams from 4 continents will be meeting in Boston to present their work at the Giant Jamboree." href="javascript:void(0)"><b>world</b></a> aim to design and build a biological system out of standardised, interchangeable parts.</p>
+<p>iGEM is a <a href="https://2014.igem.org/Team:UCL/FAQ/Synbio">synthetic biology</a> competition where <a href="https://igem.org/Team_List?year=2014">teams</a> from around the <a1 data-tip="true" class="top large" data-tip-content="This year, 245 teams from 4 continents will be meeting in Boston to present their work at the Giant Jamboree." href="javascript:void(0)"><b>world</b></a> aim to design and build a biological system out of standardised, interchangeable parts.</p>
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 <p>The <a href="http://www.igem.org/Main_Page">iGEM</a> foundation aids this by creating the <a href="http://parts.igem.org/Main_Page">Registry of Standard Biological Parts</a>, a library of characterised genetic sequences which perform desired functions. These standardised components (<a href="https://2014.igem.org/Team:UCL/Project/Biobricks">BioBricks</a>) are formatted in a way which enables them to be easily put together so users can mix and match genes to create an organism displaying a unique set of functions. Teams re-use existing BioBricks, as well as designing new ones, in order to create genetically engineered machines.</p>
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-<p>This year, the UCL iGEM team attempts to tackle an environmental problem: the pollution of waterways by industrial azo-dye disposal. This addresses the pressing need to clean up industrial effluents of these carcinogenic derivatives before being released into the environment, and thus keeping our water systems clean.</p>
+<p>
+<a data-tip="true" class="top large" data-tip-content="Our project this year has encompassed various aspects; from synbio in the lab (constructing and characterising BioBricks), to public engagement (hosting a key stakeholder event with over 100 attendees)." href="javascript:void(0)" style="width: 32%;float: right;margin-left:2%"><img src="https://static.igem.org/mediawiki/2014/3/3d/UCLteammeetingSCJ.JPG" style="max-width: 100%;"></a>
+This year, the UCL iGEM tackles an environmental problem: the pollution of waterways by industrial azo-dye disposal. This addresses the pressing need to clean up industrial effluents of these carcinogenic derivatives before being released into the environment, and thus keeping our water systems clean.</p>
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+<div class="SCJMFHIGHLIGHT" data-step="2" data-position='top' data-intro="A special thanks to the past UCL iGEM teams, and a special thanks to Dr Darren Nesbeth for his coaching.">
 <h4>UCL has been involved in iGEM since 2009</h4>
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-<a data-tip="true" class="top large" data-tip-content="Spotless Mind, UCL iGEM 2013. Alex and Andy have been actively helping us this year." href="javascript:void(0)" style="width: 32%;float: left;margin-left:0%"><img src="https://static.igem.org/mediawiki/2014/3/3d/SPOTM.jpg" style="max-width: 100%;"></a>
+<a data-tip="true" class="top large" data-tip-content="Spotless Mind, UCL iGEM 2013. Alex and Andy have been actively helping us this year." href="javascript:void(0)" style="width: 32%;float: left;margin-left:0%;margin-bottom:1%"><img src="https://static.igem.org/mediawiki/2014/3/3d/SPOTM.jpg" style="max-width: 100%;"></a>
 <a data-tip="true" class="top large" data-tip-content="Plastic Republic, UCL iGEM 2012. They tackled an environmental issue, just like we are." href="javascript:void(0)" style="width: 32%;float: left;margin-left:2%;margin-right:2%"><img src="https://static.igem.org/mediawiki/2014/c/c0/PLASTR.jpg" style="max-width: 100%;"></a>
-<a data-tip="true" class="top large" data-tip-content="Plastic Republic, UCL iGEM 2012. Philipp has been advising us this year." href="javascript:void(0)" style="width: 32%;float: left;margin-right:0%"><img src="https://static.igem.org/mediawiki/2014/e/e1/ECOIL.jpg" style="max-width: 100%;"></a>
+<a data-tip="true" class="top large" data-tip-content="Plastic Republic, UCL iGEM 2012. Philipp has been advising us this year." href="javascript:void(0)" style="width: 32%;float: left;margin-right:0%;margin-bottom:1%"><img src="https://static.igem.org/mediawiki/2014/e/e1/ECOIL.jpg" style="max-width: 100%;"></a>
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 Previous UCL iGEM teams include <a data-tip="true" class="top large" data-tip-content="In 2013, we explored the potential application genetic engineering techniques on the brain, using synthetic biology to cure Alzheimer's disease." href="https://2013.igem.org/Team:UCL"><b>Spotless Mind</b></a> (Gold), <a data-tip="true" class="top large" data-tip-content="In 2013, our entrepreneurship team built a safe, user-friendly, affordable biotechnology laboratory in a beautiful 13 x 11 inch box, containing a centrifuge, a PCR machine and a gel electrophoresis unit inclusive with transilluminator." href="https://2013.igem.org/Team:UCL_E"><b>Darwin Toolbox</b></a>, <a data-tip="true" class="top large" data-tip-content="In 2012, we designed a synthetic biology approach for the bioremediation of micro-plastic pollutants within the marine environment, with emphasis on regions of excessive debris accumulation, such as the North Pacific ‘garbage patch’." href="https://2012.igem.org/Team:UCL_London"><b>Plastic Republic</b></a> (Gold), <a data-tip="true" class="top large" data-tip-content="In 2011, we used supercoiliology to increase the production quantity of supercoiled target plasmids by over-expressing the enzyme gyrase, a unique topoisomerase that regulates the topology of DNA molecules." href="https://2011.igem.org/Team:UCL_London"><b>E. coili</b></a> (Bronze), <a data-tip="true" class="top large" data-tip-content="In 2010, we aimed to create cells capable of self-induction into the production phase, without the introduction of any chemical into the closed system." href="https://2010.igem.org/Team:UCL_London"><b>Hypoxon</b></a> (Gold), and <a data-tip="true" class="top large" data-tip-content="In 2009, we produced a series of synthetic biosensor devises, which can improve on the traditional sensors in bioprocessing, using a system called 'The Traffic Light Stress Sensor'." href="https://2009.igem.org/Team:UCL_London"><b>Stress Busters</b></a> (Silver).</p>
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