Team:Valencia Biocampus/Modeling temp2

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<script type="text/javascript">var activeSection = "modeling";</script>
<script type="text/javascript">var activeSection = "modeling";</script>
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<link rel="stylesheet" type="text/css" href="https://2014.igem.org/wiki/index.php?title=Template:Team:Valencia_Biocampus/Templates/css/bootstrap-slider&amp;action=raw&amp;ctype=text/css" />
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<script type="text/javascript" src="https://2014.igem.org/wiki/index.php?title=Template:Team:Valencia_Biocampus/Templates/js/bootstrap-slider&amp;action=raw&amp;ctype=text/javascript"></script>
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   <div class="container withBackground">  
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<div class="contentWithPadding">
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= Modeling =
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Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nam cursus purus eget ex porta, sed efficitur massa congue. Donec eleifend enim vulputate, suscipit lorem ut, dictum sem. Donec in eros id dolor egestas gravida. Nulla varius rutrum orci pretium tempor. Sed quam massa, maximus nec velit nec, malesuada ornare sem. Ut non efficitur ante. Phasellus non rhoncus nunc. Mauris tempus volutpat sem, quis mattis ligula iaculis nec. Quisque fringilla vulputate aliquam. Integer vitae magna et lacus hendrerit feugiat sed id augue. Duis euismod massa nec pulvinar pulvinar. Sed at ultrices sapien.
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<div class="col-sm-9 center-block" style="padding:20px;">
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    The modelling sub-team aims to predict the main features of our project to understand how stable, standard and orthogonal engineered systems are. In order
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<p>Move the cursor to a given expression rate (fraction of the maximum shown in the red box) and generate a chain</p>
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    to accomplish this goal, two different approaches have been taken into account: mRNA and protein expression levels prediction tools and plasmid dynamics.
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    These two approaches may give insight of the presented problem.<u></u><u></u>
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      <input id="sliderApp" type="text" data-slider-min="0" data-slider-max="100" data-slider-step="1" data-slider-value="25" />
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      <span class="label label-success" id="percent1">25%</span>
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<p>
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    In order to predict accurately the mRNA and protein expression levels, we propose a model considering both intrinsic (metabolic burden) and extrinsic (pH
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      <input type="hidden" name="textbox1" id="textbox1" value="25"/>  
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    or temperature) characteristics of our system. Using this model, we aim to describe the bacterial response to different kind of stresses (<em>e.g.</em>
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<br/><br/>
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    temperature, pH, UV radiation).<u></u><u></u>
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      <button type="button" name="button" id="button1" data-loading-text="Generating..." class="btn btn-default">Generate chain</button>
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<p>
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    A second approach tries to predict the behaviour of two different plasmids sharing the same origin of replication in a single cell. As they share the same
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    mechanism of regulation, they may behave in a non-orthogonal way. The model is based in stochastic dynamics (how perturbations may become a relevant
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    feature of the system) using both simulation and analysis tools.<u></u><u></u>
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    While both models are different, we want to create a framework to gain knowledge in engineered molecular biological systems, explaining our experimental
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    results and proposing new hypothesis, to design more reliable and predictable biological machines.
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</p>
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<br/>
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<p class="text-centered">Promoter sequence (from -41 to -1 nt) is:</p>
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                <p id="output"></p>
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                <p class="text-centered">Calculated value is:
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                    <span class="label label-danger" id="percent2"></span>
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                </p>
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<script type="text/javascript" src="https://2014.igem.org/wiki/index.php?title=Template:Team:Valencia_Biocampus/Templates/js/NewModelingApp&amp;action=raw&amp;ctype=text/javascript"></script>
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<script type="text/javascript">
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$("#sliderApp").slider({
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formatter: function(value) {
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return  value+'%';
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}
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});
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$("#sliderApp").on("slide", function(slideEvt) {
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    if(slideEvt.value === undefined)
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        slideEvt.value = 0;
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    $("#textbox1").val(slideEvt.value);   
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    $("#percent1").text(slideEvt.value+'%');
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});
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  $('#button1').click(function () {
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    $("#input").empty();
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    $(this).prop("disabled",true);
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    $(this).text("GENERATING ...");
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    CE();
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  });
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</script>
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Vestibulum feugiat tincidunt lectus eget faucibus. Integer ut elementum nisi. Cras dignissim malesuada augue sit amet condimentum. Nullam eu dui eros. Cras vulputate congue tellus, vel malesuada ipsum rhoncus quis. Phasellus et nibh id dui pulvinar rhoncus. Sed tincidunt ex a felis rhoncus, vel posuere nisl dictum.
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Vestibulum sed commodo leo, finibus ultricies erat. Vivamus et dictum diam, sed rhoncus enim. Pellentesque eu justo dignissim, pellentesque lacus ac, porta lectus. Pellentesque leo ante, sagittis in leo a, consectetur vehicula libero. Quisque at volutpat dolor. Nulla sit amet euismod ex. Cras convallis vel nisi et consequat. Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Aliquam vitae porta nulla, eu sodales nisl. Sed convallis ullamcorper massa a viverra. Aliquam eleifend efficitur arcu. Fusce vulputate sem urna, varius elementum leo tincidunt laoreet. Quisque sagittis non turpis non faucibus. Duis scelerisque consectetur nisl, a convallis lectus fermentum eget.
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Aliquam massa nisl, fermentum non bibendum vel, iaculis eu augue. Pellentesque ultrices purus id vestibulum dictum. Aenean vel rutrum mauris. Donec commodo, augue vel molestie vehicula, dolor ipsum porttitor lectus, blandit volutpat erat enim non lectus. Sed enim sem, eleifend eu ex ac, molestie molestie nunc. Fusce gravida leo in metus vestibulum, id mollis est convallis. Mauris ac consectetur nulla. Nullam tristique sapien tellus, aliquam porta enim maximus eget. Etiam eleifend consectetur augue in vehicula. Vestibulum ante ipsum primis in faucibus orci luctus et ultrices posuere cubilia Curae; Suspendisse vitae dignissim tortor. Aliquam erat volutpat.
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Nullam tortor ex, dictum vitae ultricies sollicitudin, finibus id nunc. Vivamus rutrum metus eu quam vulputate pellentesque. Praesent ornare velit quis felis dapibus, et fringilla ante ullamcorper. Suspendisse et tellus consectetur est consequat aliquet. Mauris molestie scelerisque diam, quis pulvinar mi fringilla ut. Sed efficitur dignissim facilisis. Vivamus nec varius nulla. Praesent porttitor massa tempus enim consequat, faucibus fringilla lorem viverra. Nullam porta tortor et dui iaculis, accumsan semper ipsum mattis. Curabitur auctor turpis a orci euismod consectetur. Maecenas nisi orci, ullamcorper venenatis mi sed, pretium dictum nisl. Nulla lacinia fringilla eros ac venenatis.
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Latest revision as of 07:31, 16 October 2014

