Team:Paris Saclay

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===Project Abstract: This is not a lemon!===
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[[File:Paris_Saclay_university.png|200px|right|link=http://www.u-psud.fr/]]
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Synthetic Biology has the power of potentially changing paradigms of society such as our conception of what living beings are. If we deprive bacteria from all their “unnecessary" functions and have them produce what we need and desire, do these bacteria still possess the status of living organisms or have they become machines?
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To raise and explore this question, we adopted an artistic approach. Indeed, we think that '''Bio-Art''' is one of the best ways to reach the citizens and to spark debate and reflection.
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We decided to create a concept organism that would reflect these interrogations. We plan to modify ''Escherichia coli'' in order to produce the '''fragrance''' of a lemon and simulate the '''ripening''' process of a lemon by changing its color gradually from green to yellow. A mixture of bacteria and solid growth medium will be moulded in a lemon '''shape''': it will smell like a lemon, ripe like a lemon and look like a lemon, but "ceci n’est pas un citron” - this is not a lemon… or is it?
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<tr><td bgColor="#e7e7e7" colspan="3" height="1px">Page under construction. Our team is working hard and excited to develop a very good Wiki.</tr>
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With this project we invite everyone to think about the upcoming opportunities and the necessary ethical limits of designing living beings.
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<p> Please be sure to keep these links, your audience will want to find your: </p>
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When life gives you lemons, break your taboos with Paris Saclay!
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A Biologia Sintética tem o poder de mudar os paradigmas da sociedade, como a nossa concepção do que são serem vivos. Se privarmos uma bactéria de todas as suas funções "desnecessárias" e a fizermos produzir o que precisamos e queremos, essa bactéria continuará com um status de organismo vivo ou ela tende a ser uma máquina? Para levantar e explorar essa questão, adotamos uma abordagem artística. De fato, pensamos que '''Bio-Arte''' é uma das melhores maneiras de atingir o grande público e estimar o debate.
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Nós decidimos criar um organismo conceito que refletiria essas interrogações. Nós planejamos modificar ''Escherichia coli'' para que essa produza o '''aroma''' e simule o amadurecimento de um limão, mudando gradualmente sua cor do verde para o amarelo. A mistura de bactérias e meio de cultivo serão moldados em uma forma de limão: ele vai cheirar como um limão, '''amadurecer''' como um limão e ter a '''forma''' de um limão, mas "ceci n'est pas un citron" - isto não é um limão... ou é?  
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Assim, convidamos todos a pensar sobre as perspectivas e limites éticos de projetas seres vivos.
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<li><a href="https://2014.igem.org/Team:Paris_Saclay">Home</a> </li>
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<li><a href="https://2014.igem.org/Team:Paris_Saclay/Team">Team</a> </li>
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=Paris_Saclay">Official Team Profile</a> </li>
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<li><a href="https://2014.igem.org/Team:Paris_Saclay/Project">Project</a> </li>
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<li><a href="https://2014.igem.org/Team:Paris_Saclay/Parts">Parts</a> </li>
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<li><a href="https://2014.igem.org/Team:Paris_Saclay/Modeling">Modeling</a> </li>
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<li><a href="https://2014.igem.org/Team:Paris_Saclay/Notebook">Notebook</a> </li>
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<li><a href="https://2014.igem.org/Team:Paris_Saclay/Safety">Safety</a> </li>
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<li><a href="https://2014.igem.org/Team:Paris_Saclay/Attributions">Attributions</a> </li>
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Quando iGEM Paris-Saclay lhe der limões, quebre seus tabus!
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<p>There are a few wiki requirements teams must follow:</p>
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''This abstract was translated to Portuguese by [https://2014.igem.org/Team:Brasil-SP iGEM Brasil-SP] under our [https://2014.igem.org/Team:Paris_Saclay/Outreach/Collaborations collaborations].''
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<li>All pages, images and files must be hosted on the <a href ="https://2014.igem.org/Special:Upload">  2014.igem.org server</a>. </li>
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<li>All pages must be created under the team’s name space.</li>
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合成生物学有着改变社会的能力,举个例子,所谓的改变社会,就是我们对于地球上生物的认知。
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<li>As part of your documentation, keep the links from the menu to the left. </li>
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<li>The <a href="https://static.igem.org/mediawiki/igem.org/6/60/Igemlogo_300px.png"> iGEM logo </a> should be placed on the upper part of every page and should link to <a href="https://2014.igem.org/Main_Page">2014.igem.org</a>.</li>
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<p>Visit the <a href="https://2014.igem.org/Wiki_How-To"> Wiki How To page </a> for a complete list of requirements, tips and other useful information. </p>
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如果我们删除了细菌中我们认为不重要的功能,又让他们做我们想让他们做的事情,那么这些细菌是否还保持正常生物体的状态呢?它们是否已经成为了一种生产机器了呢?为了解决这个问题,我们提出了一种艺术性的方法。众所周知,要想让我们的观念能够被大众更好地理解,生物艺术无疑是一种很好的方法。
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我们创建了一种机制能够解决这个问题。我们通过修饰大肠杆菌让它产生一种气味并且模仿柠檬成熟的过程,这个模型需要细菌和它赖以生存的培养基。我们通过五官的感知使这个模型看起来像一个柠檬,但是"ceci n’est pas un citron”——但事实上它并不是一个柠檬,我们只是让它看起来比较像而已。我们希望通过这个实例能够引发大家对生物实验的道德底线的思考。
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<tr><td colspan="3" > <h3> Tips  </h3></td></tr>
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<p>We are currently working on providing teams with some easy to use design templates.
 
