Team:Saarland

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    <span id="countdown" style="color: #502204; font: normal 24px/40px Arial,sans-serif;"></span> left to World Wiki Freeze<br>
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<a href="https://2014.igem.org/Team:Saarland/rpg">
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<h1 >WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:Saarland&action=edit"style="color:#FFFFFF"> Click here  to edit this page!</a> </p>
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<h1>Project Rufus or the Force of the Naked Mole Rat</h1>
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Cancer is not only one of the most common diagnoses, but also the leading cause of death worldwide. There are only limited therapeutic possibilities and these are mostly associated with adverse effects. A special form of hyaluronic acid has the potential to become an innovative therapeutic drug for the treatment of cancer. Originally discovered in connective tissues of <i>Heterocephalus glaber</i> this high-molecular-mass hyaluronic acid (HMM-HA) is supposed to mediate the cancer resistance in this species. Our aim is to employ a simple soil bacterium as an expression system for the first ever biotechnological production of this HMM-HA. After purification we want to test and further characterise its inhibitory effect on carcinogenesis in selected human cancer cell lines. We are confident that the anti carcinogenic properties and high biocompatibility of our synthesised HMM-HA will herald a new age of fighting cancer.
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<h3> Follow the steps below to join the "Anti-Cancer Rebels" </h3>
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<i> Click on the pictures to learn more</i><br>
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<a href="https://2014.igem.org/Team:Saarland/anticancergens#thenackedmolerat">
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<img src="https://static.igem.org/mediawiki/2014/7/79/Welcome_Step3.png"width="444px"> </a>
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<a href="https://2014.igem.org/Team:Saarland"style="color:#000000">Home </a> </td>
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<a href="https://2014.igem.org/Team:Saarland/4_step">
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<a href="https://2014.igem.org/Team:Saarland/Team"style="color:#000000"> Team </a> </td>
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<a href="https://igem.org/Team.cgi?year=2014&team_name=Saarland"style="color:#000000"> Official Team Profile </a></td>
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<a href="https://2014.igem.org/Team:Saarland/Project"style="color:#000000"> Project</a></td>
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<a href="https://2014.igem.org/Team:Saarland/Parts"style="color:#000000"> Parts</a></td>
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<a href="https://2014.igem.org/Team:Saarland/Modeling"style="color:#000000"> Modeling</a></td>
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<a href="https://2014.igem.org/Team:Saarland/Notebook"style="color:#000000"> Notebook</a></td>
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<a href="https://2014.igem.org/Team:Saarland/Attributions"style="color:#000000"> Attributions </a></td>
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<p> Please be sure to keep these links, your audience will want to find your: </p>
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<li><a href="https://2014.igem.org/Team:Saarland">Home</a> </li>
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<li><a href="https://2014.igem.org/Team:Saarland/Team">Team</a> </li>
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=Saarland">Official Team Profile</a> </li>
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<li><a href="https://2014.igem.org/Team:Saarland/Project">Project</a> </li>
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<li><a href="https://2014.igem.org/Team:Saarland/Parts">Parts</a> </li>
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<li><a href="https://2014.igem.org/Team:Saarland/Safety">Safety</a> </li>
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<p>There are a few wiki requirements teams must follow:</p>
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<li>All pages, images and files must be hosted on the <a href ="https://2014.igem.org/Special:Upload">  2014.igem.org server</a>. </li>
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<li>All pages must be created under the team’s name space.</li>
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<li>As part of your documentation, keep the links from the menu to the left. </li>
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<li>Do not use flash in wiki code. </li>
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<li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
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<p>Visit the <a href="https://2014.igem.org/Wiki_How-To"> Wiki How To page </a> for a complete list of requirements, tips and other useful information. </p>
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<p>We are currently working on providing teams with some easy to use design templates.
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a> lists. </p>
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<iframe src="//player.vimeo.com/video/109005558" width="500" height="281" frameborder="0" webkitallowfullscreen mozallowfullscreen allowfullscreen></iframe> <p><a href="http://vimeo.com/109005558">Saarland University iGEM 2014 - Campus Tour</a> </p> </div></html>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
 
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and what you plan to do.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="">iGEM 2013 calendar</a> </li>
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<li>Have lots of fun! </li>
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Latest revision as of 21:17, 17 October 2014

0 visitors
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Project Rufus or the Force of the Naked Mole Rat

Cancer is not only one of the most common diagnoses, but also the leading cause of death worldwide. There are only limited therapeutic possibilities and these are mostly associated with adverse effects. A special form of hyaluronic acid has the potential to become an innovative therapeutic drug for the treatment of cancer. Originally discovered in connective tissues of Heterocephalus glaber this high-molecular-mass hyaluronic acid (HMM-HA) is supposed to mediate the cancer resistance in this species. Our aim is to employ a simple soil bacterium as an expression system for the first ever biotechnological production of this HMM-HA. After purification we want to test and further characterise its inhibitory effect on carcinogenesis in selected human cancer cell lines. We are confident that the anti carcinogenic properties and high biocompatibility of our synthesised HMM-HA will herald a new age of fighting cancer.


Follow the steps below to join the "Anti-Cancer Rebels"

Click on the pictures to learn more


Tiny timelapse


Retrieved from "http://2014.igem.org/Team:Saarland"