Team:CityU HK

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<h1>WELCOME TO iGEM 2014! </h1>
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<p>Your team has been approved and you are ready to start the iGEM season!
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<br>On this page you can document your project, introduce your team members, document your progress <br> and share your iGEM experience with the rest of the
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world! </p>
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<p style="color:#E7E7E7"> <a href="https://2014.igem.org/wiki/index.php?title=Team:CityU_HK&action=edit"style="color:#FFFFFF"> Click here  to edit this page!
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    <li> <a href="https://2014.igem.org/Team:CityU_HK"><img src="https://static.igem.org/mediawiki/2014/e/ea/IGEM_wiki_logo_home.jpg" width="158" height="99"></a>  
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     <a href="https://2014.igem.org/Team:CityU_HK/Team"><img src="https://static.igem.org/mediawiki/2014/c/ce/IGEM_wiki_logo_team.jpg" width="158" height="99"> </a>
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        <li><a href="https://igem.org/Team.cgi?year=2014&team_name=CityU_HK">Team Members</a></li>
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        <li><a href="https://igem.org/Team.cgi?year=2014&team_name=CityU_HK">Advisors</a></li>
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        <li><a href="https://igem.org/Team.cgi?year=2014&team_name=CityU_HK">Acknowledgement</a></li>
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        <a id="btn-custom" href="#Lower" id="#Lower class="anchorLink"><button class="btn btn-custom">ABSTRACT</button></a>
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         <li><a href="https://igem.org/Team.cgi?year=2014&team_name=CityU_HK">Abstract</a></li>
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        <li><a href="https://igem.org/Team.cgi?year=2014&team_name=CityU_HK">Modules Description</a></li>
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        <li><a href="https://igem.org/Team.cgi?year=2014&team_name=CityU_HK">Data Pages</a></li>
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        <li><a href="https://igem.org/Team.cgi?year=2014&team_name=CityU_HK">Notebook</a></li>
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        <li><a href="https://igem.org/Team.cgi?year=2014&team_name=CityU_HK">Blog</a></li>
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    <h2>Abstract</h2>
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    <p><b>Obesity</b> has now reached epidemic proportions worldwide, which has serious consequences because obesity is associated with various chronic human diseases such as diabetes, hypertension and cardiovascular diseases. With the aim to protect oneself against obesity and debilitating diseases caused by a high-fat diet, we are using a synthetic biology approach to design an <i>Escherichia coli</i> strain (called <b><font color=#3cc>Fit. Coli</font></b>) that has an enhanced ability to uptake and convert excess fatty acids from fatty foods into a-linolenic acid (ALA). The strategy is to engineer the <i>fadL</i> and <i>fadD</i> genes along with three desaturase genes to facilitate the uptake of long-chain fatty acids and their biotransformation to ALA by the “Fit. Coli” strain. It is predicted that the ALA converted from excess fatty acids by Fit. Coli is converted to docosahexaenoic acid (DHA), an omega-3-fatty acid, in the human gut, which is well known to have many positive health benefits.</p>
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<p> Please be sure to keep these links, your audience will want to find your: </p>
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<!--==================== footer ===========================-->
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<div id="footer" class="row">
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<div class="col-md-7">
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      <h3>Sponsors</h3>
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      <a href="http://www.cityu.edu.hk/" target="_blank"><img src="https://static.igem.org/mediawiki/2014/9/9c/CityU_HK_citylogo.png" width="95"></a>
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    <a href="http://www6.cityu.edu.hk/bhdbapp/deptweb/index.html" target="_blank"><img src="https://static.igem.org/mediawiki/2014/9/98/CityU_HK_bchlogo.png" width="80"></a>
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      <img src="https://static.igem.org/mediawiki/2014/b/b1/CityU_HK_Invitrogen.png" width="100">
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    <img src="https://static.igem.org/mediawiki/2014/7/7a/CityU_HK_Neblogocol.png" width="135">
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    <img src="https://static.igem.org/mediawiki/2014/d/dc/CityU_HK_IDT-Logo.png" width="125">
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</div> <!-- end of col-md-7-->
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      <h3>Stay connected!</h3>
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<li><a href="https://2014.igem.org/Team:CityU_HK">Home</a> </li>
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      <p>email: <a href="mailto:cityuhk.igem@gmail.com">cityuhk.igem@gmail.com</a></p>
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<li><a href="https://2014.igem.org/Team:CityU_HK/Team">Team</a> </li>
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      <a href="http://www.facebook.com/igem.2014CityU"><img src="https://static.igem.org/mediawiki/2014/3/31/CityU_HK_fb_logo.png" width="50" height="48"></a>
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=CityU_HK">Official Team Profile</a> </li>
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      <a href="http://twitter.com/CityUHK_iGEM"><img src="http://ibo2014.org/wordpress/wp-content/themes/ibo2014/img/navbar/twitter_icon.png" width="49" height="51"></a>
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<li><a href="https://2014.igem.org/Team:CityU_HK/Project">Project</a> </li>
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      <a href="http://www.youtube.com/channel/UC0_bUWwafB4m0K6mFdXN7-w"><img src="https://static.igem.org/mediawiki/2014/1/12/CityU_HK_youtube_logo.png" width="52" height="50"></a>
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<li><a href="https://2014.igem.org/Team:CityU_HK/Parts">Parts</a> </li>
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<li><a href="https://2014.igem.org/Team:CityU_HK/Modeling">Modeling</a> </li>
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<li><a href="https://2014.igem.org/Team:CityU_HK/Notebook">Notebook</a> </li>
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<li><a href="https://2014.igem.org/Team:CityU_HK/Safety">Safety</a> </li>
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<li><a href="https://2014.igem.org/Team:CityU_HK/Attributions">Attributions</a> </li>
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<p>Copyright &copy; iGEM CityU HK 2014. All Rights Reserved</p>
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<p>There are a few wiki requirements teams must follow:</p>
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<li>All pages, images and files must be hosted on the <a href ="https://2014.igem.org/Special:Upload">  2014.igem.org server</a>. </li>
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<li>All pages must be created under the team’s name space.</li>
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<li>As part of your documentation, keep the links from the menu to the left. </li>
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<li>Do not use flash in wiki code. </li>
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<li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a
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href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
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<p>Visit the <a href="https://2014.igem.org/Wiki_How-To"> Wiki How To page </a> for a complete list of requirements, tips and other useful information. </p>
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<p>We are currently working on providing teams with some easy to use design templates.
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?
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year=2012">iGEM 2012 web sites</a>  lists. </p>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and what you plan to do.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines
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visit the <a href="">iGEM 2013 calendar</a> </li>
 
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Latest revision as of 00:22, 18 October 2014

Bootstrap 101 Template

Abstract

Obesity has now reached epidemic proportions worldwide, which has serious consequences because obesity is associated with various chronic human diseases such as diabetes, hypertension and cardiovascular diseases. With the aim to protect oneself against obesity and debilitating diseases caused by a high-fat diet, we are using a synthetic biology approach to design an Escherichia coli strain (called Fit. Coli) that has an enhanced ability to uptake and convert excess fatty acids from fatty foods into a-linolenic acid (ALA). The strategy is to engineer the fadL and fadD genes along with three desaturase genes to facilitate the uptake of long-chain fatty acids and their biotransformation to ALA by the “Fit. Coli” strain. It is predicted that the ALA converted from excess fatty acids by Fit. Coli is converted to docosahexaenoic acid (DHA), an omega-3-fatty acid, in the human gut, which is well known to have many positive health benefits.

Retrieved from "http://2014.igem.org/Team:CityU_HK"