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<br> In the meantime you can also view other team wikis for inspiration! Here are some very good examples</p>
 
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''This abstract was translated to Chinese by [https://2014.igem.org/Team:XMU-China iGEM XMU China] under our [https://2014.igem.org/Team:Paris_Saclay/Outreach/Collaborations collaborations].''
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<li> <a href="https://2013.igem.org/Team:SDU-Denmark/"> 2013 SDU Denmark </a> </li>
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<li> <a href="https://2013.igem.org/Team:SYSU-China">2013 SYSU China</a> </li>
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<li> <a href="https://2013.igem.org/Team:Shenzhen_BGIC_ATCG"> 2013 Shenxhen BGIG ATCG </a></li>
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Synteettisellä biologialla on mahdollisuus muuttaa yhteiskunnan paradigmoja, kuten käsitystämme soluista.
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<li> <a href="https://2013.igem.org/Team:Colombia_Uniandes">2013 Colombia Unianades </a></li>
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<li> <a href="https://2013.igem.org/Team:Lethbridge">2013 Lethbridge</a></li>
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<p>For a full wiki list, you can visit <a href="https://igem.org/Team_Wikis?year=2013">iGEM 2013 web sites </a> and <a href="https://igem.org/Team_Wikis?year=2012">iGEM 2012 web sites</a>  lists. </p>
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Jos karsimme bakteereista niiden “tarpeettomat” toiminnot ja valjastamme ne vastaamaan tarpeisiimme, ovatko bakteerit edelleen mielestämme eläviä eliöitä vai onko niistä tullut koneita? Kysymme tämän kysymyksen biotaiteen keinoin, sillä se on yksi parhaita tapoja herättää julkista keskustelua.
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Me luommekonseptiorganismin, joka heijastaa tätä keskustelua. Me muuntelemme ''Escherichia coli'' bakteeria niin, että se tuoksuu ja jäljittelee sitruunan kypsymistä. Teemme bakteerien ja kasvulaustan sekoituksen, joka tuoksuu, kypsyy ja näyttää aivan sitruunalta, mutta "ceci n’est pas un citron” se ei ole sitruuna… vai onko? Tämän avulla haluamme herättää kaikissa ajatuksia elävien organismien suunnitteluun liittyvistä tulevaisuuden mahdollisuuksista ja eettisistä rajoitteista.
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
 