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Nam cursus purus eget ex porta, sed efficitur massa congue. Donec eleifend enim vulputate, suscipit lorem ut, dictum sem. Donec in eros id dolor egestas gravida. Nulla varius rutrum orci pretium tempor. Sed quam massa, maximus nec velit nec, malesuada ornare sem. Ut non efficitur ante. Phasellus non rhoncus nunc. Mauris tempus volutpat sem, quis mattis ligula iaculis nec. Quisque fringilla vulputate aliquam. Integer vitae magna et lacus hendrerit feugiat sed id augue. Duis euismod massa nec pulvinar pulvinar. Sed at ultrices sapien.

Move the cursor to a given expression rate (fraction of the maximum shown in the red box) and generate a chain

25%


Promoter sequence (from -41 to -1 nt) is:

Calculated value is:

Vestibulum feugiat tincidunt lectus eget faucibus. Integer ut elementum nisi. Cras dignissim malesuada augue sit amet condimentum. Nullam eu dui eros. Cras vulputate congue tellus, vel malesuada ipsum rhoncus quis. Phasellus et nibh id dui pulvinar rhoncus. Sed tincidunt ex a felis rhoncus, vel posuere nisl dictum. Vestibulum sed commodo leo, finibus ultricies erat. Vivamus et dictum diam, sed rhoncus enim. Pellentesque eu justo dignissim, pellentesque lacus ac, porta lectus. Pellentesque leo ante, sagittis in leo a, consectetur vehicula libero. Quisque at volutpat dolor. Nulla sit amet euismod ex. Cras convallis vel nisi et consequat. Cum sociis natoque penatibus et magnis dis parturient montes, nascetur ridiculus mus. Aliquam vitae porta nulla, eu sodales nisl. Sed convallis ullamcorper massa a viverra. Aliquam eleifend efficitur arcu. Fusce vulputate sem urna, varius elementum leo tincidunt laoreet. Quisque sagittis non turpis non faucibus. Duis scelerisque consectetur nisl, a convallis lectus fermentum eget. Aliquam massa nisl, fermentum non bibendum vel, iaculis eu augue. Pellentesque ultrices purus id vestibulum dictum. Aenean vel rutrum mauris. Donec commodo, augue vel molestie vehicula, dolor ipsum porttitor lectus, blandit volutpat erat enim non lectus. Sed enim sem, eleifend eu ex ac, molestie molestie nunc. Fusce gravida leo in metus vestibulum, id mollis est convallis. Mauris ac consectetur nulla. Nullam tristique sapien tellus, aliquam porta enim maximus eget. Etiam eleifend consectetur augue in vehicula. Vestibulum ante ipsum primis in faucibus orci luctus et ultrices posuere cubilia Curae; Suspendisse vitae dignissim tortor. Aliquam erat volutpat. Nullam tortor ex, dictum vitae ultricies sollicitudin, finibus id nunc. Vivamus rutrum metus eu quam vulputate pellentesque. Praesent ornare velit quis felis dapibus, et fringilla ante ullamcorper. Suspendisse et tellus consectetur est consequat aliquet. Mauris molestie scelerisque diam, quis pulvinar mi fringilla ut. Sed efficitur dignissim facilisis. Vivamus nec varius nulla. Praesent porttitor massa tempus enim consequat, faucibus fringilla lorem viverra. Nullam porta tortor et dui iaculis, accumsan semper ipsum mattis. Curabitur auctor turpis a orci euismod consectetur. Maecenas nisi orci, ullamcorper venenatis mi sed, pretium dictum nisl. Nulla lacinia fringilla eros ac venenatis.

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