Team:Caltech/Notebook
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<p>Our project was split into 3 subprojects: AgrBDCA signal reception, FsrABC signal reception, and Ligand export systems.</p> | <p>Our project was split into 3 subprojects: AgrBDCA signal reception, FsrABC signal reception, and Ligand export systems.</p> | ||
<h3>AgrBDCA Signal Reception</h3> | <h3>AgrBDCA Signal Reception</h3> | ||
+ | AgrBDCA is a quorum sensing system found to regulate virulence factors in Staphylococcus Aurea. (sp?) In this system, agrC and agrA function as a histidine kinase receptor and a response regulator respectively. | ||
<h3>FsrABC Signal Reception</h3> | <h3>FsrABC Signal Reception</h3> | ||
+ | FsrABC is another quorum sensing system found to regulate virulence factors in Entereococcus Faecialis (sp?). In this system, FsrC and FsrA function as histidine kinase receptor and response regulator respectively. FsrB is a membrane protein that is processed to form a cyclic 11-amino-acid polypeptide <!-- add a tag here that brings you down to Ligand export systems section -->(see Ligand Export Systems). | ||
<h3>Ligand Export Systems</h3> | <h3>Ligand Export Systems</h3> | ||
+ | With the AgrBDCA system, it is believed that agrB is a membrane protein that exports and modifies a short polypeptide sequence into a polypeptide ligand to be bound by agrC, the histidine kinase receptor. | ||
</td> | </td> | ||
Revision as of 00:56, 3 July 2014
WELCOME TO iGEM 2014!Your team has been approved and you are ready to start the iGEM season!
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Notebook | ||||||||||||
Overview Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 Week 7 Week 8 Week 9 Week 10 Week 11 Week 12 |
Project OverviewOur project was split into 3 subprojects: AgrBDCA signal reception, FsrABC signal reception, and Ligand export systems. AgrBDCA Signal ReceptionAgrBDCA is a quorum sensing system found to regulate virulence factors in Staphylococcus Aurea. (sp?) In this system, agrC and agrA function as a histidine kinase receptor and a response regulator respectively.FsrABC Signal ReceptionFsrABC is another quorum sensing system found to regulate virulence factors in Entereococcus Faecialis (sp?). In this system, FsrC and FsrA function as histidine kinase receptor and response regulator respectively. FsrB is a membrane protein that is processed to form a cyclic 11-amino-acid polypeptide (see Ligand Export Systems).Ligand Export SystemsWith the AgrBDCA system, it is believed that agrB is a membrane protein that exports and modifies a short polypeptide sequence into a polypeptide ligand to be bound by agrC, the histidine kinase receptor. |