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''This abstract was translated to Finnish by [https://2014.igem.org/Team:Aalto-Helsinki iGEM Aalto-­Helsinki] under our [https://2014.igem.org/Team:Paris_Saclay/Outreach/Collaborations collaborations].''
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and what you plan to do.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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La biologie synthétique a le pouvoir de changer certains paradigmes de notre société tel que notre conception du statut des êtres vivants.
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Si nous privons des bactéries de leurs fonctions "inutiles" pour qu'elles produisent ce dont nous avons besoin, peut-on toujours les considérer comme des organismes vivants ou sont-elles devenues des machines ?
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="">iGEM 2013 calendar</a> </li>
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<li>Have lots of fun! </li>
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Pour aborder cette question, nous avons adopté une approche artistique car nous pensons que le Bio-Art est l'un des meilleurs moyens de susciter des débats avec les citoyens. Nous avons créé un organisme-concept qui pourrait refléter ces interrogations : nous avons modifié ''Escherichia coli'' pour qu'elle produise une odeur de citron et aussi simuler son processus de maturation. Un mélange de bactéries et de milieu de croissance sera coulé dans un moule qui  sentira, mûrira et ressemblera à un citron. Mais "ceci n'est pas un citron"- ou cela l'est-il ? Avec notre réalisation nous lançons une invitation à la réflexion sur les futures opportunités et limites éthiques de la conception d’êtres vivants.
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La biologia sintetica potenzialmente ha il potere di cambiare i paradigmi della società come la nostra concezione di ciò che gli esseri viventi sono. Se priviamo i batteri di tutte le loro funzioni "inutili" e facciamo produrre loro ciò di cui abbiamo bisogno e desiderio, questi batteri possiedono ancora lo status di organismi viventi o sono diventati macchine? Per aumentare e esplorare questa domanda, abbiamo adottato un approccio artistico. Infatti, pensiamo che il '''Bio-Art''' è uno dei modi migliori per raggiungere i cittadini e stimolare il dibattito e la riflessione.
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Abbiamo deciso di creare un organismo ideale che riflettesse tali interrogatori. Abbiamo in programma di modificare ''Escherichia coli'' per produrre il '''profumo''' di un limone e simulare il processo di maturazione di un limone cambiando il suo colore gradualmente dal verde al giallo. Una miscela di batteri e  crescita solida si modellerà in una '''forma''' di limone: Odorerà come un limone, maturerà come un limone e sembrerà come un limone, ma "ceci n'est pas un citron" - questo non sarà un limone ... o lo è?
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Con questo progetto, invitiamo tutti a pensare alle prossime opportunità e ai limiti etici necessari di progettazione di esseri viventi.
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Quando iGEM Paris Saclay ti da limoni, rompete i vostri tabù!
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사물의 인식 및 개념은 우리가 사는 사회와 문화코드에 상당한 영향을 받습니다. 예를 들어, 옛날에는 어떤 인간은 다른 이의 소유물이었으며 그들의 생사는 주인이 결정하였습니다. 오늘날 이것이 도저히 용납이 안된다면 그것은 ‘인간’의 정의가 그동안 많이 바뀌었기 때문입니다.
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합성생물학은 사회의 패러다임을 바꿀 힘을 갖고 있습니다. ‘생물이란 무엇인가?’에 대한 새로운 답도 제시할 수 있습니다. 만약 박테리아에서 ‘필요없는’ 기능들을 제거하고 우리가 원하는 물질을 만들도록 하면, 이 박테리아는 아직도 살아있을까요? 아니면, 하나의 기계로 전락했을까요? 이 질문에 답하기 위해 저희는 예술의 힘을 빌리고자 합니다. 저희는 바이오아트 (BioArt)가 대중에게 다가가고 토론을 싹틔우기에 가장 좋은 방법이라 생각합니다.
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이런 생각들을 반영할만한 생명체를 만들고자 합니다. 대장균을 개조하여 레몬의 향과 색을 표현하는 것입니다. 특히, 과일이 익듯이 저희 대장균도 초록색에서 노란색으로 바뀔 것입니다. 레몬 모양의 틀을 이용하여 박테리아가 들어있는 배지도 레몬처럼 보이게 할 계획입니다. 결국 레몬향이 나고 레몬색도 띄고 레몬처럼 보이지만, “ceci n’est pas un citon” – 이것은 레몬이 아닙니다. 그런데 모든점이 레몬과 같다면, 정말 레몬이 아닐까요?
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저희 작품을 통해, 합성생물학의 윤리적인 한계에 대해서 다같이 생각해봅시다.
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iGEM Paris Saclay와 함께 당신의 터부를 버리세요!
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Synthetische biologie heft het vermogen om de visie van de maatschappij te veranderen zoals on beeld van wat levende wezens zijn.
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Als wij bacterieën ontdoen van hun ‘onnodige’ functies en ze laten produceren wat wij nodig hebben, hebben deze bacteriën dan nog de status van levende organismen, of zijn het machines geworden? Wij hebben een artistieke methode gekozen deze vraag op te werpen omdat Bio-Art de beste manier is om burgers met elkaar in debat te laten gaan.
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We hebben een concept organisme gemaakt dat deze vragen weerspiegelt. We modificeren Escheria coli om de geur van een rijpende citroen te produceren en het rijpingsproces te simuleren. We gieten een mix van bacteriën en groeimedium in een vorm: Zo zal het ruiken, rijpen en er uit zien als een citroen, maar “ceci n’est pas un citron” – dit is geen citroen… Of toch wel? Hiermee nodigen we iedereen uit om na te denken over toekomstige kansen en de ethische grenzen van het ontwerpen van levende wezens.
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''This abstract was translated to Dutch by [https://2014.igem.org/Team:Groningen iGEM Groningen] under our [https://2014.igem.org/Team:Paris_Saclay/Outreach/Collaborations collaborations].''
