Team:Aachen/Project/2D Biosensor
From 2014.igem.org
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- | ''Cellock Holmes'' is devised based upon a SynBio approach comprised of a '''two-dimensional biosensor and a measurement device'''. The two-dimensional biosensor is designed to recognize quorum sensing molecules secreted by the pathogen cells and to generate a distinct fluorescence signal, while the measurement device is designed to recognize and analyse the produced signal. In general different detection mechanisms | + | ''Cellock Holmes'' is devised based upon a SynBio approach comprised of a '''two-dimensional biosensor and a measurement device'''. The two-dimensional biosensor is designed to recognize quorum sensing molecules secreted by the pathogen cells and to generate a distinct fluorescence signal, while the measurement device is designed to recognize and analyse the produced signal. In general different detection mechanisms could be incorporated into the sensing cells, e.g. our fluorescence based [https://2014.igem.org/Team:Aachen/Project/FRET_Reporter REACh construct] or our [https://2014.igem.org/Team:Aachen/Project/Gal3 Galectin-3 construct]. |
Our '''sensor cells are immobilized in agar chips'''. To make the chips, we mix the sensing cells, also known as ''Cellocks'', with liquid LB agar. | Our '''sensor cells are immobilized in agar chips'''. To make the chips, we mix the sensing cells, also known as ''Cellocks'', with liquid LB agar. |
Revision as of 11:02, 15 October 2014
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