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Biologia syntetyczna ma moc zmieniania paradygmatów społecznych takich jak nasza koncepcja tego, czym są organizmy żywe. Jeśli pozbawimy bakterie ich „niepotrzebnych” funkcji i zmusimy je do produkcji tego, co nam potrzebne, czy nadal będą one posiadały status organizmów żywych czy staną się maszynami?
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Aby odpowiedzieć na to pytanie, przyjęliśmy podejście artystyczne, jako że Bio-Art jest jednym z najlepszych sposobów wskrzeszenia debaty wśród społeczeństwa. Stworzyliśmy koncepcję organizmu, która odzwierciedlałaby te dochodzenia. Zmodyfikowaliśmy Escherichia coli by wytwarzała zapach i imitowała proces dojrzewania cytryny. Mieszanina bakterii i pożywki odżywczej zostanie ukształtowana: będzie pachnieć, dojrzewać i wyglądać jak cytryna, ale "ceci n’est pas un citron” – to nie cytryna… a może jednak? Wraz z tym pytaniem zapraszamy wszystkich do rozważenia przyszłych okazji i granic etycznych projektowania żywych istot.
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''This abstract was translated to Polish by [https://2014.igem.org/Team:Warsaw iGEM Warsaw] under our [https://2014.igem.org/Team:Paris_Saclay/Outreach/Collaborations collaborations].''
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Syntetisk biologi er en mulighet til et paradigmeskifte i samfunnet med tanke på vår oppfatning av hva levende ting er. Hvis vi tar bort bakteriers ”unødvendige” funksjoner og får dem til å produsere ting som vi trenger, vil disse bakteriene fremdeles betraktes som levende organismer, eller har de blitt maskiner? For å sette fokus på denne problemstillingen har vi valgt en kunstnerisk tilnærming ettersom Bio-Kunst er en av de beste måtene å sette i gang en samfunnsdebatt på. Vi har skapt en konsept organisme som reflekterer denne problemstillingen. Vi har modifisert E. coli-bakterier til å produsere lukt og etterlikne modningsprosessen til en sitron. En blanding av bakterier og vekstmedium blandes sammen:  Det vil lukte som, modne som og se ut som, en sitron, men ”Ceci n’est pas un citron” – dette er ikke en sitron… eller er det?
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Med dette inviterer vi alle til å tenke over hvilke muligheter og etiske grenser vi har når vi designer levende skapninger.
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''This abstract was translated to Norwegian by [https://2014.igem.org/Team:UiOslo%20Norway iGEM UiOslo_Norway] under our [https://2014.igem.org/Team:Paris_Saclay/Outreach/Collaborations collaborations].''
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La biología sintética tiene el poder de cambiar los paradigmas de la sociedad como nuestra concepción de la definición del ser viviente.
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Si privamos las bacterias de todas sus funciones “inútiles” para que produzcan lo que necesitamos, ¿es que todavía poseen el estatuto de ser vivo o se convirtieron en máquinas?
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Para plantear esta cuestión, adoptamos un enfoque artístico porque creemos que el Bio-Arte es una de las mejores maneras para sensibilizar la población y provocar el debate. Hemos creado un organismo-concepto  que podría plantear estas interrogaciones: hemos modificado ''Escherichia coli'' para que produzca  el olor del limón y simula su proceso de maturación . Una mezcla de bacterias y de medio de crecimiento sólido será moldeada en un molde de limón: el “limón” olerá como a limón, madurará como un limón y se parecerá a un limón pero “ceci n’est pas un citron” – no es un limón… ¿o lo es?.
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Con este proyecto, invitamos a cada uno a pensar acerca de las oportunidades futuras y la necesidad de los límites éticos con respecto al diseño de seres vivos.
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Sentetik biyoloji, yaşayan canlılarla ve bizim açımızla toplum paradigmalarını değiştirme gücüne sahiptir.
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Eğer bizler bakterileri “gereksiz” fonksiyonlarından kurtarır ve kendi ihtiyaç duyduğumuz fonksiyonlar eklersek, bu bakteriler hala yaşayan canlı özelliklerine mi sahip olurlar yoksa birer makinaya mı dönüşürler?
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Bu soruyu irdelemek için, Bio-Art adında bir yaklaşım geliştirdik. Dizaynımızın bu sorunu toplumla tartışmak için iyi bir yol olduğunu düşünüyoruz. Bu sorgulamaları yansıtacak bir örnek organizma yarattık. Parfüm üretmek ve bir limonun olgunlaşma sürecini  uyarmak için Escherchia coli’yi modifiye ettik. Bir grup bakteri kültürü limon gibi olgunlaşacak, kokacak ve görünecek; ancak “ceci n’est pas un citron”-bu bir limon değil.. ya da öyle mi?
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Bu projeyle, herkesi yaklaşan fırsatlar ve canlıların etik tasarımının sınırları hakkında düşünmeye davet ediyoruz.
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''This abstract was translated to Turkish by [https://2014.igem.org/Team:METU%20Turkey iGEM METU_Turkey] under our [https://2014.igem.org/Team:Paris_Saclay/Outreach/Collaborations collaborations].''
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===We let you discover our [https://2014.igem.org/Team:Paris_Saclay/Project/Fastlemon FastLemon]===
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===We are social!===
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Follow our tweets by [http://www.twitter.com/iGEMParisSaclay @iGEMParisSaclay], check our photos on [http://instagram.com/igemparis @iGEMParis] and be updated with our news on [http://www.facebook.com/IgemParisSaclay2012 iGEMParisSaclay]'s wall.
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Latest revision as of 03:00, 18 October 2014

Project Abstract: This is not a lemon!

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Synthetic Biology has the power of potentially changing paradigms of society such as our conception of what living beings are. If we deprive bacteria from all their “unnecessary" functions and have them produce what we need and desire, do these bacteria still possess the status of living organisms or have they become machines? To raise and explore this question, we adopted an artistic approach. Indeed, we think that Bio-Art is one of the best ways to reach the citizens and to spark debate and reflection.

We decided to create a concept organism that would reflect these interrogations. We plan to modify Escherichia coli in order to produce the fragrance of a lemon and simulate the ripening process of a lemon by changing its color gradually from green to yellow. A mixture of bacteria and solid growth medium will be moulded in a lemon shape: it will smell like a lemon, ripe like a lemon and look like a lemon, but "ceci n’est pas un citron” - this is not a lemon… or is it?

With this project we invite everyone to think about the upcoming opportunities and the necessary ethical limits of designing living beings.

When life gives you lemons, break your taboos with Paris Saclay!

We let you discover our FastLemon

We are social!

Follow our tweets by [http://www.twitter.com/iGEMParisSaclay @iGEMParisSaclay], check our photos on [http://instagram.com/igemparis @iGEMParis] and be updated with our news on [http://www.facebook.com/IgemParisSaclay2012 iGEMParisSaclay]'s wall.